Bioenergetic scaling: metabolic design and body-size constraints in mammals.

The Respiratory Chain and Oxidative Phosphorylation

1956 • 2,073 citations

RESPIRATORY ENZYMES IN OXIDATIVE PHOSPHORYLATION

1955 • 1,457 citations

Scaling of respiratory variables in mammals

1967 • 840 citations

The causes and functions of mitochondrial proton leak

1994 • 472 citations

Lethal myocardial ischemic injury.

1981 • 451 citations

Mitochondrial creatine kinase: a key enzyme of aerobic energy metabolism

1992 • 439 citations

Ultrastructural quantitation of mitochondria and myofilaments in cardiac muscle from 10 different animal species including man

1992 • 394 citations

Control of oxidative metabolism and oxygen delivery in human skeletal muscle: a steady-state analysis of the work/energy cost transfer function.

1985 • 379 citations

Influence of mitochondrial content on the sensitivity of respiratory control.

1987 • 326 citations

The Evolution of Endothermy in Mammals and Birds: From Physiology to Fossils

1995 • 259 citations

Multiple controls of oxidative metabolism in living tissues as studied by phosphorus magnetic resonance.

1986 • 256 citations

Relation between phosphate metabolites and oxygen consumption of heart in vivo

1989 • 249 citations

Body mass dependence of H+ leak in mitochondria and its relevance to metabolic rate

1993 • 247 citations

Noninvasive Study of High-Energy Phosphate Metabolism in Human Heart by Depth-Resolved ³¹ P NMR Spectroscopy

1985 • 217 citations

³¹P NMR saturation transfer measurements of the steady state rates of creatine kinase and ATP synthetase in the rat brain

1982 • 203 citations

The mass exponent for energy metabolism is not a statistical artifact

1983 • 184 citations

Phosphate metabolite imaging and concentration measurements in human heart by nuclear magnetic resonance

1990 • 136 citations

Design of the mammalian respiratory system. VII. Scaling mitochondrial volume in skeletal muscle to body mass

1981 • 133 citations

Scaling of oxidative and glycolytic enzymes in mammals

1981 • 131 citations

Adjustment of K′ to Varying pH and pMg for the Creatine Kinase, Adenylate Kinase and Atp Hydrolysis Equilibria Permitting Quantitative Bioenergetic Assessment

1995 • 131 citations

Bioenergetic studies of mitochondrial oxidative phosphorylation using 31phosphorus NMR.

1985 • 124 citations

Quantitative studies of human cardiac metabolism by 31P rotating-frame NMR.

1987 • 119 citations

Evolution of mammalian endothermic metabolism: mitochondrial activity and cell composition

1989 • 110 citations

The Gibbs-Donnan near-equilibrium system of heart

1990 • 94 citations

Variations in function and design: Testing symmorphosis in the respiratory system

1992 • 86 citations

Equilibrium state of ATP-driven ion pumps in relation to physiological ion concentration gradients.

1981 • 80 citations

Scaling mitochondrial volume in heart to body mass

1984 • 76 citations

Theoretical support for the heart phosphocreatine energy transport shuttle based on the intracellular diffusion limited mobility of ADP

1985 • 67 citations

Developmental changes in the relation between phosphate metabolites and oxygen consumption in the sheep heart in vivo.

1989 • 64 citations

Imaging of human brain creatine kinase activity in vivo

1989 • 54 citations

Metabolic response of the human heart to inotropic stimulation: In vivo phosphorus‐31 studies of normal and cardiomyopathic myocardium

1992 • 47 citations

Total Cytochrome Oxidase Activity and its Relation to Basal and Maximal Metabolism

1961 • 38 citations

The creatine phosphate energy shuttle—The molecular asymmetry of a “pool”

1987 • 37 citations

Cytochrome Oxidase Activity and Body Weight in Rats and in Three Species of Large Animals

1956 • 31 citations

Bioenergetics and control of oxygen consumption in the in situ rat heart

1994 • 30 citations