Impaired Receptor Binding and Activation Associated with a Human Prostacyclin Receptor Polymorphism

Prostanoid Receptors: Structures, Properties, and Functions

1999 • 2,395 citations

dbSNP—Database for Single Nucleotide Polymorphisms and Other Classes of Minor Genetic Variation

1999 • 782 citations

Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

1997 • 775 citations

Enhanced Myocardial Function in Transgenic Mice Overexpressing the β ₂ -Adrenergic Receptor

1994 • 745 citations

Asthma exacerbations during long term beta agonist use: influence of beta 2 adrenoceptor polymorphism

2000 • 351 citations

The Ile164 beta2-adrenergic receptor polymorphism adversely affects the outcome of congestive heart failure.

1998 • 350 citations

Inhaled Iloprost To Treat Severe Pulmonary Hypertension: An Uncontrolled Trial

2000 • 281 citations

Effect of orally active prostacyclin analogue on survival of outpatients with primary pulmonary hypertension

1999 • 208 citations

Polymorphism in the β ₁ -Adrenergic Receptor Gene and Hypertension

2001 • 185 citations

Polymorphisms of the β₂-Adrenergic Receptor and Asthma

1997 • 161 citations

Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s).

2000 • 158 citations

Overexpression of Gs alpha protein in the hearts of transgenic mice.

1995 • 140 citations

The molecular basis of nephrogenic diabetes insipidus

1998 • 134 citations

Functional Analysis of the Human D2 Dopamine Receptor Missense Variants

1996 • 125 citations

Genetic Variations and Polymorphisms of G Protein-Coupled Receptors: Functional and Therapeutic Implications

2001 • 99 citations

Novel Mutations of the Endothelin B Receptor Gene in Patients with Hirschsprung's Disease and Their Characterization

1998 • 93 citations

Internalization and Sequestration of the Human Prostacyclin Receptor

2000 • 88 citations

Structure and function in rhodopsin: Packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled

1997 • 87 citations

The Prostacyclin Receptor Is Isoprenylated

1999 • 78 citations

Glycosylation of the human prostacyclin receptor: role in ligand binding and signal transduction.

2001 • 55 citations

Dopamine D4 receptor variant in Africans, D4Valine194Glycine, is insensitive to dopamine and clozapine: Report of a homozygous individual

1996 • 52 citations

Identification of Domains Conferring Ligand Binding Specificity to the Prostanoid Receptor

1997 • 45 citations

Mutations in the vasopressin V2 receptor gene in families with nephrogenic diabetes insipidus and functional expression of the Q-2 mutant.

1994 • 42 citations

Amino Acid Residues Conferring Ligand Binding Properties of Prostaglandin I and Prostaglandin D Receptors

2000 • 33 citations

Genetic Polymorphisms in Drug-Metabolizing Enzymes and Drug Targets

2001 • 18 citations

Factors affecting prostacyclin receptor agonist efficacy in different cell types

2001 • 15 citations