Painful sensation induced by a thermal cutaneous stimulus

Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.

1969 • 1,011 citations

THE SKIN SENSES

1969 • 744 citations

Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn.

1970 • 678 citations

Myelinated afferent fibres responding specifically to noxious stimulation of the skin

1967 • 591 citations

Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses

1977 • 583 citations

Cutaneous Mechanoreceptors and Nociceptors

1973 • 561 citations

Pain Sensations and Reactions

1953 • 553 citations

Neural Events and the Psychophysical Law

1970 • 547 citations

The measurement of pain; prototype for the quantitative study of subjective responses.

1957 • 496 citations

Comparison of responses of warm and nociceptive C-fiber afferents in monkey with human judgments of thermal pain

1978 • 437 citations

Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli

1975 • 425 citations

THE RÔLE OF FIBER SIZE IN THE ESTABLISHMENT OF A NERVE BLOCK BY PRESSURE OR COCAINE

1929 • 392 citations

Morphological features of functionally defined neurons in the marginal zone and substantia gelatinosa of the spinal dorsal horn

1979 • 378 citations

STUDIES ON PAIN. A NEW METHOD FOR MEASURING PAIN THRESHOLD: OBSERVATIONS ON SPATIAL SUMMATION OF PAIN

1940 • 359 citations

Spatial and temporal transformations of input to spinothalamic tract neurons and their relation to somatic sensations

1978 • 346 citations

Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb.

1974 • 344 citations

Trigeminothalamic neurons in nucleus caudalis responsive to tactile, thermal, and nociceptive stimulation of monkey's face

1976 • 343 citations

Is There a Sensory Threshold?

1961 • 337 citations

Myelinated afferent fibres innervating the primate skin and their response to noxious stimuli

1968 • 335 citations

Nervous outflow from the cat's foot during noxious radiant heat stimulation

1974 • 330 citations

STUDIES ON PAIN. OBSERVATIONS ON PAIN DUE TO LOCAL COOLING AND ON FACTORS INVOLVED IN THE “COLD PRESSOR” EFFECT

1941 • 328 citations

Excitation of marginal and substantia gelatinosa neurons in the primate spinal cord: Indications of their place in dorsal horn functional organization

1978 • 322 citations

Relationship between pain and tissue damage due to thermal radiation

1959 • 314 citations

Afferent G Units Responding to Mechanical, Thermal and Chemical Stimuli in Human Non‐Glabrous Skin

1974 • 299 citations

Characteristics of second pain and flexion reflexes indicative of prolonged central summation

1972 • 284 citations

Primate cutaneous sensory units with unmyelinated (C) afferent fibers

1977 • 282 citations

Cutaneous mechanoreceptors with afferent C fibres

1960 • 281 citations

VARIATIONS IN CUTANEOUS AND VISCERAL PAIN SENSITIVITY IN NORMAL SUBJECTS 1

1944 • 270 citations

An analysis of response properties of spinal cord dorsal horn neurones to nonnoxious and noxious stimuli in the spinal rat

1977 • 268 citations

CORD CELLS RESPONDING TO TOUCH, DAMAGE, AND TEMPERATURE OF SKIN

1960 • 267 citations

Responses of neurons in primate ventral posterior lateral nucleus to noxious stimuli

1980 • 261 citations

Response of unmyelinated (C) polymodal nociceptors to thermal stimuli applied to monkey's face

1976 • 261 citations

Relation of Peripheral Nerve Fiber Size and Sensation in Man

1960 • 260 citations

Evoked cerebral responses to noxious thermal stimuli in humans

1976 • 250 citations

Nociceptor-driven dorsal horn neurones in the lumbar spinal cord of the cat

1976 • 242 citations

Somatic stimuli exciting spinothalamic projections to thalamic neurons in cat and monkey

1961 • 225 citations

Functional properties of primary afferent units probably related to pain mechanisms in primate glabrous skin

1976 • 210 citations

Nociceptive responses of neurons in medial thalamus and their relationship to spinothalamic pathways

1978 • 208 citations

Response characteristics of cutaneous warm receptors in the monkey

1980 • 203 citations

Neurones responding to noxious stimulation in VB complex and caudal adjacent regions in the thalamus of the rat

1980 • 197 citations

The sensitization of high threshold mechanoreceptors with myelinated axons by repeated heating.

1977 • 194 citations

Responses of primate spinothalamic neurons to graded and to repeated noxious heat stimuli

1979 • 189 citations

A comparison between the discharges of human nociceptive nerve fibres and the subject's ratings of his sensations.

1979 • 186 citations

CUTANEOUS HEAT AND COLD RECEPTORS WITH SLOWLY CONDUCTING (C) AFFERENT FIBRES

1959 • 182 citations

Analysis of cutaneous warm and cold fibres in primates

1971 • 173 citations

Signal detection theory measurement of pain: A review and critique

1977 • 172 citations

Sensitization of myelinated nociceptive afferents that innervate monkey hand

1979 • 165 citations

Laser emitted radiant heat for pain research

1975 • 156 citations

The representation of facial temperature in the caudal trigeminal nucleus of the cat.

