Plant defense peptides

Peptide Antibiotics and Their Role in Innate Immunity

1995 • 1,602 citations

Defensins: Antimicrobial and Cytotoxic Peptides of Mammalian Cells

1993 • 986 citations

LIPID-TRANSFER PROTEINS IN PLANTS

1996 • 929 citations

Pathogen-induced systemic activation of a plant defensin gene in Arabidopsis follows a salicylic acid-independent pathway.

1996 • 927 citations

Plant Defensins: Novel Antimicrobial Peptides as Components of the Host Defense System

1995 • 749 citations

Different Temporal and Spatial Gene Expression Patterns Occur during Anther Development.

1990 • 693 citations

Small cysteine-rich antifungal proteins from radish: their role in host defense.

1995 • 653 citations

Antimicrobial Peptides from Plants

1997 • 643 citations

Structure of the hydrophobic protein crambin determined directly from the anomalous scattering of sulphur

1981 • 621 citations

Analysis of two novel classes of plant antifungal proteins from radish (Raphanus sativus L.) seeds.

1992 • 573 citations

Innate immunity of insects

1995 • 549 citations

Determination of the three-dimensional solution structure of the C-terminal domain of cellobiohydrolase I from Trichoderma reesei. A study using nuclear magnetic resonance and hybrid distance geometry-dynamical simulated annealing

1989 • 513 citations

Cell-specific expression of the carrot EP2 lipid transfer protein gene.

1991 • 500 citations

Insect immunity. Septic injury of Drosophila induces the synthesis of a potent antifungal peptide with sequence homology to plant antifungal peptides

1994 • 439 citations

Immune reactions in Drosophila and other insects: a model for innate immunity

1993 • 417 citations

Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae

1995 • 384 citations

Lipid transfer proteins (nsLTPs) from barley and maize leaves are potent inhibitors of bacterial and fungal plant pathogens

1993 • 372 citations

The defensive role of nonspecific lipid-transfer proteins in plants

1995 • 366 citations

Hevein: an antifungal protein from rubber-tree (Hevea brasiliensis) latex

1991 • 359 citations

A Potent Antimicrobial Protein from Onion Seeds Showing Sequence Homology to Plant Lipid Transfer Proteins

1995 • 351 citations

Overexpression of an endogenous thionin enhances resistance of Arabidopsis against Fusarium oxysporum.

1997 • 343 citations

Antimicrobial peptides from Amaranthus caudatus seeds with sequence homology to the cysteine/glycine-rich domain of chitin-binding proteins

1992 • 337 citations

Snakin-1, a Peptide from Potato That Is Active Against Plant Pathogens

1999 • 315 citations

Fungal Membrane Responses Induced by Plant Defensins and Thionins

1996 • 311 citations

Isolation and characterization of a novel class of plant antimicrobial peptides form Mirabilis jalapa L. seeds.

1992 • 298 citations

Wound-induced accumulation of mRNA containing a hevein sequence in laticifers of rubber tree (Hevea brasiliensis).

1990 • 271 citations

Susceptibility of Phytopathogenic Bacteria to Wheat Purothionins In Vitro

1972 • 270 citations

Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants

1988 • 270 citations

Tissue-Specific Expression of a Gene Encoding a Cell Wall-Localized Lipid Transfer Protein from Arabidopsis

1994 • 263 citations

A new family of basic cysteine‐rich plant antifungal proteins from Brassicaceae species

1993 • 255 citations

The three-dimensional structure of α1-purothionin in solution: combined use of nuclear magnetic resonance, distance geometry and restrained molecular dynamics

1986 • 250 citations

In Vitro Antifungal Activity of a Radish (Raphanus sativus L.) Seed Protein Homologous to Nonspecific Lipid Transfer Proteins

1992 • 223 citations

A non‐specific lipid transfer protein from Arabidopsis is a cell wall protein

1993 • 218 citations

High-resolution crystal structure of the non-specific lipid-transfer protein from maize seedlings

