ATP synthases?Structure of the F1-moiety and its relationship to function and mechanism

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

A Schematic Method of Deriving the Rate Laws for Enzyme-Catalyzed Reactions

1956 • 994 citations

Amino-acid sequence of the catalytic subunit of the (Na+ + K+)ATPase deduced from a complementary DNA

1985 • 762 citations

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

1986 • 538 citations

The UNC operon nucleotide sequence, regulation and structure of ATP-synthase

1984 • 519 citations

Primary structure and subunit stoichiometry of F1-ATPase from bovine mitochondria

1985 • 498 citations

Mechanism of ATP hydrolysis by beef heart mitochondrial ATPase. Rate constants for elementary steps in catalysis at a single site.

1982 • 409 citations

Catalytic site cooperativity of beef heart mitochondrial F1 adenosine triphosphatase. Correlations of initial velocity, bound intermediate, and oxygen exchange measurements with an alternating three-site model.

1982 • 347 citations

Structure and function of proton-translocating adenosine triphosphatase (F0F1): biochemical and molecular biological approaches

1983 • 310 citations

The presence of two hydrolytic sites on beef heart mitochondrial adenosine triphosphatase.

1981 • 305 citations

Substrate positions and induced-fit in crystalline adenylate kinase

1977 • 304 citations

The organization and sequence of the genes for ATP synthase subunits in the cyanobacterium Synechococcus 6301

1987 • 286 citations

Reconstitution of a functional coupling factor from the isolated subunits of Escherichia coli F1 ATPase.

1980 • 276 citations

Structures of the genes for the β and ε subunits of spinach chloroplast ATPase indicate a dicistronic mRNA and an overlapping translation stop/start signal

1982 • 270 citations

Three-dimensional structure of adenyl kinase

1974 • 258 citations

PROTON ATPASES: STRUCTURE AND MECHANISM

1983 • 255 citations

Adenosine Triphosphatase from Rat Liver Mitochondria

1971 • 225 citations

Identification of a tyrosine residue at a nucleotide binding site in the beta subunit of the mitochondrial ATPase with p-fluorosulfonyl[14C]-benzoyl-5'-adenosine.

1978 • 207 citations

Protein Folding

1981 • 206 citations

Reconstitution of adenosine triphosphatase of thermophilic bacterium from purified individual subunits.

1977 • 194 citations

Structural properties of protein β-sheets

1983 • 193 citations

Phosphofructokinase: structure and control

1981 • 183 citations

NMR studies of the magnesium-ATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme

1985 • 160 citations

DNA sequence around the Escherichia coli unc operon. Completion of the sequence of a 17 kilobase segment containing asnA, oriC, unc, glmS and phoS

1984 • 159 citations

Cooperatively between catalytic sites in the mechanism of action of beef heart mitochondrial adenosine triphosphatase.

1981 • 157 citations

Two conformations of crystalline adenylate kinase

1977 • 146 citations

Nucleotide sequence of the Rhodospirillum rubrum atp operon

1985 • 144 citations

ATP synthase from bovine mitochondria

1987 • 141 citations

Adenine nucleotide binding sites on beef heart F1 ATPase: photoaffinity labeling of beta-subunit Tyr-368 at a noncatalytic site and beta Tyr-345 at a catalytic site.

1987 • 137 citations

Rhodopseudomonas blastica atp operon

1984 • 134 citations

Secretion of Escherichia coli beta-lactamase from Bacillus subtilis by the aid of alpha-amylase signal sequence.

1982 • 131 citations

Structure of the complex of yeast adenylate kinase with the inhibitor P1,P5-di(adenosine-5′-)pentaphosphate at 2.6 Å resolution

1987 • 131 citations

The sites of labeling of the beta-subunit of bovine mitochondrial F1-ATPase with 8-azido-ATP.

