Soluble receptors for tumour necrosis factor in clinical laboratory diagnosis

Shock and Tissue Injury Induced by Recombinant Human Cachectin

1986 • 2,587 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Two TNF receptors

1992 • 1,048 citations

Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists.

1993 • 837 citations

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

1994 • 799 citations

Induction of TH1 and TH2 responses: a key role for the ‘natural’ immune response?

1992 • 794 citations

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1988 • 739 citations

Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones.

1992 • 697 citations

Neopterin as a marker for activated cell-mediated immunity: Application in HIV infection

1988 • 573 citations

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

1992 • 473 citations

Increased levels of soluble tumor necrosis factor receptors in the sera and synovial fluid of patients with rheumatic diseases

1992 • 341 citations

Serum Levels of Tumor Necrosis Factor- (TNF ) and Soluble TNF Receptors in Human Immunodeficiency Virus Type 1 Infection-Correlations to Clinical, Immunologic, and Virologic Parameters

1994 • 302 citations

TUMOUR NECROSIS FACTOR AS AN AUTOCRINE TUMOUR GROWTH FACTOR FOR CHRONIC B-CELL MALIGNANCIES

1988 • 282 citations

Increased serum levels of soluble receptors for tumor necrosis factor in cancer patients.

1991 • 234 citations

Imbalance between tumour necrosis factor-alpha and soluble TNF receptor concentrations in severe meningococcaemia. The J5 Study Group.

1992 • 203 citations

Influence of nephrectomy on tumor necrosis factor clearance in a murine model.

1993 • 182 citations

Correlation between serum levels of soluble tumor necrosis factor receptor and disease activity in systemic lupus erythematosus

1993 • 177 citations

Differential Expression of Proinflammatory Cytokines and Their Inhibitors during the Course of Meningococcal Infections

1994 • 175 citations

Evaluation of measurement of human TNF in plasma by ELISA.

1991 • 158 citations

Slow release of soluble TNF receptors by monocytes in vitro.

1994 • 150 citations

Cytokines in Acute Myocardial Infarction

1994 • 149 citations

Interferon gamma induces the expression of human immunodeficiency virus in persistently infected promonocytic cells (U1) and redirects the production of virions to intracytoplasmic vacuoles in phorbol myristate acetate-differentiated U1 cells.

1992 • 148 citations

Soluble tumor necrosis factor receptors in human inflammatory synovial fluids

1993 • 129 citations

Release of Soluble Receptors for Tumor Necrosis Factor in Clinical Sepsis and Experimental Endotoxemia

1993 • 122 citations

Tumor necrosis factor, its receptors and the connection with interleukin 1 and interleukin 6

1993 • 119 citations

Tumour Necrosis Factor-α and Lipopolysaccharide Enhance Interferon-Induced Tryptophan Degradation and Pteridine Synthesis in Human Cells

1989 • 113 citations

Soluble Receptors for Tumor Necrosis Factor as Predictors of Progression to AIDS in Asymptomatic Human Immunodeficiency Virus Type 1 Infection

1994 • 113 citations

Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1

1989 • 110 citations

Tumor necrosis factor and HIV P24 antigen levels in serum of HIV-infected populations.

1988 • 109 citations

Soluble Tumor Necrosis Factor Receptors Correlate with Parasitemia and Disease Severity in Human Malaria

1992 • 106 citations

Patterns of Proinflammatory Cytokines and Inhibitors during Typhoid Fever

1994 • 101 citations

Tumour necrosis factor (TNF) binding proteins (soluble TNF receptor forms) with possible roles in inflammation and malignancy.

1993 • 98 citations

Production of Cytokines by Peripheral Blood Monocytes/Macrophages Infected with Human Immunodeficiency Virus Type I (HIV-I)

1990 • 98 citations

High levels of circulating soluble receptors for tumor necrosis factor in hairy cell leukemia and type B chronic lymphocytic leukemia.

1992 • 97 citations

Decreased plasma concentrations of HDL cholesterol in HIV-infected individuals are associated with immune activation.

1994 • 97 citations

Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation

1989 • 94 citations

Cytokine abnormalities in human lupus

1992 • 93 citations

Increased serum levels of soluble receptors for tumor necrosis factor in cancer patients.

