Novel Tau Polymorphisms, Tau Haplotypes, and Splicing in Familial and Sporadic Frontotemporal Dementia

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

2012 • 10,051 citations

Frontotemporal lobar degeneration

1998 • 4,937 citations

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1998 • 1,344 citations

Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups.

1994 • 1,291 citations

Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17

1998 • 954 citations

Association of an Extended Haplotype in the Tau Gene with Progressive Supranuclear Palsy

1999 • 775 citations

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

1998 • 464 citations

Genetic evidence for the involvement of τ in progressive supranuclear palsy

1997 • 387 citations

5′ Splice Site Mutations in tau Associated with the Inherited Dementia FTDP-17 Affect a Stem-Loop Structure That Regulates Alternative Splicing of Exon 10

1999 • 294 citations

A study of the Lund‐Manchester research criteria for frontotemporal dementia

1997 • 218 citations

Inheritance of Frontotemporal Dementia

1999 • 208 citations

Corticobasal degeneration shares a common genetic background with progressive supranuclear palsy

2000 • 198 citations

Frequency of Tau Gene Mutations in Familial and Sporadic Cases of Non-Alzheimer Dementia

2001 • 170 citations

Sporadic Pick's disease: A tauopathy characterized by a spectrum of pathological τ isoforms in gray and white matter

2002 • 147 citations

Frequency oftau mutations in three series of non-Alzheimer's degenerative dementia

1999 • 137 citations

From genotype to phenotype: A clinical, pathological, and biochemical investigation of frontotemporal dementia and parkinsonism (FTDP-17) caused by the P301L tau mutation

1999 • 134 citations

Aberrant Splicing of tau Pre-mRNA Caused by Intronic Mutations Associated with the Inherited Dementia Frontotemporal Dementia with Parkinsonism Linked to Chromosome 17

2000 • 131 citations

The apolipoprotein E ε4 allele is not a significant risk factor for frontotemporal dementia

1998 • 97 citations

Tau gene polymorphisms and apolipoprotein E ε4 may interact to increase risk for Alzheimer’s disease

1999 • 62 citations

Possible association of the tau H1/H1 genotype with primary progressive aphasia

2003 • 43 citations

Corticobasal degeneration shares a common genetic background with progressive supranuclear palsy

2000 • 41 citations

The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease

2001 • 34 citations