Inhibition by angiotensin II type 1 receptor antagonist of cardiac phenotypic modulation after myocardial infarction

Effect of Enalapril on Survival in Patients with Reduced Left Ventricular Ejection Fractions and Congestive Heart Failure

1991 • 8,296 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications.

1990 • 2,864 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system.

1991 • 2,017 citations

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

1993 • 1,347 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

Ventricular Remodeling after Myocardial Infarction

1993 • 752 citations

Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril.

1985 • 726 citations

Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion.

1986 • 715 citations

Expression of the cardiac ventricular alpha- and beta-myosin heavy chain genes is developmentally and hormonally regulated.

1984 • 609 citations

Construction of DNA sequences complementary to rat .alpha.1 and .alpha.2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D

1984 • 568 citations

Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium.

1988 • 557 citations

Collagen Network of the Myocardium: Function, Structural Remodeling and Regulatory Mechanisms

1994 • 491 citations

Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure.

1991 • 466 citations

Experimental myocardial infarction in the rat: qualitative and quantitative changes during pathologic evolution.

1978 • 460 citations

Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion.

1986 • 438 citations

The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.

1991 • 429 citations

Cardiac alpha- and beta-myosin heavy chain genes are organized in tandem.

1984 • 320 citations

Experimental Myocardial Infarction

1961 • 313 citations

Molecular basis of cardiac performance. Plasticity of the myocardium generated through protein isoform switches.

1989 • 308 citations

cDNA cloning by PCR of rat transforming growth factor β-1

1990 • 274 citations

Pharmacological profile of a highly potent and long-acting angiotensin II receptor antagonist, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4- yl]methyl]-1H-benzimidazole-7-carboxylic acid (CV-11974), and its prodrug, (+/-)-1-(cyclohexyloxycarbonyloxy)-ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5- yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate (TCV-116).

1993 • 211 citations

Coordinate regulation of the levels of type III and type I collagen mRNA in most but not all mouse fibroblasts.

1985 • 194 citations

Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats.

1993 • 185 citations

Angiotensin II Receptor Blockade After Myocardial Infarction in Rats

1992 • 178 citations

Global cardiac remodeling after acute myocardial infarction: A study in the rat model

1985 • 174 citations

Regulation of myosin isoenzyme composition in fetal and neonatal rat ventricle by endogenous thyroid hormones.

1984 • 170 citations

Expression of the genes coding for the skeletal muscle and cardiac actins in the heart

1984 • 157 citations

DNA synthesis in the non-infarcted cardiac interstitium after left coronary artery ligation in the rat: Effects of captopril

1991 • 156 citations

Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload--induced cardiac hypertrophy demonstrated by in situ hybridization.

1989 • 154 citations

Contribution of Cardiac Renin-Angiotensin System to Ventricular Remodelling in Myocardial-Infarcted Rats

1993 • 153 citations

Left ventricular failure induced by myocardial infarction. I. Myocyte hypertrophy

1985 • 152 citations

Interstitial Collagen is Increased in the Non-infarcted Human Myocardium After Myocardial Infarction

1993 • 148 citations

Contractility and stiffness of noninfarcted myocardium after coronary ligation in rats. Effects of chronic angiotensin converting enzyme inhibition.

1991 • 132 citations

Role of angiotensin II in renal injury of deoxycorticosterone acetate-salt hypertensive rats.

1994 • 119 citations

Neurohumoral responses to chronic myocardial infarction in rats.

1988 • 116 citations

Skeletal muscle actin mRNA. Characterization of the 3′ untranslated region

1981 • 102 citations

Coronary Vascular Remodeling and Myocardial Fibrosis in the Rat with Renovascular Hypertension Response to Captopril

1991 • 101 citations

Changes in Gene Expression during Cardiac Growth

1991 • 95 citations

Fibrosis-induced reduction of endomyocardium in the rat after isoproterenol treatment.

1989 • 72 citations

Antihypertensive effects of a highly potent and long-acting angiotensin II subtype-1 receptor antagonist, (+-)-1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H- benzimidazole-7-carboxylate (TCV-116), in various hypertensive rats.

1994 • 70 citations

Analysis of thyroid hormone effects on myosin heavy chain gene expression in cardiac and soleus muscles using a novel dot-blot mRNA assay

1985 • 69 citations

Does converting enzyme inhibition change the neuronal and extraneuronal uptake of catecholamines?

1991 • 61 citations

Antithetical accumulation of myosin heavy chain but not alpha-actin mRNA isoforms during early stages of pressure-overload-induced rat cardiac hypertrophy.

1993 • 44 citations

Contribution of cardiac renin-angiotensin system to ventricular remodeling in myocardial-infarcted rats

1993 • 27 citations

Cardiac Hypertrophy-Related Gene Expression in Spontaneously Hypertensive Rats: Crucial Role of Angiotensin AT1 Receptor

1995 • 15 citations