Uptake of sparfloxacin and norfloxacin by clinical isolates of Staphylococcus aureus

Cross-resistance to fluoroquinolones in multiple-antibiotic-resistant (Mar) Escherichia coli selected by tetracycline or chloramphenicol: decreased drug accumulation associated with membrane changes in addition to OmpF reduction

1989 • 378 citations

Mechanisms of action of and resistance to ciprofloxacin.

1987 • 262 citations

Differences in susceptibility to quinolones of outer membrane mutants of Salmonella typhimurium and Escherichia coli

1986 • 260 citations

Genetic and biochemical characterization of norfloxacin resistance in Escherichia coli

1986 • 222 citations

Isolation and characterization of norfloxacin-resistant mutants of Escherichia coli K-12

1986 • 202 citations

Endogenous active efflux of norfloxacin in susceptible Escherichia coli

1988 • 183 citations

Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation

1989 • 129 citations

Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain of Escherichia coli

1986 • 121 citations

Mutational resistance to 4-quinolone antibacterial agents

1984 • 101 citations

In vitro activity of AT-4140 against clinical bacterial isolates

1989 • 97 citations

Norfloxacin resistance in a clinical isolate of Escherichia coli

1987 • 72 citations

Characterization of mechanisms of quinolone resistance in Pseudomonas aeruginosa strains isolated in vitro and in vivo during experimental endocarditis

1989 • 64 citations

Factors influencing the accumulation of ciprofloxacin in Pseudomonas aeruginosa

1989 • 61 citations

Accumulation of enoxacin by Escherichia coli and Bacillus subtilis

1987 • 60 citations

In vitro activity of AT-4140 against quinolone- and methicillin-resistant Staphylococcus aureus

1990 • 37 citations