Regulation of the actin cycle in vivo by actin filament severing

Cell Migration: A Physically Integrated Molecular Process

1996 • 3,909 citations

The interaction of Arp2/3 complex with actin: Nucleation, high affinity pointed end capping, and formation of branching networks of filaments

1998 • 1,388 citations

Arp2/3 Complex and Actin Depolymerizing Factor/Cofilin in Dendritic Organization and Treadmilling of Actin Filament Array in Lamellipodia

1999 • 1,150 citations

The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress

1981 • 1,123 citations

Actin Depolymerizing Factor (ADF/Cofilin) Enhances the Rate of Filament Turnover: Implication in Actin-based Motility

1997 • 1,028 citations

Proteins of the ADF/Cofilin Family: Essential Regulators of Actin Dynamics

1999 • 1,004 citations

Models of dispersal in biological systems

1988 • 876 citations

Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments.

1986 • 828 citations

Actin microfilament dynamics in locomoting cells

1991 • 789 citations

Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex

1999 • 771 citations

Head to tail polymerization of actin

1976 • 692 citations

Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

1995 • 665 citations

Gelsolin, a Multifunctional Actin Regulatory Protein

1999 • 589 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin

1995 • 437 citations

Biology of Endothelial Cells

1984 • 426 citations

Mechanisms of actin rearrangements mediating platelet activation.

1992 • 413 citations

Gelsolin is a downstream effector of rac for fibroblast motility

1998 • 267 citations

The ADF/Cofilin Proteins: Stimulus-responsive Modulators of Actin Dynamics

1995 • 255 citations

Characterization of actin filament severing by actophorin from Acanthamoeba castellanii.

1991 • 247 citations

Actin filament organization in the fish keratocyte lamellipodium.

1995 • 236 citations

Synergy between Actin Depolymerizing Factor/Cofilin and Profilin in Increasing Actin Filament Turnover

1998 • 218 citations

Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization.

1981 • 217 citations

Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recovery

1982 • 206 citations

Control of actin dynamics

1998 • 206 citations

Control of Actin Dynamics in Cell Motility

1999 • 202 citations

Unpolymerized actin in fibroblasts and brain

1976 • 186 citations

Stabilization and the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition.

1981 • 184 citations

Isolation and characterization of a regulated form of actin depolymerizing factor

1993 • 178 citations

Simultaneous Measurements of Actin Filament Turnover, Filament Fraction, and Monomer Diffusion in Endothelial Cells

1998 • 169 citations

Comparison of actin and cell surface dynamics in motile fibroblasts.

1992 • 146 citations

The Submicroscopic Properties of Cytoplasm as a Determinant of Cellular Function

1988 • 143 citations

Kinetic analysis of F-actin depolymerization in polymorphonuclear leukocyte lysates indicates that chemoattractant stimulation increases actin filament number without altering the filament length distribution.

1991 • 129 citations

Identification of Enhanced Serine Kinase Activity in Insulin Resistance

1999 • 107 citations

Gelsolin and functionally similar actin-binding proteins are regulated by lysophosphatidic acid

1998 • 98 citations

Gelsolin-actin interaction and actin polymerization in human neutrophils.

1990 • 81 citations

Microfilament-based motility in non-muscle cells

1989 • 70 citations

In vitro reendothelialization. Microfilament bundle reorganization in migrating porcine endothelial cells.

1984 • 69 citations

Interpreting photoactivated fluorescence microscopy measurements of steady-state actin dynamics

1995 • 53 citations

Measuring actin dynamics in endothelial cells

1998 • 25 citations

Endothelial cell motility

1984 • 15 citations

Crystallization of actophorin, an actin filament-severing protein from Acanthamoeba.

1988 • 7 citations