The mitochondrial DNA molecule ofDrosophila yakuba: Nucleotide sequence, gene organization, and genetic code

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

tRNA punctuation model of RNA processing in human mitochondria

1981 • 2,386 citations

Sequence and gene organization of mouse mitochondrial DNA

1981 • 1,712 citations

Mitochondrial DNA sequences of primates: Tempo and mode of evolution

1982 • 1,578 citations

Complete sequence of bovine mitochondrial DNA conserved features of the mammalian mitochondrial genome

1982 • 1,491 citations

Replication of animal mitochondrial DNA

1982 • 1,221 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

STRUCTURE OF RIBOSOMAL RNA

1984 • 793 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Characterization of translational initiation sites inE. coli

1982 • 673 citations

Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids

1983 • 643 citations

A different genetic code in human mitochondria

1979 • 558 citations

Compilation of tRNA sequences

1985 • 530 citations

Distinctive features of the 5′-terminal sequences of the human mitochondrial mRNAs

1981 • 355 citations

On the evolutionary descent of organisms and organelles: a global phylogeny based on a highly conserved structural core in small subunit ribosomal RNA

1984 • 352 citations

Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids.

1983 • 351 citations

The tRNA genes punctuate the reading of genetic information in human mitochondrial DNA

1980 • 311 citations

The pattern of transcription of the human mitochondrial rRNA genes reveals two overlapping transcription units

1983 • 307 citations

Identification of initiation sites for heavy-strand and light-strand transcription in human mitochondrial DNA.

1982 • 303 citations

Drosophila melanogaster mitochondrial DNA, a novel organization and genetic code

1983 • 300 citations

Precise identification of individual promoters for transcription of each strand of human mitochondrial DNA

1984 • 297 citations

Codon recognition rules in yeast mitochondria.

1980 • 293 citations

Messenger RNA in heat-shocked Drosophila cells

1977 • 292 citations

Different pattern of codon recognition by mammalian mitochondrial tRNAs.

1980 • 272 citations

Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs

1980 • 248 citations

Methylation of single-stranded DNA in vitro introduces new restriction endonuclease cleavage sites

1978 • 246 citations

A systematic DNA sequencing strategy

1982 • 213 citations

Replication of Mitochondrial DNA. Circular Replicative Intermediates in Mouse L Cells

1972 • 205 citations

Secondary structure of the large subunit ribosomal RNA from Escherichia coli, Zea mays chloroplast, and human and mouse mitochondrial ribosomes

1981 • 197 citations

Xenopus laevis28S ribosomal RNA: a secondary structure model and its evolutionary and functional implications

1984 • 196 citations

Secondary structure comparisons between small subunit ribosomal RNA molecules from six different species

1981 • 186 citations

Five TGA “stop” codons occur within the translated sequence of the yeast mitochondrial gene for cytochrome c oxidase subunit II

1979 • 184 citations

SEQ: a nucleotide sequence analysis and recombination system

1982 • 179 citations

Location and structure of the var1 gene on yeast mitochondrial DNA: Nucleotide sequence of the 40.0 allele

1982 • 169 citations

The structure of rat 28S ribosomal ribonucleic add inferred from the sequence of nuclotides in a gene

1983 • 168 citations

Sequence analysis of 28S ribosomal DNA from the amphibianXenopus laevis

1983 • 164 citations

The Organization of Highly Repeated DNA Sequences in Drosophila melanogaster Chromosomes

1974 • 164 citations

Biogenesis of mitochondria: the mitochondrial gene (aap1) coding for mitochondrial ATPase subunit 8 inSaccharomyces cerevisiae

1983 • 158 citations

Precise localization and nucleotide sequence of the two mouse mitochondrial rRNA genes and three immediately adjacent novel tRNA genes

1980 • 146 citations

The ribosomal RNA genes ofDrosophilamitochondrial DNA

1985 • 138 citations

A mammalian mitochondrial serine transfer RNA lacking the “dihydrouridine” loop and stem

1980 • 135 citations

A model for the tertiary structure of mammalian mitochondrial transfer RNAs lacking the entire ‘dihydrouridine’ loop and stem.

1983 • 131 citations

SEQUENCE EVOLUTION OF DROSOPHILA MITOCHONDRIAL DNA

1985 • 128 citations

Oxford surveys on eukaryotic genes

1984 • 126 citations

Compilation of sequences of tRNA genes

1984 • 126 citations

Origin and direction of replication in mitochondrial DNA molecules from the genus Drosophila.

1980 • 118 citations

Drosophilamitochondrial DNA: a novel gene order

1982 • 117 citations

Replication of Circular DNA in Eukaryotic Cells

1974 • 115 citations

A computer program to search for tRNA genes.

1980 • 111 citations

Origin and direction of replication in mitochondrial DNA molecules from Drosophila melanogaster.

1978 • 107 citations

Structural heterogeneity of mitochondrial DNA molecules within the genus Drosophila.

