Dual Control of glut1 Glucose Transporter Gene Expression by Hypoxia and by Inhibition of Oxidative Phosphorylation

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

1995 • 5,971 citations

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

1992 • 2,420 citations

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1.

1994 • 1,821 citations

Fos and jun: The AP-1 connection

1988 • 1,597 citations

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.

1993 • 1,441 citations

Identification of p53 as a Sequence-Specific DNA-Binding Protein

1991 • 1,109 citations

Regulation of the Erythropoietin Gene: Evidence That the Oxygen Sensor Is a Heme Protein

1988 • 1,042 citations

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.

1991 • 932 citations

Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors

1986 • 883 citations

Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

1993 • 857 citations

Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells

1995 • 608 citations

Requirement for fos gene expression in the transcriptional activation of collagenase by other oncogenes and phorbol esters

1988 • 597 citations

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

1994 • 584 citations

Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences

1995 • 553 citations

Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein.

1986 • 550 citations

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.

1994 • 517 citations

Hypoxia Induces Vascular Endothelial Growth Factor in Cultured Human Endothelial Cells

1995 • 487 citations

Stabilization of Vascular Endothelial Growth Factor mRNA by Hypoxia and Hypoglycemia and Coregulation with Other Ischemia-Induced Genes

1995 • 453 citations

Mammalian Facilitative Glucose Transporter Family: Structure and Molecular Regulation

1992 • 419 citations

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism.

1993 • 411 citations

Family of Glucose-Transporter Genes: Implications for Glucose Homeostasis and Diabetes

1990 • 310 citations

Transformation of Rat Fibroblasts by FSV Rapidly Increases Glucose Transporter Gene Transcription

1987 • 286 citations

Growth factors rapidly induce expression of the glucose transporter gene.

1988 • 263 citations

Functional analysis of an oxygen-regulated transcriptional enhancer lying 3' to the mouse erythropoietin gene.

1991 • 260 citations

Membrane Transport: Its Relation to Cellular Metabolic Rates

1975 • 255 citations

Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxic cardiac myocytes

1993 • 206 citations

Stress-Activated Protein Kinases in Cardiovascular Disease

1996 • 204 citations

Regulation of glucose uptake by muscle. 3. The effects of insulin, anoxia, salicylate and 2:4-dinitrophenol on membrane transport and intracellular phosphorylation of glucose in the isolated rat heart

1959 • 203 citations

Hypoxia-induced Protein Binding to O2-responsive Sequences on the Tyrosine Hydroxylase Gene

1995 • 199 citations

Hypoxia induces glucose transporter expression in endothelial cells

1992 • 177 citations

Identification of two enhancer elements in the gene encoding the type 1 glucose transporter from the mouse which are responsive to serum, growth factor, and oncogenes.

1992 • 132 citations

Status of the transcription factors database (TFD)

1993 • 125 citations

Regulation of glucose transport and GLUT1 glucose transporter expression by O2 in muscle cells in culture

1992 • 120 citations

Hypoxia, a Novel Inducer of Acute Phase Gene Expression in a Human Hepatoma Cell Line

1995 • 119 citations

Platelet-derived growth factor regulates glucose transporter expression.

1988 • 117 citations

Rapid activation of GLUT-1 glucose transporter following inhibition of oxidative phosphorylation in clone 9 cells

1993 • 107 citations

Metabolic regulation of glucose transport

1993 • 86 citations

Enhancement of glucose transport in response to inhibition of oxidative metabolism: pre- and posttranslational mechanisms

1992 • 79 citations

Nuclear Signaling by Endothelin-1

1995 • 69 citations

The rat facilitated glucose transporter gene. Transformation and serum-stimulated transcription initiate from identical sites.

1988 • 66 citations

Enhanced glucose transport in response to inhibition of respiration in Clone 9 cells

1989 • 64 citations

Regulation of glucose transport activity and expression of glucose transporter mRNA by serum, growth factors and phorbol ester in quiescent mouse fibroblasts

1989 • 63 citations

Regulatory elements of the erythropoietin gene

1991 • 61 citations

Characterisation of functional domains within the mouse erythropoietin 3′ enhancer conveying oxygen-regulated responses in different cell lines

1994 • 46 citations

Induction of GLUT1 mRNA in response to inhibition of oxidative phosphorylation

1993 • 46 citations

Unresponsiveness of erythropoietin-producing cells to cyanide

1972 • 33 citations

Induction of GLUT-1 mRNA in response to inhibition of oxidative phosphorylation: role of increased [Ca2+]i

1996 • 22 citations

The role of hypoxia in renal production of erythropoietin.

1992 • 19 citations