Structure and Ubiquitin Binding of the Ubiquitin-interacting Motif

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1997 • 33,348 citations

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

THE UBIQUITIN SYSTEM

1998 • 8,360 citations

AP-1 as a regulator of cell life and death

2002 • 2,752 citations

Analytical ultracentrifugation in biochemistry and polymer science

1995 • 1,970 citations

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1997 • 1,724 citations

Structure of ubiquitin refined at 1.8 Å resolution

1987 • 1,682 citations

Recognition of the polyubiquitin proteolytic signal

2000 • 1,651 citations

Ubiquitin-Dependent Sorting into the Multivesicular Body Pathway Requires the Function of a Conserved Endosomal Protein Sorting Complex, ESCRT-I

2001 • 1,373 citations

Receptor downregulation and multivesicular-body sorting

2002 • 1,192 citations

Efficient anisotropic refinement of macromolecular structures using FFT

1999 • 943 citations

Analysis of data from the analytical ultracentrifuge by nonlinear least-squares techniques

1981 • 845 citations

A 26 S protease subunit that binds ubiquitin conjugates.

1994 • 759 citations

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

2002 • 692 citations

A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

2002 • 626 citations

Improved Sensitivity of HSQC Spectra of Exchanging Protons at Short Interscan Delays Using a New Fast HSQC (FHSQC) Detection Scheme That Avoids Water Saturation

1995 • 621 citations

Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

1998 • 576 citations

Gettin’ down with ubiquitin: turning off cell-surface receptors, transporters and channels

1999 • 461 citations

A ubiquitin-interacting motif conserved in components of the proteasomal and lysosomal protein degradation systems

2001 • 438 citations

Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

2002 • 417 citations

Proteins containing the UBA domain are able to bind to multi-ubiquitin chains

2001 • 405 citations

The UBA domain: a sequence motif present in multiple enzyme classes of the ubiquitination pathway

1996 • 397 citations

The Multiubiquitin-Chain-Binding Protein Mcb1 Is a Component of the 26S Proteasome in Saccharomyces cerevisiae and Plays a Nonessential, Substrate-Specific Role in Protein Turnover

1996 • 393 citations

Ubiquitin Enters the New Millennium

2001 • 390 citations

Myc—Max—Mad: a transcription factor network controlling cell cycle progression, differentiation and death

1994 • 365 citations

A Function for Monoubiquitination in the Internalization of a G Protein–Coupled Receptor

1998 • 364 citations

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

2001 • 362 citations

Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4

2002 • 362 citations

The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting

2002 • 345 citations

AP-2/Eps15 Interaction Is Required for Receptor-mediated Endocytosis

1998 • 345 citations

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

1996 • 336 citations

Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

2001 • 324 citations

UBA domains of DNA damage-inducible proteins interact with ubiquitin.

2001 • 310 citations

Characterization of Two Polyubiquitin Binding Sites in the 26 S Protease Subunit 5a

1998 • 307 citations

STAM and Hrs Are Subunits of a Multivalent Ubiquitin-binding Complex on Early Endosomes

2003 • 306 citations

Structure and functional interactions of the Tsg101 UEV domain

2002 • 294 citations

Monoubiquitin carries a novel internalization signal that is appended to activated receptors

2000 • 291 citations

Molecular Insights into Polyubiquitin Chain Assembly

2001 • 289 citations

Automated structure solution, density modification and model building

2002 • 287 citations

Regulation of Receptor Tyrosine Kinase Signaling by Endocytic Trafficking

2001 • 269 citations

Mechanisms of enveloped RNA virus budding

2002 • 263 citations

Interaction of hHR23 with S5a

1999 • 261 citations

Molecular recognition in the HIV-1 capsid/cyclophilin A complex 1 1Edited by J. A. Wells

1997 • 255 citations

Distinct Functional Surface Regions on Ubiquitin

2001 • 241 citations

Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.

1996 • 240 citations

Structural Studies of the Interaction between Ubiquitin Family Proteins and Proteasome Subunit S5a

2002 • 218 citations

CLAMP©: a biosensor kinetic data analysis program

1998 • 217 citations

Ubiquitin‐associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi‐ubiquitin chain assembly

2001 • 211 citations

eps15 and eps15R are essential components of the endocytic pathway.

1997 • 201 citations

The Epsins Define a Family of Proteins That Interact with Components of the Clathrin Coat and Contain a New Protein Module

1999 • 186 citations

Hrs Is Associated with STAM, a Signal-transducing Adaptor Molecule

1997 • 185 citations

SNAREs and the specificity of membrane fusion

2001 • 175 citations

Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late‐Endosome/Vacuole

2001 • 151 citations

Tyrosine Phosphorylation of Eps15 Is Required for Ligand-Regulated, but Not Constitutive, Endocytosis

2000 • 135 citations

Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction

2000 • 134 citations

Self-Associating Systems in the Analytical Ultracentrifuge

2004 • 125 citations

Association and Colocalization of Eps15 with Adaptor Protein-2 and Clathrin

1997 • 124 citations

Epidermal Growth Factor Induces Ubiquitination of Eps15

1997 • 110 citations

Ubiquitin Signals Protein Trafficking via Interaction with a Novel Ubiquitin Binding Domain in the Membrane Fusion Regulator, Vps9p

2003 • 105 citations

The breast cancer gene product TSG101: a regulator of ubiquitination?

1997 • 89 citations

Identification of homer as a homologue of the Wiskott-Aldrich Syndrome protein suggests a receptor-binding function for WH1 domains

1997 • 89 citations

Late Assembly Domain Function Can Exhibit Context Dependence and Involves Ubiquitin Residues Implicated in Endocytosis

2002 • 81 citations

A ubiquitin-interacting motif from Hrs binds to and occludes the ubiquitin surface necessary for polyubiquitination in monoubiquitinated proteins

2002 • 65 citations

Hrs-2 Regulates Receptor-mediated Endocytosis via Interactions with Eps15

2000 • 62 citations

Construct for High-Level Expression and Low Misincorporation of Lysine for Arginine During Expression of pET-Encoded Eukaryotic Proteins in Escherichia coli

1999 • 53 citations

Interlayer Porosity in Montmorillonite Intercalated with Keggin-like Cation Studied by Molecular Mechanics Simulation

1997 • 31 citations