The anabolic effect of human PTH (1–34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate—is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

1983 • 1,535 citations

Modifications of a specific assay for hydroxyproline in urine

1967 • 1,091 citations

Bone and Mineral Research

1990 • 1,070 citations

Parathyroid Hormone Stimulates the Bone Apposition Rate Independently of Its Resorptive Action: Differential Effects of Intermittent and Continuous Administration*

1982 • 620 citations

Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial.

1980 • 587 citations

Insulin-like growth factor I mediates selective anabolic effects of parathyroid hormone in bone cultures.

1989 • 541 citations

Urinary excretion of pyridinium crosslinks: a new marker of bone resorption in metabolic bone disease

1990 • 431 citations

Restoration of spinal bone in osteoporotic men by treatment with human parathyroid hormone (1–34) and 1,25-dihydroxyvitamin D

1986 • 351 citations

The Histomorphometry of Bone in Primary Hyperparathyroidism: Preservation of Cancellous Bone Structure*

1990 • 329 citations

Parathyroid hormone stimulates bone formation and resorption in organ culture: evidence for a coupling mechanism.

1981 • 260 citations

Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in bone marrow

1994 • 248 citations

Increased trabecular bone mass in rats treated with human synthetic parathyroid hormone

1984 • 219 citations

Parathyroid hormone receptor in intact embryonic chicken bone: characterization and cellular localization.

1982 • 209 citations

Human parathyroid hormone-(1-34) prevents bone loss and augments bone formation in sexually mature ovariectomized rats

1990 • 206 citations

Effects of Two Treatment Regimes with Synthetic Human Parathyroid Hormone Fragment on Bone Formation and the Tissue Balance of Trabecular Bone in Greyhounds

1983 • 194 citations

Assessment of bone turnover in postmenopausal osteoporosis by measurement of serum bone Gla-protein.

1983 • 189 citations

Loss of cancellous bone mass and connectivity in ovariectomized rats can be restored by combined treatment with parathyroid hormone and estradiol.

1993 • 188 citations

PREVENTION OF POSTMENOPAUSAL BONE LOSS BY TILUDRONATE

1989 • 182 citations

EFFECT OF DICHLOROMETHYLENE DIPHOSPHONATE IN PAGET'S DISEASE OF BONE AND IN HYPERCALCÆMIA DUE TO PRIMARY HYPERPARATHYROIDISM OR MALIGNANT DISEASE

1980 • 179 citations

An evaluation of several biochemical markers for bone formation and resorption in a protocol utilizing cyclical parathyroid hormone and calcitonin therapy for osteoporosis.

1993 • 164 citations

Trabecular bone remodeling and balance in primary hyperparathyroidism

1986 • 141 citations

Resorption is not essential for the stimulation of bone growth by hPTH-(1-34) in rats in vivo

1989 • 129 citations

Effect of human parathyroid hormone (PTH(1-34)) on experimental osteopenia of rats induced by ovariectomy.

1988 • 118 citations

Treatment of osteoporosis with human parathyroid peptide and observations on effect of sodium fluoride.

1990 • 114 citations

Glucocorticoid-induced inhibition of osteoblastic bone formation in ewes: A biochemical and histomorphometric study

1993 • 112 citations

Comparison of the Anabolic Effects of Synthetic Parathyroid Hormone-Related Protein (PTHrP) 1–34 and PTH 1–34 on Bone in Rats*

1989 • 105 citations

Bone densitometric and histomorphometric responses to sequential human parathyroid hormone (1–38) and salmon calcitonin in osteoporotic patients

1991 • 101 citations

Histomorphometry of bone.

1983 • 98 citations

Parathyroid hormone modulates transforming growth factor beta activity and binding in osteoblast-enriched cell cultures from fetal rat parietal bone.

1988 • 98 citations

Effects of combined and separate intermittent administration of low-dose human parathyroid hormone fragment (1?34) and 17?-estradiol on bone histomorphometry in ovariectomized rats with established osteopenia

1992 • 96 citations

Estimation of the three-dimensional wall thickness of completed remodeling sites in iliac trabecular bone

1982 • 86 citations

Effects of combined prostaglandin and alendronate treatment on the histomorphometry and biomechanical properties of bone in ovariectomized rats

1993 • 83 citations

Evidence for the coupling of bone formation to bone resorption in vitro

1980 • 78 citations

The relationship between changes in femoral bone density and calcium balance in patients with involutional osteoporosis treated with human parathyroid hormone fragment (hPTH 1–34)

1981 • 76 citations

IGF-I and pamidronate increase bone mineral density in ovariectomized adult rats

1993 • 71 citations

Restoration of axial and appendicular bone volumes by h-PTH(1–34) in parathyroidectomized and osteopenic rats

1990 • 70 citations

Intermethod variation in bone histomorphometry: Comparison between manual and computerized methods applied to iliac bone biopsies

1985 • 59 citations

Dose effects on ewe bone remodeling of short-term sodium fluoride administration — A histomorphometric and biochemical study

1991 • 49 citations

Oral tiludronate: Pharmacological properties and potential usefulness in Paget's disease of bone and osteoporosis

1992 • 40 citations

Specific radioimmunoassay for ovine bone gla-protein (osteocalcin)

1988 • 23 citations

Bone histomorphometry and serum bone gla-protein in the diagnosis of primary hyperparathyroidism

1986 • 18 citations

Bone and Mineral Research, Annual 1: A Yearly Survey of Developments in the Field of Bone and Mineral Metabolism

1983 • 17 citations

Human Parathyroid Peptide (HPTH 1–34) Treatment Increases the Mean Wall Thickness of Iliac Trabecular Packets of New Bone in Patients with Crush Fracture Osteoporosis

1988 • 6 citations

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