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Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid

Data up to Jan 2025

Published1996
Citations241
References21

Total Citations Per Year

Abstract

References (21)

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1994 • 8,631 citations

Terfenadine-Ketoconazole Interaction

1993 • 654 citations

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1991 • 489 citations

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole

1994 • 407 citations

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1989 • 381 citations

A potentially hazardous interaction between erythromycin and midazolam

1993 • 352 citations

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1991 • 343 citations

Efficacy and long-term adverse effect pattern of lovastatin

1988 • 338 citations

Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole

1994 • 275 citations

Biotransformation of lovastatin

1991 • 195 citations

Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics

1993 • 191 citations

Dose of midazolam should be reduced during diltiazem and verapamil treatments.

1994 • 185 citations

In vitro and in vivo biotransformation of simvastatin, an inhibitor of HMG CoA reductase.

1990 • 152 citations

HMG-CoA reductase inhibitor-induced myopathy in the rat: cyclosporine A interaction and mechanism studies.

1991 • 144 citations

Plasma concentrations of triazolam are increased by concomitant ingestion of grapefruit juice

1995 • 140 citations

Plasma Concentration Profiles of Simvastatin 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Inhibitory Activity in Kidney Transplant Recipients with and without Ciclosporin

1993 • 138 citations

Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia

1993 • 120 citations

Determination of cisapride in plasma and animal tissues by high-performance liquid chromatography

1988 • 120 citations

In vitro forecasting of drugs which may interfere with the biotransformation of midazolam

1991 • 107 citations

Determination of itraconazole in plasma and animal tissues by high-performance liquid chromatography

1987 • 97 citations

Determination of mevinolin and mevinolinic acid in plasma and bile by reversed-phase high-performance liquid chromatography

1986 • 63 citations

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Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid (1996) – Clinical Pharmacology & Therapeutics | Metascience Observatory Explorer