1983 • 130 citations

Structure and function of H+-ATPase

1979 • 127 citations

The wheat chloroplast gene for CF₀ subunit I of ATP synthase contains a large intron

1985 • 125 citations

A gene cluster in the spinach and pea chloroplast genomes encoding one CF1 and three CF0 subunits of the H+-ATP synthase complex and the ribosomal protein S2

1987 • 124 citations

Biochemistry and Genetics of Bacterial H+-Translocating ATPases

1981 • 123 citations

Structure of mitochondrial F1-ATPase studied by electron microscopy and image processing

1986 • 123 citations

Nucleotide sequence of tobacco chloroplast gene for the α subunit of proton–translocating ATPase

1983 • 119 citations

Characterization of the cysteinyl-containing peptides of the gamma subunit of coupling factor 1.

1984 • 119 citations

A sixth subunit of ATP synthase, an F0 component, is encoded in the pea chloroplast genome

1986 • 117 citations

Nuclear genes coding the yeast mitochondrial adenosine triphosphatase complex. Primary sequence analysis of ATP2 encoding the F1-ATPase beta-subunit precursor.

1985 • 110 citations

Structure of the nucleotide‐binding domain in the β‐subunit of Escherichia coli F₁‐ATPase

1986 • 108 citations

Adenine nucleotide-binding sites on beef heart F1-ATPase. Conditions that affect occupancy of catalytic and noncatalytic sites.

1986 • 107 citations

The NH2-terminal portion of the alpha subunit of Escherichia coli F1 ATPase is required for binding the delta subunit.

1980 • 105 citations

Inactivation of the bovine heart mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyl[3H]inosine is accompanied by modification of tyrosine 345 in a single beta subunit.

1986 • 104 citations

Identification of the essential tyrosine residue in the beta subunit of bovine heart mitochondrial F1-ATPase that is modified by 7-chloro-4-nitro[14C]benzofurazan.

1984 • 98 citations

Adenosine triphosphatase from rat liver mitochondria. Crystallization and x-ray diffraction studies of the F1-component of the enzyme.

1978 • 96 citations

Adenine nucleotide binding sites on beef heart F1-ATPase. Asymmetry and subunit location.

1987 • 94 citations

Directed mutagenesis of the beta-subunit of F1-ATPase from Escherichia coli.

1987 • 90 citations

Characterization of the purified membrane attachment (δ) subunit of the proton translocating adenosine triphosphatase from Escherichia coli

1977 • 89 citations

Three copies of the beta subunit must be modified to achieve complete inactivation of the bovine mitochondrial F1-ATPase by 5'-p-fluorosulfonylbenzoyladenosine.

1986 • 86 citations

Identification of the lysine residue to which the 4-nitrobenzofurazan group migrates after the bovine mitochondrial F1-ATPase is inactivated with 7-chloro-4-nitro[14C]benzofurazan.

1984 • 84 citations

An Electron Microscopic Approach to the Quaternary Structure of Mitochondrial F₁‐ATPase

1983 • 82 citations

Mutations in the active site of Escherichia coli phosphofructokinase

1987 • 80 citations

The subunit composition of the mitochondrial oligomycin‐insensitive ATPase

1971 • 79 citations

.beta. Subunit of rat liver mitochondrial ATP synthase: cDNA cloning, amino acid sequence, expression in Escherichia coli and structural relationship to adenylate kinase

1988 • 77 citations

STRUCTURE AND FUNCTION OF H⁺‐ATPase: WHAT WE HAVE LEARNED FROM Escherichia coli H⁺‐ATPase*

1982 • 76 citations

Structure of the mitochondrial F1 ATPase at 9-A resolution.

1982 • 71 citations

The defective proton-ATPase of uncD mutants of Escherichia coli. Identification by DNA sequencing of residues in the beta-subunit which are essential for catalysis or normal assembly.

1987 • 71 citations

Human F1-ATPase: Molecular Cloning of cDNA for the Beta Subunit12

1986 • 70 citations

Trinitrophenyl-ATP and -ADP bind to a single nucleotide site on isolated beta-subunit of Escherichia coli F1-ATPase. In vitro assembly of F1-subunits requires occupancy of the nucleotide-binding site on beta-subunit by nucleoside triphosphate.

