Blockade of potentiated startle responding in rats by 5-hydroxytryptamine1A receptor ligands

Statistical principles in experimental design.

1962 • 27,228 citations

Statistical Principles in Experimental Design

1964 • 8,376 citations

Reconciling the role of central serotonin neurons in human and animal behavior

1986 • 989 citations

Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT

1983 • 759 citations

Serotonin function in anxiety

1987 • 467 citations

Mechanism of Action of Benzodiazepines

1976 • 437 citations

Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors

1985 • 367 citations

Neurochemical modulation of sensory-motor reactivity: Acoustic and tactile startle reflexes

1980 • 328 citations

Pharmacological and anatomical analysis of fear conditioning using the fear-potentiated startle paradigm.

1986 • 309 citations

Central serotonin receptors as targets for drug research

1987 • 306 citations

Evidence that mCPP may have behavioural effects mediated by central 5‐HT_1C receptors

1988 • 299 citations

Pharmacology and neurochemistry of buspirone.

1982 • 284 citations

Diazepam and flurazepam: Effects on conditioned fear as measured with the potentiated startle paradigm

1979 • 267 citations

Noradrenergic agonists and antagonists: Effects on conditioned fear as measured by the potentiated startle paradigm

1979 • 263 citations

Pharmacological and anatomical analysis of fear conditioning using the fear-potentiated startle paradigm.

1986 • 261 citations

Tryptophan-5-hydroxylase: function and control.

1974 • 237 citations

5-Hydroxytryptamine and punishment

1977 • 229 citations

Anticonflict effect of the putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT)

1984 • 221 citations

Behavioral effects of serotonin depletion and of p-chlorophenylalanine (a serotonin depletor) in rats

1970 • 196 citations

Serotonergic mechanisms in the behavioral effects of buspirone and gepirone

1986 • 194 citations

Buspirone: Effects on central monoaminergic transmission - possible relevance to animal experimental and clinical findings

1982 • 139 citations

The primate locus coeruleus and effects of clonidine on opiate withdrawal.

1982 • 137 citations

Are there selective ligands for 5-HT1A and 5-HT1B receptor binding sites in brain?

1986 • 136 citations

The effects of benzodiazepines and serotonergic manipulations on punished responding

1979 • 136 citations

Pustative anxiolytics 8-OH-DPAT, buspirone and TVX Q 7821 are agonists at 5-HT1A autoreceptors in the raphé nuclei

1986 • 128 citations

Behavioral and neurochemical studies on the anticonflict actions of buspirone

1984 • 119 citations

Mediation of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) by the putative 5-HT1A receptor

1987 • 109 citations

Serotonin does not mediate anxiolytic effects of buspirone in the fear-potentiated startle paradigm: comparison with 8-OH-DPAT and ipsapirone

1988 • 95 citations

Anxiolytic effects of buspirone and gepirone in the fear-potentiated startle paradigm

1988 • 93 citations

Behavioral studies with anxiolytic drugs. III. Antipunishment actions of buspirone in the pigeon do not involve benzodiazepine receptor mechanisms.

1986 • 81 citations

Neuropharmacology of Buspirone

1984 • 80 citations

Tryptamine antagonists and punished behavior.

1974 • 77 citations

Lack of central 5-hydroxytryptamine influence on the anticonflict activity of diazepam

1982 • 73 citations

Discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OHDPAT): implications for understanding the actions of novel anxiolytics

1987 • 71 citations

Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding.

1988 • 66 citations

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

1985 • 59 citations

Behavioral effects of several new anxiolytics and putative anxiolytics

1987 • 57 citations

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

1985 • 54 citations

Discriminative stimulus properties of buspirone in the pigeon.

1987 • 53 citations

Fear-enhanced acoustic startle is not attenuated by acute or chronic imipramine treatment in rats

1985 • 52 citations

Behavioral studies with anxiolytic drugs. IV. Serotonergic involvement in the effects of buspirone on punished behavior of pigeons.

1987 • 47 citations

The effects of d-lysergic acid diethylamide (LSD), 2,5-dimethoxy-4-methylamphetamine (DOM), pentobarbital and methaqualone on punished responding in control and 5,7-dihydroxytryptamine-treated rats

1981 • 28 citations

The effects of dimethoxyphenylethylamine and mescaline on classical conditioning in rats as measured by the potentiated startle response

1967 • 28 citations

LSD-induced alterations of investigatory responding in rats

1979 • 19 citations

Buspirone decreases the activity of serotonin-containing neurons in the dorsal raphe in freely-moving cats

1986 • 17 citations

Nonbenzodiazepine anxiolytics: insights into possible mechanisms of action.

1986 • 9 citations