Cardiac Effects of Ebastine and Other Antihistamines in Humans

Terfenadine-Ketoconazole Interaction

1993 • 654 citations

Rate-corrected QT interval: Techniques and limitations

1993 • 403 citations

Diurnal pattern of QTc interval: How long is prolonged?

1996 • 316 citations

Cardiac Actions of Antihistamines

1996 • 261 citations

Variability of the QT measurement in healthy men, with implications for selection of an abnormal QT value to predict drug toxicity and proarrhythmia

1991 • 186 citations

Hydrolysis of carbonates, thiocarbonates, carbamates, and carboxylic esters of alpha-naphthol, beta-naphthol, and p-nitrophenol by human, rat, and mouse liver carboxylesterases.

1993 • 91 citations

Variability of the QTc interval: Impact on defining drug effect and low-frequency cardiac event

1993 • 83 citations

Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects.

1996 • 75 citations

The clinical safety of H₁‐receptor antagonists: An EAACI position paper*

1996 • 74 citations

Polyanhydride microspheres that display near-constant release of water-soluble model drug compounds.

1993 • 68 citations

A review of the cardiac systemic side‐effects of antihistamines: ebastine

1999 • 47 citations

Preclinical In Vitro Cardiac Electrophysiology

1999 • 43 citations

Co‐administration of ketoconazole with H₁‐antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects

2005 • 42 citations

Effects of H1 Antihistamines on Animal Models of QTc Prolongation

1999 • 23 citations

Comparative effects of nonsedating histamine H1 receptor antagonists, ebastine and terfenadine, on human Kv1.5 channels

1997 • 22 citations

Pharmacokinetics and Electrocardiographic Effect of Ebastine in Young Versus Elderly Healthy Subjects

1998 • 17 citations

Effects of histamine H1 receptor antagonists on action potentials in guinea-pig isolated papillary muscles.

1996 • 13 citations

Suppression of the skin reaction to histamine by ebastine.

1995 • 9 citations

THE EFFECT OF FOOD ON THE BIOAVAILABILITY OF EBASTINE

1997 • 8 citations

Safety of terfenadine and astemizole.

1992 • 5 citations