Factors in hydrazine formation from isoniazid by paediatric and adult tuberculosis patients

Rifampin-induced release of hydrazine from isoniazid. A possible cause of hepatitis during treatment of tuberculosis with regimens containing isoniazid and rifampin.

1986 • 115 citations

Plasma Hydrazine Concentrations in Man after Isoniazid and Hydralazine Administration

1985 • 97 citations

Risk Factors for Isoniazid (INH)-Induced Liver Dysfunction

1981 • 87 citations

The determination of isoniazid and its metabolites acetylisoniazid, monoacetylhydrazine, diacetylhydrazine, isonicotinic acid and isonicotinylglycine in serum and urine

1972 • 70 citations

Cerebrospinal Fluid Isoniazid Concentrations in Children With Tuberculous Meningitis: The Influence of Dosage and Acetylation Status

1992 • 43 citations

Is Isoniazid - Hepatotoxicity Induced by the Metabolite, Hydrazine?

1983 • 40 citations

Oxidation of hydrazine metabolites formed from isoniazid

1985 • 36 citations

Hepatic Toxicity During Chemotherapy for Severe Tuberculous Meningitis

1987 • 31 citations

Increased urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid

1987 • 26 citations

Acetylation of acetylhydrazine, the toxic metabolite of isoniazid, in humans. Inhibition by concomitant administration of isoniazid.

1987 • 22 citations

Determination of the acetylator phenotype from the ratio of the urinary excretion of acetylisoniazid to acid-labile isoniazid: a study in finnish lapland

1973 • 20 citations

Microanalysis of plasma isoniazid and acetylisoniazid by high performance liquid chromatography

1984 • 19 citations

Microdosage de l'isoniazide et de l'acetylisoniazide plasmatiques par chromatographie liquide à haute performance

1984 • 19 citations

A Study of the Effects of Rifampicin on Isoniazid Metabolism in Human Volunteer Subjects

1985 • 18 citations

Acetylator phenotype and metabolic disposition of isoniazid in japanese patients with systemic lupus erythematosus

1981 • 17 citations

Self-induction of rifampicin metabolism in man.

1985 • 14 citations

Isoniazid-related hepatotoxicity: A study of the effect of rifampicin administration on the metabolism of acetylisoniazid in man

1989 • 14 citations

Promutagenic Alkyl Lesions are Induced in the Tissue DNA of Animals Treated with Isoniazid

1988 • 12 citations

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