The effects of free fatty acids on gluconeogenesis and glycogenolysis in normal subjects

Starvation in Man

1970 • 1,242 citations

Measurement of Size and Turnover Rate of Body Glucose Pool by the Isotope Dilution Method

1956 • 827 citations

Epinephrine plasma metabolic clearance rates and physiologic thresholds for metabolic and hemodynamic actions in man.

1980 • 588 citations

Contributions of gluconeogenesis to glucose production in the fasted state.

1996 • 470 citations

The Control of Glycogen Metabolism in the Liver

1976 • 438 citations

The control of glycogen metabolism in the liver

1970 • 414 citations

HORMONAL REGULATION OF HEPATIC GLUCONEOGENESIS AND GLYCOLYSIS

1988 • 402 citations

Effects of glucocorticoids on carbohydrate metabolism

1988 • 391 citations

Mechanism for the stimulation of gluconeogenesis by fatty acids in perfused rat liver.

1966 • 388 citations

Control Mechanisms of Gluconeogenesis and Ketogenesis

1969 • 303 citations

Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans

1992 • 297 citations

Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine.

1995 • 277 citations

Book ReviewObesity.

1970 • 244 citations

Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans.

1998 • 231 citations

Metabolic effects of nicotinic acid and its derivatives

1971 • 213 citations

Use of 2H2O for estimating rates of gluconeogenesis. Application to the fasted state.

1995 • 178 citations

Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans. Demonstration of hepatic autoregulation without a change in plasma glucose concentration.

1990 • 162 citations

Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans.

1993 • 160 citations

The relationship between gluconeogenic substrate supply and glucose production in humans

1990 • 134 citations

Inhibition of lipolysis by nicotinic acid and by acipimox

1980 • 130 citations

Effect of Hyperinsulinemia on Urea Pool Size and Substrate Oxidation Rates

1988 • 125 citations

Contribution of net hepatic glycogenolysis to glucose production during the early postprandial period

1996 • 124 citations

Determination of gluconeogenesis in vivo with 14C-labeled substrates

1985 • 119 citations

Glucose turnover and gluconeogenesis in human pregnancy.

1997 • 103 citations

In vivo evidence for hepatic autoregulation during FFA-stimulated gluconeogenesis in normal humans

1991 • 86 citations

Inhibition of Lipolysis Decreases Lipid Oxidation and Gluconeogenesis From Lactate But Not Fasting Hyperglycemia or Total Hepatic Glucose Production in NIDDM

1993 • 61 citations

Calculation of substrate flux using stable isotopes

1988 • 58 citations

Influence of hyperthyroidism on splanchnic exchange of glucose and gluconeogenic precursors.

1981 • 52 citations

Effects of Therapy on the Nature and Quantity of Fuels Oxidized During Diabetic Ketoacidosis

1980 • 50 citations

Splanchnic and renal exchange of infused fructose in insulin-deficient type 1 diabetic patients and healthy controls.

1989 • 50 citations

Control of hepatic gluconeogenesis: Role of fatty acid oxidation

1989 • 49 citations

Inhibition by infused glycerol of gluconeogenesis from other precursors

1971 • 49 citations

Evidence for Dual Control Mechanism Regulating Hepatic Glucose Output in Nondiabetic Men

1991 • 45 citations

Role of fat-derived substrates in the regulation of gluconeogenesis during fasting

1996 • 42 citations

Effects of an acute increase in plasma triglyceride levels on glucose metabolism in man

1995 • 37 citations

Regulation of hepatic gluconeogenesis in the guinea pig by fatty acids and ammonia

1975 • 35 citations

Effects of 4-Pentenoic Acid on Carbohydrate Metabolism in Pigeon Liver Homogenate

1969 • 34 citations

In Vivoandin VitroEffects of Antiinsulin Receptor Antibodies*

1984 • 31 citations

Influence of Arginine on Splanchnic Glucose Metabolism in Man

1979 • 29 citations

Nicotinic acid and its derivatives: a short survey.

1983 • 27 citations

Fatty acids are potent modulators of lactate utilization in isolated hepatocytes from fed rats

1993 • 27 citations

Mitochondrial redox state and the regulation of gluconeogenesis in the isolated, perfused cat liver

1973 • 19 citations

Release, oxidation, and reesterification of fatty acids from infused triglycerides: Effect of heparin

1995 • 17 citations

Stable Isotope Techniques for the Study of Gluconeogenesis in Man

1997 • 15 citations

Lithium movements in resting and chemotactic factor-activated human neutrophils

1988 • 11 citations