1978 • 146 citations

Sensory-decision theory analysis of the placebo effect on the criterion for pain and thermal sensitivity (d').

1969 • 145 citations

Somatic stimuli, spinal pathways, and size of cutaneous fibers influencing unit activity in the medial medulary reticular formation

1969 • 140 citations

Warm receptors in the nasal region of cats

1969 • 140 citations

The Specificity of Afferent Cutaneous C Fibres in Mammals

1960 • 138 citations

Posterior intralaminar region in rat: Neuronal responses to noxious and nonnoxious cutaneous stimuli

1981 • 136 citations

PAIN AND TOUCH FIBERS IN PERIPHERAL NERVES

1933 • 130 citations

Responses of spinocervical tract neurones to noxious stimulation of the skin.

1977 • 129 citations

Ascending projections from marginal zone (Lamina I) neurons of the spinal dorsal horn

1975 • 128 citations

A scale of apparent intensity of electric shock.

1958 • 124 citations

Neurophysiological characterization of the anterolateral quadrant neurons subserving pain in M. Mulatta

1975 • 121 citations

Sensory decision theory methods in pain research: A reply to Rollman

1977 • 111 citations

The thermal sensitivity of the polymodal nociceptors in the monkey.

1976 • 109 citations

A Laser Stimulator for the Study of Cutaneous Thermal and Pain Sensations

1976 • 106 citations

Uniformity of the Pain Threshold in Man

1940 • 105 citations

The Influence of Skin Temperature upon the Pain Threshold as Evoked by Thermal Radiation

1951 • 104 citations

The Discharge of Specific, Cold Fibres at High Temperatures

1952 • 101 citations

Encoding of noxious heat messages in neurons of the ventrobasal thalamic complex of the rat

1980 • 101 citations

Somatosensory Responses of Bulboreticular Units in Awake Cat: Relation to Escape-Producing Stimuli

1971 • 100 citations

Single trial analysis of evoked potentials to noxious thermal stimulation in man

1980 • 99 citations

Thresholds of Pain and Reflex Contraction as Related to Noxious Stimulation

1953 • 98 citations

Response of thalamic neurons to thermal stimulation of the tongue.

1968 • 95 citations

Acupunctural Analgesia? Evaluation by Signal Detection Theory

1974 • 94 citations

ANALYSIS OF SENSATION IN TERMS OF THE NERVE IMPULSE

1934 • 93 citations

Response of trigeminal ganglion neurons to thermal stimulation of oral-facial regions. I. Steady-state response.

1970 • 93 citations

Thermally Induced Pain, the Dol Scale, and the Psychophysical Power Law

1968 • 89 citations

Peripheral fiber correlates to noxious thermal stimulation in humans

1980 • 89 citations

The relationship of experimental pain tolerance to pain threshold.

1964 • 85 citations

THE REPRESENTATION OF CUTANEOUS SENSE IN THE THALAMUS OF THE CAT AND MONKEY

1954 • 82 citations

Neuronal and behavioural responses in rats during noxious stimulation of the tail

1977 • 81 citations

Labelling of cells in the medulla oblongata and the spinal cord of the monkey after injections of horseradish peroxidase in the thalamus

1975 • 78 citations

Physiological laminar organization of the dorsal horn of M. mulatta

1974 • 77 citations

Convergence in a thermal afferent pathway in the rat.

1975 • 76 citations

Evidence for a Double Peripheral Pathway for Pain

1958 • 75 citations

The heat sensitization of polymodal nociceptors in the rabbit and its independence of the local blood flow.

1979 • 75 citations

Relationship between noxious cold stimuli and the magnitude of pain sensation in man

1983 • 74 citations

Primate cutaneous thermal nociceptors.

1971 • 73 citations

Individual differences in pain thresholds.

1956 • 73 citations

The temperature sensitivity of the Type I slowly adapting mechanoreceptors in cats and monkeys

1972 • 71 citations

Single units activities in ventral posterior and posterior group thalamic nuclei during nociceptive and non nociceptive stimulations in the cat.

1977 • 71 citations

Response of trigeminal ganglion neurons to thermal stimulation of oral-facial regions. II. Temperature change response.

1970 • 70 citations

Modifications of the firing rate of bulbar reticular units (nucleus gigantocellularis) after intra-arterial injection of bradykinin into the limbs

1973 • 70 citations

STUDIES ON PAIN: DISCRIMINATION OF DIFFERENCES IN INTENSITY OF A PAIN STIMULUS AS A BASIS OF A SCALE OF PAIN INTENSITY

1947 • 69 citations

Spinothalamic Tract Neurons in the Substantia Gelatinosa

1978 • 66 citations

A device to measure cutaneous temperature sensitivity in humans and subhuman species

1975 • 65 citations

Medial bulboreticular response to peripherally applied noxious stimuli

1974 • 62 citations

Pricking Pain Threshold in Different Body Areas.

