Weaver Gene Expression in Central Nervous System

Handbook of Chemical Neuroanatomy

1986 • 4,276 citations

Genetic variants and strains of the laboratory mouse

1990 • 1,519 citations

Physiological and Biochemical Aspects of Nervous Integration

1968 • 740 citations

Immobility induced by forced swimming in rats: Effects of agents which modify central catecholamine and serotonin activity

1979 • 576 citations

Sequence of developmental abnormalities leading to granule cell deficit in cerebellar cortex of weaver mutant mice

1973 • 531 citations

Catalog of the Neurological Mutants of the Mouse

1965 • 520 citations

The pre- and postnatal development of the dopaminergic cell groups in the ventral mesencephalon and the dopaminergic innervation of the striatum of the rat

1988 • 499 citations

Dopamine in dendrites of substantia nigra neurons: suggestions for a role in dendritic terminals

1975 • 482 citations

Organization of cerebellar cortex secondary to deficit of granule cells in weaver mutant mice

1973 • 472 citations

Morphological Development of the Rat Cerebellum and Some of Its Mechanisms

1982 • 360 citations

Genetic Variants and Strains of the Laboratory Mouse

1990 • 327 citations

Anatomical, physiological and biochemical studies of the cerebellum from mutant mice. II. Morphological study of cerebellar cortical neurons and circuits in the weaver mouse

1975 • 276 citations

Abnormal rate of granule cell migration in the cerebellum of “weaver” mutant mice

1972 • 221 citations

Dopamine deficiency in the weaver mutant mouse

1982 • 215 citations

Time of Origin of Neurons in the Brain Stem of the Mouse

1973 • 197 citations

Astrotactin: a novel neuronal cell surface antigen that mediates neuron-astroglial interactions in cerebellar microcultures

1988 • 192 citations

Bergmann fibers and granular cell migration in the cerebellum of homozygous weaver mutant mouse

1974 • 191 citations

Mesencephalic dopamine cell deficit involves areas A8, A9 and A10 in weaver mutant mice

1988 • 173 citations

Localization of the mRNA for the dopamine D2 receptor in the rat brain by in situ hybridization histochemistry.

1989 • 167 citations

Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

1989 • 164 citations

CEREBELLAR ALTERATIONS IN THE WEAVER MOUSE

1973 • 158 citations

Purkinje Cell Ontogeny: Formation and Maintenance of Spines

1978 • 156 citations

Sulfonylurea binding sites associated with ATP-regulated K+ channels in the central nervous system: autoradiographic analysis of their distribution and ontogenesis, and of their localization in mutant mice cerebellum

1990 • 152 citations

Weaver mouse cerebellar granule neurons fail to migrate on wild-type astroglial processes in vitro

1986 • 137 citations

Weaver mutation has differential effects on the dopamine-containing innervation of the limbic and nonlimbic striatum

1984 • 137 citations

Dopamine depletion, stimulation or blockade in the rat disrupts spatial navigation and locomotion dependent upon beacon or distal cues

1985 • 131 citations

Granule cell as a site of gene action in the weaver mouse cerebellum: evidence from heterozygous mutant chimeras

1982 • 125 citations

Molecular Genetic Neuroscience

1983 • 121 citations

PRIMARY DEGENERATION OF THE GRANULAR LAYER OF THE CEREBELLUM: AN UNUSUAL FORM OF FAMILIAL CEREBELLAR ATROPHY OCCURRING IN EARLY LIFE

1940 • 115 citations

Conserved chromosomal positions of dual domains of the ets protooncogene in cats, mice, and humans.

1986 • 114 citations

The development of bergmann glia in mutant mice with cerebellar malformations: Reeler, staggerer and weaver. Immunofluorescence study with antibodies to the glial fibrillary acidic protein

1974 • 105 citations

A qualitative and quantitative light microscopic study of the inferior olivary complex of normal, reeler, and weaver mutant mice

1985 • 104 citations

Visualization of a dopamine D1 receptor mRNA in human and rat brain

1991 • 104 citations

Multiple innervation of purkinje cells by climbing fibers in the cerebellum of the weaver mutant mouse

1976 • 104 citations

Extent of multiple innervation of purkinje cells by climbing fibers in the olivocerebellar system of weaver, reeler, and staggerer mutant mice

1982 • 103 citations

Dopaminergic cells align along radial glia in the developing mesencephalon of the rat

1990 • 103 citations

Dendritic abnormalities of Purkinje cells in the cerebellum of neurologic mutant mice (weaver and staggerer).

