Influence of 5-HT3 receptor antagonists and the indirect 5-HT agonist, dexfenfluramine, on heroin self-administration in rats

A psychomotor stimulant theory of addiction.

1987 • 2,704 citations

Cellular and Molecular Mechanisms of Drug Dependence

1988 • 2,094 citations

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

1984 • 644 citations

Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems

1982 • 560 citations

5‐Hydroxytryptamine Receptors

1993 • 524 citations

Conditioned place preference as a measure of drug reward.

1989 • 456 citations

Effects of the 5‐HT₃ receptor antagonist, GR38032F, on raised dopaminergic activity in the mesolimbic system of the rat and marmoset brain

1987 • 354 citations

Heroin reward is dependent on a dopaminergic substrate

1981 • 333 citations

Neurobiology of an anorectic drug: Fenfluramine

1986 • 319 citations

Attenuation of heroin reward in rats by disruption of the mesolimbic dopamine system

1983 • 309 citations

Brain reward systems and abuse

1988 • 274 citations

Drug reinstatement of heroin-reinforced responding in the rat

1983 • 266 citations

Fluoxetine reduces intravenous cocaine self-administration in rats

1990 • 254 citations

Serotonin manipulations and the structure of feeding behaviour

1986 • 249 citations

The ventral pallidum plays a role in mediating cocaine and heroin self-administration in the rat

1990 • 223 citations

The Neuropharmacological Basis of Reward

1992 • 193 citations

Reinstatement of Drug-Taking Behavior as a Method of Assessing Incentive Motivational Properties of Drugs

1987 • 182 citations

Fluoxetine pretreatment reduces breaking points on a progressive ratio schedule reinforced by intravenous cocaine self-administration in the rat

1991 • 182 citations

5HT3 receptor antagonists block morphine- and nicotine-but not amphetamine-induced reward

1989 • 176 citations

Blockade of nucleus accumbens opiate receptors attenuates intravenous heroin reward in the rat

1985 • 175 citations

Mechanisms of effects of d-Fenfluramine on brain serotonin metabolism in rats: Uptake inhibition versus release

1988 • 157 citations

Cocaine self-administration is increased by both D1 and D2 dopamine antagonists

1991 • 138 citations

NMDA receptors in the nucleus accumbens modulate intravenous cocaine but not heroin self-administration in the rat

1992 • 124 citations

Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat.

1984 • 117 citations

Effect of 5‐HT₃ receptor antagonists on responses to selective activation of mesolimbic dopaminergic pathways in the rat

1990 • 109 citations

The effects of putative 5-hydroxytryptamine receptor active agents ond-amphetamine self-administration in controls and rats with 5,7-dihydroxytryptamine median forebrain bundle lesion

1984 • 102 citations

Dopaminergic mediation of reward produced by direct injection of enkephalin into the ventral tegmental area of the rat

1983 • 95 citations

Effect of drugs influencing 5-HT function on ethanol drinking and feeding behaviour in rats: Studies using a drinkometer system

1992 • 92 citations

Effect of the 5-HT3 receptor antagonists, MDL72222 and ondansetron on morphine place conditioning

1992 • 86 citations

Suppression of food intake in rats by fluoxetine: Comparison of enantiomers and effects of serotonin antagonists

1988 • 78 citations

Reduction in oral ethanol self-administration in the rat by the 5-HT uptake blocker fluoxetine

1990 • 61 citations

Effects of 5, 7-dihydroxytryptamine lesions of the nucleus accumbens on rat inravenous morphine self-administration

1987 • 43 citations

A Rodent Model for Nicotine Self-Administration

2003 • 41 citations

Role of serotonin and catecholamines in brain in the feeding suppressant effect of fluoxetine

1992 • 37 citations

Drug-induced place preference in rats with 5,7-dihydroxytryptamine lesions of the nucleus accumbens

1988 • 31 citations

Conditioned Reinforcement as a Measure of the Rewarding Properties of Drugs

1987 • 26 citations

Effect of Morphine Dose Size on the Conditioned Reinforcing Potency of Stimuli Paired with Morphine

1972 • 25 citations

Different effects of zimelidine on the reinforcing properties of d-amphetamine and morphine on conditioned place preference in rats

1986 • 23 citations

Effect of dexfenfluramine on alcohol intake in alcohol-preferring “P” rats

1992 • 23 citations

Preliminary findings with the indirect 5-HT agonist dexfenfluramine on heroin discrimination and self-administration in rats

1993 • 20 citations