Administration of a cAMP Phosphodiesterase 4 Inhibitor Enhances Antidepressant-Induction of BDNF mRNA in Rat Hippocampus

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

1995 • 2,090 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus

1996 • 1,200 citations

Requirement for BDNF in Activity-Dependent Survival of Cortical Neurons

1994 • 974 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1993 • 851 citations

Antidepressant-Like Effect of Brain-derived Neurotrophic Factor (BDNF)

1997 • 829 citations

Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain

1995 • 470 citations

The Molecular Biology of Cyclic Nucleotide Phosphodiesterases

1999 • 432 citations

Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes

1992 • 412 citations

Recent Progress in Understanding the Hormonal Regulation of Phosphodiesterases

1995 • 313 citations

Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain

1997 • 296 citations

Chronic Antidepressant Administration Alters the Subcellular Distribution of Cyclic AMP‐Dependent Protein Kinase in Rat Frontal Cortex

1989 • 196 citations

Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamine

1994 • 170 citations

Antinociceptive effect of brain-derived neurotrophic factor and neurotrophin-3

1994 • 165 citations

Rolipram in Major Depressive Disorder: Results of a Double-Blind Comparative Study with Imipramine

1989 • 155 citations

A Multicenter Double-Blind Study of Three Different Doses of the New cAMP-Phosphodiesterase Inhibitor Rolipram in Patients with Major Depressive Disorder

1992 • 149 citations

Expression of Neurotrophins and Their Receptors in Primary Astroglial Cultures: Induction by Cyclic AMP‐Elevating Agents

1994 • 121 citations

Effect of chronic restraint stress and tianeptine on growth factors, growth-associated protein-43 and microtubule-associated protein 2 mRNA expression in the rat hippocampus

1998 • 114 citations

Chronic Electroconvulsive Treatment Augments Coupling of the GTP‐Binding Protein G_s to the Catalytic Moiety of Adenylyl Cyclase in a Manner Similar to That Seen with Chronic Antidepressant Drugs

1991 • 110 citations

Rolipram, a novel antidepressant drug, reverses the hypothermia and hypokinesia of monoamine-depleted mice by an action beyond postsynaptic monoamine receptors

1986 • 100 citations

Is Phosphodiesterase inhibition a new mechanism of antidepressant action?

1988 • 93 citations

Antidepressant-like effects of rolipram and other inhibitors of cyclic adenosine monophosphate phosphodiesterase on behavior maintained by differential reinforcement of low response rate.

1993 • 80 citations

In-patient major depression: is rolipram as effective as amitriptyline?

1991 • 76 citations

Chronic Antidepressant Treatment Down-Regulates the Induction of c-fos mRNA in Response to Acute Stress in Rat Frontal Cortex

1995 • 74 citations

Rolipram versus lmipramine in Inpatients with Major, ???Minor??? or Atypical Depressive Disorder: A Double-Blind Double-Dummy Study Aimed at Testing a Novel Therapeutic Approach

1988 • 64 citations

Behavioral effects of rolipram and structurally related compounds in mice: Behavioral sedation of cAMP phosphodiesterase inhibitors

1991 • 43 citations

Interaction of metoprolol with lorazepam and bromazepam

1991 • 42 citations

Antidepressant properties of some phosphodiesterase inhibitors.

1983 • 26 citations

Review : Stress, Antidepressant Treatments, and Neurotrophic Factors: Molecular and Cellular Mechanisms

1995 • 24 citations

A preliminary study of possible psychoactive effects of intravenous forskolin in depressed and schizophrenic patients

1996 • 20 citations

Localization of putative calcium-responsive regions in the rat BDNF gene

1997 • 17 citations

Recent progress in understanding the hormonal regulation of phosphodiesterases

1995 • 17 citations

Chronic Antidepressant Treatment Down-Regulates the Induction of c-fos mRNA in Response to Acute Stress in Rat Frontal Cortex

1995 • 16 citations

Deleted Work

1955 • 0 citations