1975 • 103 citations

The Purkinje cell dendritic tree in mutant mouse cerebellum. A quantitative Golgi study of Weaver and Staggerer mice

1978 • 101 citations

Fate of presynaptic afferents to Purkinje cells in the adult nervous mutant mouse: A model to study presynaptic stabilization

1979 • 99 citations

Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. I. Gradients and compartments

1990 • 98 citations

The weaver granuloprival phenotype is due to intrinsic action of the mutant locus in granule cells: Evidence from homozygous weaver chimeras

1989 • 97 citations

The postnatal development of the dopamine-containing innervation of dorsal and ventral striatum: effects of the weaver gene.

1987 • 82 citations

Performance of normal and neurological mutant mice on radial arm maze and active avoidance tasks

1986 • 81 citations

Expression of the weaver gene in dopamine-containing neural systems is dose-dependent and affects both striatal and nonstriatal regions

1986 • 76 citations

Genetic mapping of ?Lubag? (X-linked dystonia-parkinsonism) in a filipino kindred to the pericentromeric region of the X chromosome

1991 • 75 citations

Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice

1990 • 67 citations

Defects in specific associations between astroglia and neurons occur in microcultures of weaver mouse cerebellar cells

1984 • 66 citations

Early familial cerebellar degeneration; report of 3 cases in one family.

1950 • 64 citations

Selective loss of monoaminergic neurons in weaver mutant mice— an immunocytochemical study

1987 • 63 citations

The mouse neurological mutant weaver maps within the region of chromosome 16 that is homologous to human chromosome 21

1989 • 63 citations

Genetic mapping of <i>Prm-1, Igl-1, Smst, Mtv-6, Sod-1,</i> and <i>Ets-2</i>and localization of the Down syndrome region on mouse chromosome 16

1987 • 62 citations

Contents of serotonin, norepinephrine and dopamine in the cerebrum of the ‘staggerer’, ‘weaver’ and ‘nervous’ neurologically mutant mice

1977 • 60 citations

Membrane specializations of dentritic spines and glia in the weaver mouse cerebellum: a freeze-fracture study.

1976 • 58 citations

CEREBELLAR HYPOPLASIA ASSOCIATED WITH SYSTEMIC DEGENERATION IN EARLY LIFE

1958 • 57 citations

Mutant mice and the formation of cerebellar circuitry

1980 • 57 citations

Motor abnormalities in weaver mutant mice

1987 • 55 citations

Genetic linkage in the mouse of genes involved in down syndrome and Alzheimer's disease in man

1987 • 52 citations

Patterns of cell and fiber vulnerability in the mesostriatal system of the mutant mouse weaver. II. High affinity uptake sites for dopamine

1990 • 52 citations

Navigational deficits in weaver mutant mice

1986 • 51 citations

EARLY FAMILIAL CEREBELLAR DEGENERATION*

1950 • 50 citations

Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake

1989 • 50 citations

Transplantation of ventral mesencephalic anlagen to hosts with genetic nigrostriatal dopamine deficiency.

