Molecular Sorting in the Secretory Pathway

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Current Topics in Membranes and Transport

1970 • 1,240 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

[6] Preparation of microsomal membranes for cotranslational protein translocation

1983 • 679 citations

Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family

1988 • 564 citations

Comparative studies of intracellular transport of secretory proteins.

1978 • 452 citations

The subunit structure of the high affinity insulin receptor. Evidence for a disulfide-linked receptor complex in fat cell and liver plasma membranes.

1980 • 388 citations

Two distinct intracellular pathways transport secretory and membrane glycoproteins to the surface of pituitary tumor cells

1982 • 340 citations

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles.

1986 • 331 citations

Expressing a human proinsulin cDNA in a mouse ACTH-secreting cell. Intracellular storage, proteolytic processing, and secretion on stimulation

1983 • 329 citations

Direct identification of prohormone conversion site in insulin-secreting cells

1985 • 297 citations

The trans-most cisternae of the Golgi complex: A compartment for sorting of secretory and plasma membrane proteins

1987 • 275 citations

Visualization of acidic organelles in intact cells by electron microscopy.

1984 • 250 citations

Insulin receptor: covalent labeling and identification of subunits.

1979 • 243 citations

Chloroquine diverts ACTH from a regulated to a constitutive secretory pathway in AtT-20 cells

1983 • 198 citations

The signal recognition particle receptor is a complex that contains two distinct polypeptide chains.

1986 • 189 citations

Determinants for protein localization: beta-lactamase signal sequence directs globin across microsomal membranes.

1984 • 149 citations

Secretory protein targeting in a pituitary cell line: differential transport of foreign secretory proteins to distinct secretory pathways.

1985 • 145 citations

The Golgi apparatus remains associated with microtubule organizing centers during myogenesis.

1985 • 141 citations

Re-routing of a secretory protein by fusion with human growth hormone sequences

1986 • 138 citations

Sorting of three secretory proteins to distinct secretory granules in acidophilic cells of cow anterior pituitary.

1987 • 117 citations

Hormonal Induction of Secretory Granules in a Pituitary Tumor Cell Line*

1986 • 107 citations

Secretory granules of an anterior pituitary cell line, AtT-20, contain only mature forms of corticotropin and beta-lipotropin.

1981 • 105 citations

Coordinate, equimolar secretion of smaller peptide products derived from pro-ACTH/endorphin by mouse pituitary tumor cells.

1981 • 98 citations

Selective packaging of human growth hormone into synaptic vesicles in a rat neuronal (PC12) cell line.

1985 • 94 citations

A subclass of proteins and sulfated macromolecules secreted by AtT-20 (mouse pituitary tumor) cells is sorted with adrenocorticotropin into dense secretory granules.

1983 • 69 citations

Targeting of secretory vesicles to cytoplasmic domains in AtT-20 and PC-12 cells

1988 • 64 citations

Efficient targeting to storage granules of human proinsulins with altered propeptide domain.

1988 • 64 citations

Subunit structure of the insulin receptor of the human lymphocyte

1980 • 61 citations

Sorting and secretion of adrenocorticotropin in a pituitary tumor cell line after perturbation of the level of a secretory granule-specific proteoglycan.

1984 • 52 citations

Somatostatin discriminates between the intracellular pathways of secretory and membrane proteins.

1984 • 50 citations

Influence of cytosolic pH on receptor-mediated endocytosis of asialoorosomucoid

1988 • 48 citations

(Pro)insulin associates with Golgi membranes of pancreatic B cells.

1984 • 43 citations

The insulin cell: Its cellular environment and how it processes (Pro)insulin

1986 • 36 citations

Chapter 6 Protein Sorting in the Secretory Pathway

1985 • 21 citations