1988 • 69 citations

Synthesis of Enzyme-Bound ATP by Mitochondrial Soluble F1-ATPase in the Presence of Dimethylsulfoxide1

1983 • 68 citations

Binding of adenine nucleotides to the purified 13S coupling factor of bacterial oxidative phosphorylation

1976 • 64 citations

Evidence for functional heterogeneity among the catalytic sites of the bovine heart mitochondrial F1-ATPase.

1987 • 58 citations

Mitochondrial ATP synthase. Interaction of a synthetic 50-amino acid, beta-subunit peptide with ATP.

1988 • 57 citations

The defective proton-ATPase of uncA mutants of Escherichia coli. Identification by DNA sequencing of residues in the alpha-subunit which are essential for catalysis or normal assembly.

1987 • 57 citations

Tyrosine-311 of a beta chain is the essential residue specifically modified by 4-chloro-7-nitrobenzofurazan in bovine heart mitochondrial ATPase

1985 • 51 citations

Lack of ability of trypsin‐treated mitochondrial F₁‐ATPase to bind the oligomycin‐sensitivity conferring protein (OSCP)

1983 • 45 citations

Stable Structure of Thermophilic Proton ATPase Beta Subunit12

1986 • 41 citations

Characterization of Human Salivary Kallikrein: Reactivities to Human Plasma Kininogens and Proteinase Inhibitors

1983 • 41 citations

Proton adenosine triphosphatase complex of rat liver. The effect of trypsin on the F1 and F0 moieties of the enzyme.

1981 • 41 citations

Rate of chase-promoted hydrolysis of ATP in the high affinity catalytic site of beef heart mitochondrial ATPase.

1988 • 36 citations

Ligand binding studies of the F1 moiety of rat liver ATP synthase: implications about the enzyme's structure and mechanism

1987 • 33 citations

Electron microscopy of beef heart mitochondrial F₁‐ATPase

1984 • 31 citations

Functionally distinct beta subunits in F1-adenosinetriphosphatase.

1985 • 31 citations

The proton adenosine triphosphatase complex of rat liver mitochondria. Temperature-dependent dissociation-reassociation of the F1-ATPase subunits

1984 • 30 citations

Single-Site Catalysis of F1-ATPase from Thennophilic Bacterium PS3 and Its Dominance in Steady-State Catalysis at Low ATP Concentration1

1987 • 28 citations

The structure of the δ-subunit from chloroplast coupling factor (CF1) in solution

1977 • 27 citations

Electron microscopy of beef heart F1-ATPase crystals.

1983 • 25 citations

Evidence for catalytic cooperativity during ATP hydrolysis by beef heart F1-ATPase. Kinetics and binding studies with the photoaffinity label BzATP.

1987 • 21 citations

The epsilon subunit and inhibitory monoclonal antibodies interact with the carboxyl-terminal region of the beta subunit of Escherichia coli F1-ATPase.

1987 • 20 citations

Chemical evidence for probably nonequivalent .beta. subunits in F1 adenosine triphosphatase

1984 • 18 citations

P1-(5'-adenosyl)-P2-N-(2-mercaptoethyl)diphosphoramidate. An affinity reagent for demonstrating the presence of Tyr-beta 311 at the hydrolytic site of F1-ATPase.

1987 • 17 citations

Structure of F1-ATPases

1981 • 16 citations

Identification of an essential β chain lysine residue from bovine heart mitochondrial ATPase specifically modified with nitrobenzofurazan

1985 • 15 citations

The structure of the ε-subunit from the chloroplast coupling factor (CF1) studied by means of small angle X-ray scattering and inelastic light scattering

1977 • 14 citations

Structure of the yeast mitochondrial adenosine triphosphatase. Results of trypsin degradation.

1981 • 14 citations

Catalytic hydrolysis and synthesis of adenosine 5'-triphosphate by stereoisomers of covalently labeled F1-adenosine triphosphatase and reconstituted submitochondrial particles

1987 • 13 citations

Mitochondrial ATP synthase complex: interaction of its F1 adenosine triphosphatase moiety with the heavy atom iodine

1987 • 4 citations

Flip-flop model of energy interconversion by ATP synthetase.

1974 • 4 citations

Fluorometric evidence for control of the activity of F1-adenosinetriphosphatase by ligand-induced conformation change

1986 • 3 citations