Multiple roles for PrP in the prion diseases

Mice devoid of PrP are resistant to scrapie

1993 • 2,058 citations

Prion protein is necessary for normal synaptic function

1994 • 802 citations

Normal host prion protein necessary for scrapie-induced neurotoxicity

1996 • 791 citations

Altered circadian activity rhythms and sleep in mice devoid of prion protein

1996 • 655 citations

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

1994 • 563 citations

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

1996 • 506 citations

Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene

1996 • 483 citations

GABA regulation of circadian responses to light. I. Involvement of GABAA-benzodiazepine and GABAB receptors

1989 • 148 citations

GABAA, GABAC, and NMDA receptor subunit expression in the suprachiasmatic nucleus and other brain regions

1995 • 99 citations