1986 • 50 citations

Molecular genetic neuroscience

1982 • 48 citations

The mouse homolog of the human amyloid β protein (AD-AP) gene is located on the distal end of mouse chromosome 16: Further extension of the homology between human chromosome 21 and mouse chromosome 16

1987 • 44 citations

STUDIES ON THE PURKINJE CELL DEGENERATION (pcd) MUTANT: PRIMARY PATHOLOGY AND TRANSNEURONAL CHANGES

1978 • 43 citations

Synaptic connectivity of tyrosine hydroxylase immunoreactive nerve terminals in the striatum of normal, heterozygous and homozygous weaver mutant mice

1988 • 41 citations

The climbing fiber system in the Weaver mutant

1977 • 40 citations

ATP‐Dependent Glutamate Uptake into Synaptic Vesicles from Cerebellar Mutant Mice

1988 • 40 citations

The dendritic dopamine projection of the substantia nigra: phenotypic denominator of weaver gene action in hetero- and homozygosity

1989 • 40 citations

Tonic/clonic seizures in a mouse mutant carrying the weaver gene

1989 • 37 citations

Substantia nigra-mediated anticonvulsant action: a possible role of a dopaminergic component

1990 • 34 citations

Effect of the weaver (wv) mutation on cerebellar neuron differentiation

1985 • 33 citations

Transiently expressed, neural-specific molecule associated with premigratory granule cells in postnatal mouse cerebellum

1989 • 32 citations

Striatal dopamine innervation and receptor density: regional effects of the weaver mutation

1989 • 30 citations

Autosomal Recessive Cerebellar Hypoplasia

1989 • 30 citations

Dopamine D2 receptors increase in the dorsolateral striatum of weaver mutant mice

1987 • 29 citations

Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft

1990 • 25 citations

Transplantation of cerebellar anlagen to hosts with genetic cerebellocortical atrophy

1987 • 25 citations

Age-related changes in striatal dopamine D2 receptor binding in weaver mice and effects of ventral mesencephalic grafts

1990 • 24 citations

Dopamine D1 binding sites in the striatum of the mutant mouse weaver

1989 • 24 citations

Neuroanatomical substrate of behavioural impairment in weaver mutant mice

1987 • 24 citations

Delayed spontaneous alternation in weaver mutant mice

1986 • 24 citations

Concordant primary atrophy of the cerebellar granules in monozygotic twins

1954 • 24 citations

Reduction of nerve growth factor level in the brain of genetically ataxic mice (weaver, reeler)

1990 • 24 citations

On the Relationship Between Human and Experimental Granule Cell Type Cerebellar Degeneration

1973 • 22 citations

Autoradiographic visualization of a calcium channel antagonist, [125I]ω-conotoxin GVIA, binding site in the brains of normal and cerebellar mutant mice (pcd andweaver)

1989 • 22 citations

Effect of the weaver (wv) mutation on cerebellar neuron differentiation

1985 • 22 citations

Horizontal optokinetic ocular nystagmus in wildtype (B6CBA+/+) and weaver mutant mice

1988 • 22 citations

Reinstatement of synaptic connectivity in the striatum of weaver mutant mice following transplantation of ventral mesencephalic anlagen

1988 • 21 citations

Altered Expression of the D1.1 Ganglioside in the Cerebellum of the Weaver Mouse

1988 • 20 citations

Exploration of a hole-board matrix in nervous mutant mice

1985 • 20 citations

Neuronal differentiation in cultures of weaver (wv) mutant mouse cerebellum

1981 • 19 citations

Primary degeneration of the granular layer of the cerebellum (Norman type)

1987 • 17 citations

Acquired immobility response in weaver mutant mice

1986 • 17 citations

Saxitoxin-sensitive Na+ channels: presynaptic localization in cerebellum and hippocampus of neurological mutant mice

1990 • 14 citations

Changes in the pattern of expression of pp^60c‐src in cerebellar mutants of mice

1987 • 13 citations

Postnatal development of the wild-type and weaver cerebellum after embryonic administration of propylthiouracil (PTU)

1990 • 12 citations

Chapter 21 Dopamine neurone grafting to the weaver mouse neostriatum

1990 • 11 citations

Possible Synapse Formation by Embryonic Cerebellar Tissue Grafted into the Cerebellum of the Weaver Mutant Mouse

1988 • 8 citations

Congenital Granuloprival Hypoplasia of Cerebellar and Hippocampal Cortex

1987 • 7 citations

Layer-specific innervation of the dopamine-deficient frontal cortex in weaver mutant mice by grafted mesencephalic dopaminergic neurones

1988 • 6 citations