1952 • 60 citations

Responses of small myelinated ‘warm’ fibers to noxious heat stimuli applied to the monkey's face

1973 • 59 citations

Beiträge zur Physiologie des Schmerzsinns

1894 • 59 citations

Spatial Summation of Pain

1958 • 59 citations

Noxious and tactile input to medial structures of midbrain and pons in the rat

1978 • 53 citations

Measurement of Heating of the Skin During Exposure to Infrared Radiation

1958 • 53 citations

Sensitivity of cutaneous cold fibers to noxious heat: paradoxical cold discharge

1977 • 53 citations

Suggestions for Pain Reduction and Response to Cold-Induced Pain

1974 • 51 citations

Thermal pain in humans: influence of the rate of stimulation

1978 • 51 citations

STUDIES ON PAIN: QUANTITATIVE MEASUREMENTS OF TWO PAIN SENSATIONS OF THE SKIN, WITH REFERENCE TO THE NATURE OF THE “HYPERALGESIA OF PERIPHERAL NEURITIS”

1945 • 49 citations

Spatial summation of thermal pain in human beings.

1979 • 49 citations

THE PLACEBO RESPONSE

1963 • 49 citations

Stimulus-response relations in high-threshold mechanothermal fibers innervating primate glabrous skin

1977 • 49 citations

Pain Sensations and Reactions

1953 • 45 citations

Response of cold receptors to low skin temperatures in nose of the cat

1980 • 44 citations

Discrimination of painful stimuli in human beings: influence of stimulation area.

1980 • 43 citations

Neuronal responses to noxious stimulation in rat somatosensory cortex

1982 • 42 citations

Response properties of slowly adapting mechanoreceptors to temperature stimulation in cats

1972 • 41 citations

Failure of acupuncture to produce localized analgesia

1977 • 40 citations

Adaptation of thermal pain in the skin

1962 • 38 citations

Temperature thresholds for cutaneous pain

1959 • 37 citations

THE PRODUCTION AND CHARACTERISTICS OF “SECOND PAIN”

1964 • 35 citations

Untersuchungen über die bei einer einzelnen momentanen Hautreizung auftretenden zwei stechenden Empfindungen¹

1902 • 35 citations

Determination of the Pain Threshold on Untrained Subjects

1950 • 34 citations

Variability in the Pain Threshold

1943 • 32 citations

Changes in burning pain threshold induced by acupuncture in man

1976 • 31 citations

Acupuncture, Pain, and Signal Detection Theory

1975 • 31 citations

Constancy of heat pain characteristics to changes in skin and body temperature

1977 • 29 citations

EFFECTS OF HYPOXIA AND HYPERCAPNIA ON PERCEPTION OF THERMAL CUTANEOUS PAIN

1948 • 28 citations

THE PERIPHERAL UNIT FOR PAIN

1944 • 27 citations

SOME OBSERVATIONS ON THE CENTRAL PATHWAY FOR CUTANEOUS IMPULSES IN THE CAT

1955 • 26 citations

PAIN AND SOME FACTORS THAT MODIFY IT

1951 • 24 citations

Nociception

1975 • 23 citations

Localization of specific thermoreceptors in spinal trigeminal nucleus of the cat

1979 • 21 citations

Pain measurement by the radiant heat method: individual differences in pain sensitivity, the effects of skin temperature, and stimulus duration.

1951 • 19 citations

A contact stimulator for the study of cutaneous thermal sensibility.

1974 • 16 citations

Method for the Rapid Measurement of Skin Temperature During Exposure to Intense Thermal Radiation

1953 • 16 citations

THERMAL SENSATION AND DISCRIMINATION IN RELATION TO INTENSITY OF STIMULUS

1941 • 14 citations

Relation of Skin Temperature to Pain Threshold

1955 • 14 citations

Die verschiedenen Schmerzqualitäten¹

1909 • 13 citations

Ueber die Summation von Hautreizen

1892 • 13 citations

Studies on Pain

1958 • 12 citations

Nociceptive responses of neurons in the posterior group of nuclei and medial thalamus.

1978 • 11 citations

THE STRUCTURAL IDENTITY OF THE PAIN SPOT IN HUMAN SKIN

1944 • 10 citations

Effects of noxious stimuli on primate si cortical neurons

1981 • 8 citations

Ueber die unter physiologischen Verhältnissen zu beobachtende Verlangsamung der Leitung von Schmerzempfindungen bei Anwendung von thermischen Reizen

1884 • 7 citations

Spatial Summation of Pain

1959 • 7 citations

I. La Dissociation des douleurs cutanées et la différenciation des conducteurs algiques

1929 • 7 citations

Pain and thermal burns in skin areas previously exposed to ultraviolet radiation

1960 • 6 citations

OBSERVATIONS ON ELECTRICAL STIMULATION OF PAIN FIBRES IN AN EXPOSED HUMAN SENSORY NERVE

1948 • 6 citations

The Latency of Pricking-Pain Sensation: I. The Effect of Acetophenetidin and Anacin. II. The Effect of Repeated Stimulation

1965 • 5 citations

Unit responses in the somatosensory cerebral cortex of the rat following temperature changes in scrotal skin.

1972 • 4 citations

Thalamic neurones responding to scrotal skin temperature in rats.

1972 • 3 citations

Subordination of intolerance to threshold in thermal pain

1978 • 3 citations

Pain sensibility: A variable human factor

1929 • 2 citations