Interleukin 4 induces cultured monocytes/macrophages to form giant multinucleated cells.

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1

1985 • 749 citations

B-Cell Stimulatory Factor-1/Interleukin 4

1987 • 602 citations

The granulomatous inflammatory response. A review.

1976 • 549 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

TRANSFORMATION OF MONOCYTES IN TISSUE CULTURE INTO MACROPHAGES, EPITHELIOID CELLS, AND MULTINUCLEATED GIANT CELLS

1966 • 449 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

THE RELATIVE IMPORTANCE OF BLOOD MONOCYTES AND FIXED MACROPHAGES TO THE EXPRESSION OF CELL-MEDIATED IMMUNITY TO INFECTION

1970 • 326 citations

B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens.

1987 • 299 citations

The formation and properties of macrophage polykaryons (inflammatory giant cells)

1974 • 285 citations

Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.

1985 • 257 citations

CHARACTERIZATION OF A LYMPHOCYTE FACTOR WHICH ALTERS MACROPHAGE FUNCTIONS

1973 • 226 citations

Effects of B cell stimulatory factor-1/interleukin 4 on hematopoietic progenitor cells

1987 • 213 citations

A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3.

1985 • 174 citations

Macrophage Activation for Tumor Cytotoxicity: Increased Lymphokine Responsiveness of Peritoneal Macrophages During Acute Inflammation

1978 • 137 citations

Recombinant human gamma-interferon induces human monocyte polykaryon formation.

1984 • 134 citations

Lymphocyte-mediated modification of blood-derived macrophage function in vitro; inhibition of growth of intracellular mycobacteria with lymphokines.

1971 • 121 citations

Macrophage Aggregation in Vitro: A Correlate of Delayed Hypersensitivity

1970 • 103 citations

Ueber die phagocytäre Rolle der Tuberkelriesenzellen

1888 • 95 citations

Characterization of Migration Inhibitory Factor (MIF) from Guinea Pig Lymphocytes Stimulated with Concanavalin A

1972 • 83 citations

The origin of mononuclear cells in chronic inflammation and tuberculin reactions in the rat

1968 • 78 citations

Formation of multinucleate giant cells in organized epitheloid cell granulomas.

1974 • 75 citations

The fine structure of sarcoid and tuberculous granulomas

1970 • 74 citations

Fusion of Normal Rabbit Alveolar Macrophages Induced by Supernatant Fluids from BCG-Sensitized Lymph Node Cells After Elicitation by Antigen

1974 • 71 citations

Functional and biochemical studies of multinucleated giant cells derived from the culture of human monocytes.

1984 • 63 citations

Kinetics of multinucleate giant cell formation and their modification by various agents in foreign body reactions.

1973 • 61 citations

MIF-like activity of natural and recombinant human interferon-gamma and their neutralization by monoclonal antibody.

1985 • 59 citations

Two Migration Inhibitory Factors with Different Chromatographic Behavior and Isoelectric Points

1977 • 54 citations

Degradation of granuloma‐inducing micro‐organisms by macrophages

1970 • 51 citations

Hepatosplenic schistosomiasis: a great neglected disease of the liver.

1978 • 49 citations

Antigen-Mediated Fusion of Specifically Sensitized Rabbit Alveolar Macrophages

1972 • 46 citations

Biological Sciences: The Short Lived Small Lymphocyte as a Mediator of Cellular Immunity

1970 • 44 citations

Studies on the phagocytic capacity of macrophage polykaryons

1977 • 39 citations

Kinetics and ultrastructural studies of the induction of rat alveolar macrophage fusion by mediators released from mitogen-stimulated lymphocytes.

1981 • 39 citations

The role of phagocytosis and natural lymphokines in the fusion of alveolar macrophages to form Langhans giant cells.

1975 • 33 citations

The tumoricidal properties of inflammatory tissue macrophages and multinucleate giant cells.

1979 • 32 citations

A macrophage agglutinating factor produced during a pulmonary delayed hypersensitivity reaction.

1975 • 23 citations

Mouse pleural macrophages: characterization and comparison with mouse alveolar and peritoneal macrophages.

1982 • 20 citations

Macrophage-Agglutinating Factor Produced In Vitro by BCG-Sensitized Lymphocytes

1977 • 10 citations