1991 • 86 citations

Elevated serum levels of soluble tumour necrosis factor receptors (sTNF-R) in patients with HIV infection

1992 • 84 citations

Cytokine Assays: Role in Evaluation of the Pathogenesis of Autoimmunity

1991 • 83 citations

Serum soluble markers of immune activation and disease activity in systemic lupus erythematosus

1995 • 78 citations

Circulating interleukin-1 and tumor necrosis factor antagonists in liver disease

1993 • 74 citations

Increased levels of intercellular adhesion molecule‐1 (ICAM‐1) and tumor necrosis factor receptor in the cerebrospinal fluid of patients with multiple sclerosis

1993 • 73 citations

Macrophage tumor necrosis factor-alpha release is induced by contact with some tumors.

1990 • 70 citations

Adherence of neutrophils induces release of soluble tumor necrosis factor receptor forms.

1994 • 64 citations

Increased serum concentrations of soluble tumor necrosis factor receptors in HIV-infected individuals are associated with immune activation.

1994 • 62 citations

Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation.

1993 • 61 citations

Interleukin-6, gamma interferon, and tumor necrosis factor receptors in typhoid fever related to outcome of antimicrobial therapy

1993 • 60 citations

Elevated TNF receptor plasma concentrations in patients with rheumatoid arthritis

1992 • 60 citations

High concentrations of soluble tumor necrosis factor receptors in ascites

1992 • 59 citations

Evaluation of soluble tumor necrosis factor (TNF) receptors and TNF receptor antibodies in patients with systemic lupus erythematodes, progressive systemic sclerosis, and mixed connective tissue disease

1993 • 55 citations

Interleukin-1 beta induces interleukin-1 receptor antagonist and tumor necrosis factor binding protein in humans.

1993 • 54 citations

Cytokines in Acute Myocardial Infarction

1994 • 54 citations

Tumor necrosis factor alpha and soluble tumor necrosis factor receptors in individuals with human immunodeficiency virus infection

1994 • 53 citations

Cytokine dysregulation in AIDS: in vivo overexpression of mRNA of tumor necrosis factor-alpha and its correlation with that of the inflammatory cytokine GRO.

1992 • 50 citations

Serum cytokine levels in patients undergoing bone marrow transplantation.

1993 • 49 citations

Increased immune activation during and after physical Eexercise

1993 • 47 citations

Neopterin and soluble tumor necrosis factor receptor type I in alcohol-induced cirrhosis

1995 • 39 citations

Circulating tumor necrosis factor alpha (TNF), soluble TNF receptors, and interleukin-6 in human subacute bacterial endocarditis

1993 • 37 citations

INTRAVENOUS FEEDING

1974 • 34 citations

Measurement of the Soluble Membrane Receptors for Tumor Necrosis Factor and Lymphotoxin in the Sera of Patients with Gynecologic Malignancy

1993 • 29 citations

Serum soluble tumour necrosis factor receptor 55 is increased in patients with haematological neoplasias and is associated with immune activation and weight loss

1993 • 28 citations

Increased Concentrations of Soluble Tumor Necrosis Factor Receptor 75 but Not of Soluble Intercellular Adhesion Molecule-1 Are Associated with the Decline of CD4+ Lymphocytes in HIV Infection

1994 • 23 citations

Serum levels of the soluble receptor for tumor necrosis factor in patients with renal disease

1994 • 22 citations

Low levels of specific T cell activation marker CD27 accompanied by elevated levels of markers for non-specific immune activation in the cerebrospinal fluid of patients with AIDS dementia complex

1993 • 19 citations

Soluble Tumor Necrosis Factor Receptor Expression in Patients with Metastatic Renal Cell Carcinoma Treated with Interleukin-2-Based lmmunotherapy

1993 • 12 citations

Relationship between soluble tumor necrosis factor (TNF) receptors and TNF? during immunotherapy with interleukin-2 and/or interferon ?

1994 • 11 citations

Correlation of Body Mass Index with Urinary Neopterin in Individuals Infected with Human Immunodeficiency Virus

1994 • 10 citations

Evaluation of soluble tumor necrosis factor receptors after orthotopic liver transplantation.

1992 • 8 citations

Soluble tumor necrosis factor receptors in patients with recurrent hepatitis C virus infection after liver transplantation

1994 • 4 citations