Two species of phospholipase C isolated from lymphocytes produce specific ratios of inositol phosphate products

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones

1983 • 547 citations

Identification and properties of two distinct phosphatidylinositol-specific phospholipase C enzymes from sheep seminal vesicular glands.

1982 • 248 citations

Purification of phosphatidylinositol-specific phospholipase C from rat liver.

1981 • 180 citations

Phospholipid Turnover in Hormone Action

1984 • 178 citations

The enzymic formation of myoinositol 1:2-cyclic phosphate from phosphatidylinositol

1971 • 177 citations

Ion Exchange Chromatography of Intact Brain Phosphoinositides on Diethylaminoethyl Cellulose by Gradient Salt Elution in a Mixed Solvent System

1964 • 176 citations

Isolation and characterization of the inositol cyclic phosphate products of polyphosphoinositide cleavage by phospholipase C. Physiological effects in permeabilized platelets and Limulus photoreceptor cells.

1985 • 167 citations

Guanosine 5'-O-thiotriphosphate stimulates phospholipase C activity in plasma membranes of rat hepatocytes.

1985 • 154 citations

Studies on myo-Inositol Phosphates of Natural Origin

1959 • 143 citations

<scp>d</scp>-myoInositol 1:2-cyclic phosphate 2-phosphohydrolase

1972 • 128 citations

Inositol cyclic phosphates are produced by cleavage of phosphatidylphosphoinositols (polyphosphoinositides) with purified sheep seminal vesicle phospholipase C enzymes.

1985 • 103 citations

Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium

1985 • 83 citations

Multiple forms of phosphoinositide-specific phospholipase C of different relative molecular masses in animal tissues. Evidence for modification of the platelet enzyme by Ca2+-dependent proteinase

1984 • 74 citations

Rat brain and liver soluble phospholipase C: Resolution of two forms with different requirements for calcium

1985 • 63 citations

The formation of inositol 1,2-cyclic phosphate on agonist stimulation of phosphoinositide breakdown in mouse pancreatic minilobules. Evidence for direct phosphodiesteratic cleavage of phosphatidylinositol.

1985 • 60 citations

Resolution into two different forms and study of the properties of phosphatidylinositol-specific pospholipase C from human platelet cytosol

1982 • 57 citations

Partial purification of a phosphatidylinositol phosphodiesterase isolated from lymphocytes

1985 • 4 citations