Translocation of Analogues of the Antimicrobial Peptides Magainin and Buforin across Human Cell Membranes

Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor.

1987 • 2,216 citations

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters

2000 • 1,549 citations

Cationic peptides: a new source of antibiotics

1998 • 1,322 citations

Endocytosis

1997 • 1,263 citations

Amphipathic, α-helical antimicrobial peptides

2000 • 1,167 citations

Why and how are peptide–lipid interactions utilized for self-defense? Magainins and tachyplesins as archetypes

1999 • 984 citations

Mechanism of Action of the Antimicrobial Peptide Buforin II: Buforin II Kills Microorganisms by Penetrating the Cell Membrane and Inhibiting Cellular Functions

1998 • 853 citations

Cell-penetrating peptides

2000 • 767 citations

Trojan peptides: the penetratin system for intracellular delivery

1998 • 707 citations

An Antimicrobial Peptide, Magainin 2, Induced Rapid Flip-Flop of Phospholipids Coupled with Pore Formation and Peptide Translocation

1996 • 688 citations

Magainins as paradigm for the mode of action of pore forming polypeptides

1998 • 574 citations

Role of membranes in the activities of antimicrobial cationic peptides

2002 • 534 citations

Lipid translocation across the plasma membrane of mammalian cells

1999 • 437 citations

Cellular uptake of an α-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically

1998 • 436 citations

Possible Existence of Common Internalization Mechanisms among Arginine-rich Peptides

2002 • 429 citations

Molecular Basis for Membrane Selectivity of an Antimicrobial Peptide, Magainin 2

1995 • 398 citations

Antibiotic magainins exert cytolytic activity against transformed cell lines through channel formation.

1991 • 361 citations

Interactions of an antimicrobial peptide, magainin 2, with outer and inner membranes of Gram-negative bacteria

1997 • 349 citations

Translocation of a Channel-Forming Antimicrobial Peptide, Magainin 2, across Lipid Bilayers by Forming a Pore

1995 • 302 citations

A Novel Antimicrobial Peptide fromBufo bufo gargarizans

1996 • 286 citations

Orientational and Aggregational States of Magainin 2 in Phospholipid Bilayers

1994 • 264 citations

Anticancer efficacy of Magainin2 and analogue peptides.

1993 • 235 citations

The Antennapedia peptide penetratin translocates across lipid bilayers – the first direct observation

2000 • 231 citations

Different promoter usage and multiple transcription initiation sites of the interleukin‐1 receptor‐related human ST2 gene in UT‐7 and TM12 cells

1999 • 222 citations

Interactions of the Novel Antimicrobial Peptide Buforin 2 with Lipid Bilayers: Proline as a Translocation Promoting Factor

2000 • 208 citations

ATP is required for receptor-mediated endocytosis in intact cells.

1990 • 206 citations

Antitumor activity of magainin analogues against human lung cancer cell lines.

1992 • 157 citations

Modulation of Magainin 2−Lipid Bilayer Interactions by Peptide Charge

1997 • 156 citations

Novel Tat-Peptide Chelates for Direct Transduction of Technetium-99m and Rhenium into Human Cells for Imaging and Radiotherapy

2000 • 148 citations

Kinetics of Pore Formation by an Antimicrobial Peptide, Magainin 2, in Phospholipid Bilayers

1995 • 148 citations

Selective Cytotoxicity of Dermaseptin S3 toward IntraerythrocyticPlasmodium falciparum and the Underlying Molecular Basis

1997 • 143 citations

The antimicrobial peptides lactoferricin B and magainin 2 cross over the bacterial cytoplasmic membrane and reside in the cytoplasm

2001 • 128 citations

Antimalarial Activities of Dermaseptin S4 Derivatives

2000 • 117 citations

PR-39, a Syndecan-inducing Antimicrobial Peptide, Binds and Affects p130Cas

1998 • 108 citations

Translocation of the pAntp Peptide and Its Amphipathic Analogue AP-2AL

2001 • 105 citations

Development of Novel Antimicrobial Agents: Emerging Strategies

2002 • 99 citations

Development of Novel Antimicrobial Agents: Emerging Strategies

2003 • 99 citations

Experimental local therapy of human melanoma with lytic magainin peptides

1995 • 75 citations

Interactions between a new class of eukaryotic antimicrobial agents and isolated rat liver mitochondria

1989 • 69 citations

Affinity driven molecular transfer from erythrocyte membrane to target cells

2001 • 47 citations

Translocation of protegrin I through phospholipid membranes: role of peptide folding

2002 • 39 citations

Magainin-induced cytotoxicity in eukaryotic cells: kinetics, dose-response and channel characteristics

1995 • 30 citations

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