PROTEOLYTIC ACTIVITY AND BASIC PROTEIN LOSS IN AND AROUND MULTIPLE SCLEROSIS PLAQUES: COMBINED BIOCHEMICAL AND EIISTOCHEMICAL OBSERVATIONS

Protides of the Biological Fluids

1969 • 1,623 citations

HISTOCHEMICAL METHODS FOR ACID PHOSPHATASE USING HEXAZONIUM PARAROSANILIN AS COUPLER

1962 • 1,599 citations

Lipid composition of the normal human brain: gray matter, white matter, and myelin

1965 • 759 citations

Factors governing the validity of staining methods for enzymes, and their bearing upon the Gomori acid phosphatase technique*1

1959 • 318 citations

Thin-layer chromatography of the phosphoinositides

1968 • 256 citations

Myo-inositol Phosphates Obtained by Alkaline Hydrolysis of Beef Brain Phosphoinositide

1961 • 217 citations

Allergic encephalomyelitis: the physico-chemical properties of the basic protein encephalitogen from bovine spinal cord

1969 • 173 citations

Separation of acid and neutral proteinases of brain

1965 • 128 citations

PROTEIN BREAKDOWN IN THE BRAIN. SUBCELLULAR DISTRIBUTION AND PROPERTIES OF NEUTRAL AND ACID PROTEINASES

1963 • 109 citations

Increased protease activity and changes in basic proteins and lipids in multiple sclerosis plaques

1970 • 106 citations

Complete Characterization of the Myo-inositol Polyphosphates from Beef Brain Phosphoinositide

1961 • 102 citations

Proteolysis and myelin breakdown: a review of recent histochemical and biochemical studies

1969 • 101 citations

THE HISTOCHEMICAL DEMONSTRATION OF PROTEASE BY A GELATIN-SILVER FILM SUBSTRATE

1961 • 93 citations

Complex-formation between triphosphoinositide and experimental allergic encephalitogenic protein

1969 • 89 citations

Biochemical maturation of the central nervous system

1969 • 87 citations

Degradation of encephalitogen by purified brain acid proteinase

1968 • 83 citations

THE LIPID COMPOSITION OF MYELIN FROM BRAIN AND PERIPHERAL NERVE

1965 • 74 citations

PHYSICAL PROPERTIES OF THE BOVINE ENCEPHALITOGENIC PROTEIN; MOLECULAR WEIGHT AND CONFORMATION¹

1970 • 73 citations

The relationship between enzyme activity and neuroglia in plaques of multiple sclerosis

1963 • 72 citations

PROTEINS, LIPID-PROTEIN DISSOCIATION AND PROTEINASE ACTIVITY IN WALLERIAN DEGENERATION

1961 • 70 citations

Isolation and Characterization of an Active Fragment from Enzymatic Degradation of Encephalitogenic Protein

1968 • 59 citations

ACID PROTEINASE ACTIVITY OF WHITE MATTER AND PLAQUES IN MULTIPLE SCLEROSIS

1970 • 56 citations

Proteinase activity of myelin

1969 • 54 citations

Histochemistry of myelin. VIII. Proteolytic activity around multiple sclerosis plaques

1970 • 47 citations

Basic proteins from the acidic extract of bovine spinal cord

1966 • 46 citations

Enzyme Histochemical Studies in Multiple Sclerosis

1961 • 43 citations

Pathogenesis and Etiology of Demyelinating Diseases

1970 • 43 citations

HISTOCHEMISTRY OF MYELIN V. TRYPSIN-DIGESTIBLE AND TRYPSIN-RESISTANT PROTEINS

1968 • 41 citations

Lipid Histochemistry

1969 • 37 citations

HISTOCHEMISTRY OF MYELIN. XIII DIGESTION OF BASIC PROTEIN OUTSIDE ACUTE PLAQUES OF MULTIPLE SCLEROSIS

1971 • 35 citations

RESEARCH IN MULTIPLE SCLEROSIS

1971 • 31 citations

Histochemistry of myelin. IX. Neutral and acid proteinases in early Wallerian degeneration

1970 • 28 citations

Histochemistry of myelin. XI. Loss of basic protein in early myelin breakdown and multiple sclerosis plaques

1970 • 22 citations

Lysosomes

1969 • 11 citations

Quantitative determination of γ-globulin in human sera by column chromatography

1968 • 8 citations

Quantitative determination of γ-globulin in the human sera by column chromatography

1968 • 7 citations

The PASDORO method for simultaneously demonstrating DNA and lipids in the brain

1970 • 3 citations

CHEMICAL AND ENZYMATIC STUDIES ON THE COMPOSITION OF THE WHITE MATTER IN MULTIPLE-SCLEROSIS BRAINS

2009 • 2 citations