GroEL-GroES Cycling

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

SPIDER and WEB: Processing and Visualization of Images in 3D Electron Microscopy and Related Fields

1996 • 2,073 citations

The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex

1997 • 1,250 citations

A New Generation of the IMAGIC Image Processing System

1996 • 1,236 citations

Residues in chaperonin GroEL required for polypeptide binding and release

1994 • 645 citations

STRUCTURE AND FUNCTION IN GroEL-MEDIATED PROTEIN FOLDING

1998 • 576 citations

Dynamics of the Chaperonin ATPase Cycle: Implications for Facilitated Protein Folding

1994 • 461 citations

Mechanism of GroEL action: Productive release of polypeptide from a sequestered position under groes

1995 • 423 citations

Distinct actions of cis and trans ATP within the double ring of the chaperonin GroEL

1997 • 406 citations

Characterization of the Active Intermediate of a GroEL–GroES-Mediated Protein Folding Reaction

1996 • 403 citations

The Chaperonin ATPase Cycle: Mechanism of Allosteric Switching and Movements of Substrate-Binding Domains in GroEL

1996 • 385 citations

GroEL-mediated protein folding proceeds by multiple rounds of binding and release of nonnative forms

1994 • 359 citations

Location of a folding protein and shape changes in GroEL–GroES complexes imaged by cryo-electron microscopy

1994 • 334 citations

Kinetics for the Life Sciences

1995 • 333 citations

A quantitative assessment of the role of the chaperonin proteins in protein folding in vivo

1996 • 235 citations

A structural model for GroEL–polypeptide recognition

1997 • 191 citations

The Origins and Consequences of Asymmetry in the Chaperonin Reaction Cycle

1995 • 176 citations

Binding of a chaperonin to the folding intermediates of lactate dehydrogenase

1991 • 169 citations

The Hydrophobic Nature of GroEL-Substrate Binding

1995 • 135 citations

Binding, encapsulation and ejection: substrate dynamics during a chaperonin-assisted folding reaction

1997 • 92 citations

Affinity of chaperonin-60 for a protein substrate and its modulation by nucleotides and chaperonin-10

1994 • 92 citations

The formation of symmetrical GroEL‐GroES complexes in the presence of ATP

1994 • 90 citations

Native-like structure of a protein-folding intermediate bound to the chaperonin GroEL

1997 • 86 citations

Nature and Consequences of GroEL-Protein Interactions

1995 • 80 citations

Dynamics of the GroEL – Protein Complex: Effects of Nucleotides and Folding Mutants

1996 • 68 citations

Asymmetry, commitment and inhibition in the GroE ATPase cycle impose alternating functions on the two GroEL rings

1998 • 58 citations

Effect of GroEL on the Re-folding Kinetics of α-Lactalbumin

1996 • 51 citations

GroEL Locked in a Closed Conformation by an Interdomain Cross-link Can Bind ATP and Polypeptide but Cannot Process Further Reaction Steps

1996 • 51 citations

Interactions between the GroE Chaperonins and Rhodanese

1995 • 50 citations

GroES Promotes the T to R Transition of the GroEL Ring Distal to GroES in the GroEL−GroES Complex^†

1997 • 44 citations

Kinetic significance of GroEL14·(GroES7)2 complexes in molecular chaperone activity

1996 • 38 citations

How GroES Regulates Binding of Nonnative Protein to GroEL

1997 • 35 citations

Fluorescence Detection of Symmetric GroEL14(GroES7)2 Heterooligomers Involved in Protein Release during the Chaperonin Cycle

1996 • 33 citations

Chaperonin releases the substrate protein in a form with tendency to aggregate and ability to rebind to chaperonin

1995 • 33 citations

Theory of chaperonin action: Inertial model for enhancement of prokaryotic rubisco assembly

1992 • 8 citations

Deleted Work

1955 • 0 citations