OH•-generation by adriamycin semiquinone and H2O2; An explanation for the cardiotoxicity of anthracycline antibiotics

How super is superoxide?

1981 • 1,294 citations

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1977 • 545 citations

Spin-trapping and direct electron spin resonance investigations of the redox metabolism of quinone anticancer drugs

1980 • 317 citations

The one-electron transfer redox potentials of free radicals. I. The oxygen/superoxide system

1976 • 287 citations

Interaction of daunomycin and its derivatives with DNA

1972 • 265 citations

Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

1977 • 258 citations

Adriamycin stimulated superoxide formation in submitochondrial particles

1977 • 256 citations

The redox potential of the system oxygen—superoxide

1974 • 219 citations

[109] Methods for the elevation of hepatic microsomal mixed function oxidase levels and cytochrome P-450

1967 • 168 citations

Inhibition of coenzyme Q10-enzymes, succinoxidase and NADH-oxidase, by adriamycin and other quinones having antitumor activity

1974 • 153 citations

Pulse radiolysis studies of antitumor quinones: Radical lifetimes, reactivity with oxygen, and one-electron reduction potentials

1981 • 124 citations

One-electron-transfer reactions in biochemical systems II. The reaction of free radicals formed in the enzymic oxidation

1969 • 113 citations

Inhibition of sodium-potassium-activated adenosine 5'-triphosphatase and ion transport by adriamycin.

1979 • 111 citations

Inhibition of oxidative phosphorylation in tumor cells and mitochondria by daunomycin and adriamycin

1976 • 74 citations

Identification of free hydroxyl radicals in respiring rat heart mitochondria by spin trapping with the nitrone DMPO

1981 • 68 citations

Electrochemical study of DNA-anthracyclines interaction

1978 • 65 citations

Spectrophotometric and fluorescence polarization studies of the binding of ethidium, daunomycin and mepacrine to DNA and to poly(I · C)

1977 • 61 citations

Microbodies (Peroxisomes) Containing Catalase in Myocardium: Morphological and Biochemical Evidence

1974 • 58 citations

Mitochondrial Formation of OH˙ Radicals by an Ubisemiquinone-Dependent Reaction An Alternative Pathway to the Iron-Catalysed Haber-Weiss Cycle

1982 • 46 citations