1976 • 106 citations

Identification of a promoter for transcription of the heavy strand of human mtDNA: In vitro transcription and deletion mutagenesis

1984 • 90 citations

Expression of the mitochondrial genome in xenopus laevis: a map of transcripts

1979 • 89 citations

Characterization and mapping of mitochondrial ribosomal RNA and mitochondrial DNA in Drosophila melanogaster

1976 • 89 citations

Extensive diversity among Drosophila species with respect to nucleotide sequences within the adenine + thymine-rich region of mitochondrial DNA molecules

1980 • 85 citations

Genes for cytochromecoxidase subunit I, URF2, and three tRNAs inDrosophilamitochondrial DNA

1983 • 82 citations

Knowledge-based simulation of genetic regulation in bacteriophage lambda

1984 • 79 citations

The nucleotide sequence of a small (3S) seryl-tRNA (anticodon GCU) from beef heart mitochondria

1980 • 79 citations

Sequences of the coding and flanking regions of the large ribosomal subunit RNA gene of mosquito mitochondria

1984 • 71 citations

Analysis of a DNA segment from rat liver mitochondria containing the genes for the cytochrome oxidase subunits I, II and III, ATPase subunit 6, and several tRNA genes

1981 • 70 citations

Antibodies against synthetic peptides reveal that the unidentified reading frame A6L, overlapping the ATPase 6 gene, is expressed in human mitochondria

1983 • 70 citations

Sequence homologies amongE. coli ribosomal proteins: Evidence for evolutionarily related groupings and internal duplications

1980 • 69 citations

The sequences of the small ribosomal RNA gene and the phenylalanine tRNA gene are joined end to end in human mitochondrial DNA

1980 • 68 citations

DNA sequence of theXenopus laevismitochondrial heavy and light strand replication origins and flanking tRNA genes

1983 • 67 citations

Unorthodox codon reading and the evolution of the genetic code

1981 • 67 citations

Sequence and arrangement of the genes for cytochromeb, URF1, URF4L, URF4, URF5, URF6 and five tRNAs inDrosophilamitochondrial DNA

1984 • 64 citations

Compilation of tRNA sequences

1984 • 63 citations

ISOLATION AND CHARACTERIZATION OF MITOCHONDRIAL DNA FROM DROSOPHILA MELANOGASTER

1973 • 61 citations

Nucleotide sequence of a segment ofDrosophilamitochondrial DNA that contains the genes for cytochromecoxidase subunits II and III and ATPase subunit 6

1983 • 58 citations

Mitochondrial DNA from Drosophila melanogaster

1973 • 57 citations

Mapping of mitochondrial DNA in Xenopus laevis and X. borealis: The positions of ribosomal genes and D-loops

1978 • 54 citations

Identification of the polypeptides encoded in the ATPase 6 gene and in the unassigned reading frames 1 and 3 of human mtDNA.

1983 • 52 citations

All eight unassigned reading frames of mouse mitochondrial DNA are expressed.

1984 • 49 citations

Transfer RNA genes inDrosophilamitochondrial DNA: related 5' flanking sequences and comparisons to mammalian mitochondrial tRNA genes

1983 • 45 citations

Mitochondrial DNA in Drosophila

1981 • 42 citations

Non-random patterns of nucleotide substitutions and codon strategy in the mammalian mitochondrial genes coding for identified and unidentified reading frames.

1983 • 40 citations

Comparison of the Human and Bovine Mitochondrial Genomes

1982 • 39 citations

Tumor-associated mutations of rat mitochondrial transfer RNA genes

1983 • 36 citations

Crystal Structure of Yeast tRNA phe and General Structural Features of Other tRNAs

1979 • 32 citations

A cluster of six tRNA genes inDrosophilamitochondrial DNA that includes a gene for an unusual tRNA^ser_AGY

1984 • 30 citations

Sequence and structure of a serine transfer RNA with GCU anticodon from mosquito mitochondria

1984 • 27 citations

The Drosophila mitochondrial genome.

1984 • 25 citations

A major lysine tRNA with a CUU anticodon in insect mitochondria

1983 • 25 citations

Replication of Mitochondrial DNA: Replicative Forms of Molecules from Rat Tissues and Evidence for Discontinuous Replication

1974 • 24 citations

Mapping of mitochondrial 4S RNA genes in Xenopus laevis by electron microscopy

1978 • 23 citations

Sequences of three transfer RNAs from mosquito mitochondria

1983 • 22 citations

Transcription of Polytene Chromosomes and of the Mitochondrial Genome in Drosophila melanogaster

1978 • 19 citations

Sequence and structure of a methionine transfer RNA from mosquito mitochondria

1984 • 19 citations

Biological Handbooks I: Cell Biology

1977 • 15 citations

Pulse-label analysis and mapping of the two terminal regions of asynchronous complementary strand replication of mitochondrial DNA in transformed hamster cells

1980 • 14 citations

Transcription of cloned transfer RNA genes fromDrosophila melanogasterin a homologous cell-free extract

1982 • 13 citations

Expression of the Mouse Mitochondrial DNA Genome

1982 • 11 citations

Mammalian Mitochondrial tRNAs: A Modified Nucleotide 3′ to the Anticodon May Modulate Their Codon Response

1982 • 6 citations

3′ Termini of Mammalian and Insect Mitochondrial rRNAs

1982 • 4 citations

TRANSCRIPTION PATTERN OF DROSOPHILA MELANOGASTER MITOCHONDRIAL DNA11This investigation was supported by grant no. NP-9E from the American Cancer Society and grant no. CA-12312-08 from the National Cancer Institute. J.B. and J.L.R.R. are Medical Scientist Training Program Fellows of the National Institute of General Medical Sciences (GM-07365-03) and D.A.C. is a Faculty Research Awardee of the American Cancer Society (FRA-136).

1979 • 2 citations