Phase I and II Agents in Cancer Therapy: Two Cisplatin Analogues and High-Dose Cisplatin in Hypertonic Saline or With Thiosulfate Protection

Cisplatin

1984 • 942 citations

Cisplatin : current status and new developments

1980 • 746 citations

Intraperitoneal Cisplatin with Systemic Thiosulfate Protection

1982 • 494 citations

High-Dose Cisplatin in Hypertonic Saline

1984 • 335 citations

Toxic effects of cis-dichlorodiammineplatinum(II) in man.

1979 • 327 citations

Pharmacokinetics and dosage reduction of cis-diammine(1,1-cyclobutanedicarboxylato)platinum in patients with impaired renal function.

1984 • 304 citations

Platinum Coordination Complexes in Cancer Chemotherapy

1984 • 264 citations

Pharmacokinetics of cis-diammine-1,1-cyclobutane dicarboxylate platinum(II) in patients with normal and impaired renal function.

1984 • 242 citations

Dose-response and dose-survival advantage for high versus low-dose cisplatin combined with vinblastine and bleomycin in disseminated testicular cancer a southwest oncology group study

1984 • 188 citations

Effect of sodium thiosulfate on cis-dichlorodiammineplatinum(II) toxicity and antitumor activity in L1210 leukemia.

1980 • 171 citations

Alterations in the toxicity of cis-Dichlorodiammineplatinum-II and in tissue localization of platinum as a function of NaCl concentration in the vehicle of administration

1981 • 170 citations

The Role of cis-Platinum in Solid-Tumor Therapy

1979 • 166 citations

Carboplatin: a very active new cisplatin analog in the treatment of small cell lung cancer.

1985 • 151 citations

High-dose cisplatin with sodium thiosulfate protection.

1985 • 148 citations

A phase I and pharmacokinetic study of diamminecyclobutane-dicarboxylatoplatinum (NSC 241240).

1983 • 144 citations

Ovarian trials at the Royal Marsden

1985 • 110 citations

Preclinical studies on toxicity, antitumour activity and pharmacokinetics of cisplatin and three recently developed derivatives

1984 • 99 citations

Current NCI Preclinical Antitumor Screening in Vivo: Results of Tumor Panel Screening, 1976–1982, and Future Directions

1984 • 89 citations

Comparative activity and distribution studies of five platinum analogues in nude mice bearing human ovarian carcinoma xenografts.

1985 • 88 citations

High-dose platinum for the treatment of refractory ovarian cancer

1981 • 84 citations

High-dose cisplatin therapy using mannitol versus furosemide diuresis: comparative pharmacokinetics and toxicity.

1981 • 81 citations

Anticancer activity of cis-dichlorodiammineplatinum(II) and some relevant chemistry.

1979 • 75 citations

Phase I clinical and pharmacologic trial of carboplatin daily for 5 days.

1984 • 70 citations

Improvement in the therapeutic index of cisplatin (NSC 119875) by pharmacologically induced chloruresis in the rat.

1983 • 65 citations

Ophthalmologic toxicity after cis-dichlorodiammineplatinum(II) therapy.

1978 • 65 citations

USE OF HIGH DOSE CIS‐DICHLORODIAMMINE PLATINUM (II) (NSC—119875)^† FOLLOWING FAILURE ON PREVIOUS CHEMOTHERAPY FOR ADVANCED CARCINOMA OF THE OVARY

1981 • 64 citations

Antitumor activity and toxicity of cisplatin analogs.

1982 • 59 citations

Effects of second-generation platinum analogs on isolated PM-2 DNA and their cytotoxicity in vitro and in vivo.

1980 • 57 citations

Phase I study of carboplatin (CBDCA) in children with cancer.

1986 • 48 citations

Cis-diammine-1, 1-cyclobutane dicarboxylate platinum II (carboplatin) in the treatment of testicular germ-cell tumours: a preliminary report

1985 • 42 citations

Synthesis and antitumor activity of new platinum complexes

1982 • 42 citations

Carboplatin, an active drug in advanced head and neck cancer.

1986 • 38 citations

Carboplatin (JM8) as a single agent and in combination in the treatment of small cell lung cancer

1985 • 33 citations

Phase I study and pharmacokinetics of intraperitoneal carboplatin

1985 • 31 citations

Cis-dichlorodiammine platinum and adriamycin therapy for advanced gynecological and genitourinary neoplasms

1980 • 31 citations

Peripheral neuropathy after cis-platinum (II) (DDP) therapy.

1980 • 29 citations

Etoposide and very high dose cisplatin: salvage therapy for patients with advanced germ cell neoplasms.

1985 • 24 citations

Experimental Antitumor Activity of Platinum Coordination Complexes

1984 • 23 citations

Biliary Excretion, Renal Handling and Red Cell Uptake of Cisplatin and CBDCA in Animals

1984 • 21 citations

Synthesis and Testing of Platinum Analogues — An Overview

1984 • 18 citations

Studies on the pharmacokinetics and metabolism of cis-dichloro-trans-dihydroxy-bis-isopropylamine platinum(IV) in the dog.

1982 • 15 citations