Phosphorylation and dephosphorylation of human promyelocytic leukemia cell (HL-60) proteins by tumor promoter

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1983 • 1,304 citations

Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.

1983 • 890 citations

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity.

1980 • 853 citations

C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

1984 • 715 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Induction of Differentiation in Human Promyelocytic Leukemia Cells by Tumor Promoters

1979 • 594 citations

Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine

1980 • 510 citations

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Epidermal growth factor stimulates phosphorylation in membrane preparations in vitro

1978 • 448 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Specific high affinity cell membrane receptors for biologically active phorbol and ingenol esters

1980 • 274 citations

Phorbol ester-induced differentiation of chronic lymphocytic leukaemia cells

1980 • 258 citations

Phospholipid-sensitive Ca2+-dependent protein phosphorylation system in various types of leukemic cells from human patients and in human leukemic cell lines HL60 and K562, and its inhibition by alkyl-lysophospholipid.

1983 • 207 citations

1α,25-Dihyroxyvitamin D3 induces differentiation of human promyelocytic leukemia cells (HL-60) into monocyte-macrophages, but not into granulocytes

1983 • 206 citations

In Vitro Studies on the Mode of Action of the Phorbol Esters, Potent Tumor Promoters, Part 2

1981 • 168 citations

Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1,25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate.

1983 • 153 citations

A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product

1979 • 146 citations

Rapid protein phosphorylation induced by phorbol ester in HL-60 cells. Unique alkali-stable phosphorylation of a 17,000-dalton protein detected by two-dimensional gel electrophoresis.

1983 • 133 citations

Current concepts and controversies in chemical carcinogenesis

1981 • 126 citations

Differentiation of human leukemias in response to 12-0- tetradecanoylphorbol-13-acetate in vitro

1980 • 121 citations

Kinetics of appearance of differentiation-associated characteristics in ML-1, a line of human myeloblastic leukemia cells, after treatment with 12-O-tetradecanoylphorbol-13-acetate, dimethyl sulfoxide or 1-beta-D-arabinofuranosylcytosine.

1982 • 120 citations

Regulation of acid phosphatase activity in human promyelocytic leukemic cells induced to differentiate in culture.

1979 • 56 citations

Tumour Promoters Induce Macrophage Differentiation in Human Myeloid Cells from Patients with Acute and Chronic Myelogenous Leukaemia

1981 • 47 citations

Macrophage differentiation of human precursor B-cell line by phorbol ester and colony-stimulating factor

1982 • 21 citations

Solid-state spectroscopy

1980 • 5 citations