Antithrombotic therapy after myocardial reperfusion in acute myocardial infarction

Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group.

1988 • 2,740 citations

Thrombolysis in Myocardial Infarction (TIMI) Trial, Phase I: A comparison between intravenous tissue plasminogen activator and intravenous streptokinase. Clinical findings through hospital discharge.

1987 • 2,245 citations

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

1985 • 2,003 citations

Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary atherosclerotic plaques underlying fatal occlusive thrombi.

1983 • 1,023 citations

A new murine monoclonal antibody reports an activation-dependent change in the conformation and/or microenvironment of the platelet glycoprotein IIb/IIIa complex.

1985 • 593 citations

A HAEMATOLOGIST

1989 • 567 citations

Thrombolytic Therapy: Current Status

1988 • 556 citations

Rheological aspects of thrombosis and haemostasis: basic principles and applications. ICTH-Report--Subcommittee on Rheology of the International Committee on Thrombosis and Haemostasis.

1986 • 486 citations

Insights into the pathogenesis of acute ischemic syndromes.

1988 • 483 citations

Marked platelet activation in vivo after intravenous streptokinase in patients with acute myocardial infarction.

1988 • 441 citations

Rapid and sustained coronary artery recanalization with combined bolus injection of recombinant tissue-type plasminogen activator and monoclonal antiplatelet GPIIb/IIIa antibody in a canine preparation.

1988 • 394 citations

Rheological Aspects of Thrombosis and Haemostasis: Basic Principles and Applications

1986 • 366 citations

A Randomized Trial of Intravenous Tissue Plasminogen Activator for Acute Myocardial Infarction with Subsequent Randomization to Elective Coronary Angioplasty

1987 • 362 citations

Rethrombosis after reperfusion with streptokinase: importance of geometry of residual lesions.

1984 • 322 citations

Influence of arterial damage and wall shear rate on platelet deposition. Ex vivo study in a swine model.

1986 • 293 citations

Intravenous recombinant tissue-type plasminogen activator in patients with acute myocardial infarction: a report from the NHLBI thrombolysis in myocardial infarction trial.

1986 • 291 citations

Incomplete lysis of thrombus in the moderate underlying atherosclerotic lesion during intracoronary infusion of streptokinase for acute myocardial infarction: quantitative angiographic observations.

1986 • 251 citations

Paradoxic elevation of fibrinopeptide A after streptokinase: Evidence for continued thrombosis despite intense fibrinolysis

1987 • 213 citations

Thrombolytic Therapy: Current Status

1988 • 209 citations

Thrombin activity of fibrin thrombi and soluble plasmic derivatives.

1983 • 170 citations

Mediation of reocclusion by thromboxane A2 and serotonin after thrombolysis with tissue-type plasminogen activator in a canine preparation of coronary thrombosis.

1988 • 153 citations

Multicenter reperfusion trial of intravenous anisoylated plasminogen streptokinase activator complex (APSAC) in acute myocardial infarction: Controlled comparison with intracoronary streptokinase

1988 • 145 citations

Formation and regulation of platelet and fibrin hemostatic plug

1987 • 135 citations

The pathological basis and microanatomy of occlusive thrombus formation in human coronary arteries

1981 • 120 citations

Acute coronary thrombolysis with recombinant human tissue-type plasminogen activator: Initial patency and influence of maintained infusion on reocclusion rate

1987 • 115 citations

Prevention of coronary artery reocclusion and reduction in late coronary artery stenosis after thrombolytic therapy in patients with acute myocardial infarction. A randomized study of maintenance infusion of recombinant human tissue-type plasminogen activator.

1988 • 101 citations

Importance of adequate heparin dosage in arterial angioplasty in a porcine model.

1988 • 100 citations

Factors influencing reocclusion after coronary thrombolysis for acute myocardial infarction

1986 • 96 citations

Role of heparin after intravenous thrombolytic therapy for acute myocardial infarction

1987 • 85 citations

Role of platelet activation and fibrin formation in thrombogenesis

1986 • 73 citations

Anisoylated plasminogen streptokinase activator complex in acute myocardial infarction: A placebo-controlled arteriographic coronary recanalization study

1987 • 68 citations

Appraisal of various thrombolytic agents in the treatment of acute myocardial infarction

1987 • 67 citations

Follow-up after coronary arterial reperfusion with intravenous streptokinase in relation to residual myocardial infarct artery narrowings

1985 • 58 citations

Usefulness of recanalization to luminal diameter of 0.6 millimeter or more with intracoronary streptokinase during acute myocardial infarction in predicting “normal” perfusion status, continued arterial patency and survival at one year

1987 • 47 citations

Streptokinase-induced, antibody-mediated platelet aggregation: A potential cause of clot propagation in vivo

1988 • 37 citations

Synergism of thrombolytic agents: investigational procedures and clinical potential.

1988 • 31 citations

Low dose aspirin after early thrombolysis in anterior wall acute myocardial infarction

1988 • 25 citations

Recurrent early ischemic events after thrombolysis for acute myocardial infarction

1987 • 20 citations

Short-term infarct vessel patency with aspirin and dipyridarnole started 24 to 36 hours after intravenous streptokinase

1988 • 10 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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