1995 • 215 citations

Molecular cloning and analysis of four potato tuber mRNAs

1988 • 212 citations

Enhanced tolerance to bacterial pathogens caused by the transgenic expression of barley lipid transfer protein LTP2

1997 • 210 citations

Solution structure of .gamma.1-H and .gamma.1-P thionins from barley and wheat endosperm determined by proton NMR: a structural motif common to toxic arthropod proteins

1993 • 207 citations

Expression of the α‐thionin gene from barley in tobacco confers enhanced resistance to bacterial pathogens

1993 • 200 citations

Purification and characterization of a novel antimicrobial peptide from maize (Zea mays L.) kernels.

1992 • 197 citations

Selective expression of a probable amylase/protease inhibitor in barley aleurone cells: Comparison to the barley amylase/subtilisin inhibitor

1986 • 184 citations

Oxford surveys of plant molecular and cell biology

1989 • 181 citations

Developmental and pathogen‐induced expression of three barley genes encoding lipid transfer proteins

1993 • 175 citations

Mutational Analysis of a Plant Defensin from Radish (Raphanus sativus L.) Reveals Two Adjacent Sites Important for Antifungal Activity

1997 • 165 citations

Two hevein homologs isolated from the seed of Pharbitis nil L. exhibit potent antifungal activity

1998 • 161 citations

Phospholipid transfer protein: full-length cDNA and amino acid sequence in maize. Amino acid sequence homologies between plant phospholipid transfer proteins.

1988 • 156 citations

The N-Terminal Cysteine-Rich Domain of Tobacco Class I Chitinase Is Essential for Chitin Binding but Not for Catalytic or Antifungal Activity

1993 • 153 citations

Three‐Dimensional Structure in Solution of a Wheat Lipid‐Transfer Protein from Multidimensional ¹H‐NMR Data

1994 • 152 citations

Thionins: Plant Peptides that Modify Membrane Permeability in Cultured Mammalian Cells

1981 • 144 citations

Spatial and temporal expression of a maize lipid transfer protein gene.

1991 • 144 citations

Genes Involved in Plant Defense

1992 • 142 citations

Plant Proteins that Confer Resistance to Pests and Pathogens

1991 • 138 citations

Plant Proteins that Confer Resistance to Pests and Pathogens

1997 • 135 citations

Purification and antipathogenic activity of lipid transfer proteins (LTPs) from the leaves of Arabidopsis and spinach

1993 • 132 citations

Pseudothionin‐St1, a potato peptide active against potato pathogens

1994 • 131 citations

Antimicrobial peptides fromMirabilis jalapa andAmaranthus caudatus: expression, processing, localization and biological activity in transgenic tobacco

1996 • 130 citations

Characterization of a New Antifungal Chitin-Binding Peptide from Sugar Beet Leaves

1997 • 129 citations

Ubiquitous Natural Antibiotics

1994 • 127 citations

Isolation of a cDNA Clone for Spinach Lipid Transfer Protein and Evidence that the Protein Is Synthesized by the Secretory Pathway

1991 • 125 citations

Rice non-specific lipid transfer protein: the 1.6 å crystal structure in the unliganded state reveals a small hydrophobic cavity

1998 • 124 citations

Barley lipid-transfer protein complexed with palmitoyl CoA: the structure reveals a hydrophobic binding site that can expand to fit both large and small lipid-like ligands

1997 • 123 citations

Hevein: NMR assignment and assessment of solution-state folding for the agglutinin-toxin motif

1993 • 121 citations

Inactivation of the sapA to sapF Locus of Erwinia chrysanthemi Reveals Common Features in Plant and Animal Bacterial Pathogenesis

1998 • 121 citations

Molecular recognition between serine proteases and new bioactive microproteins with a knotted structure

1990 • 115 citations

A novel alpha-amylase inhibitor from amaranth (Amaranthus hypocondriacus) seeds.

1994 • 115 citations

Apidaecin multipeptide precursor structure: a putative mechanism for amplification of the insect antibacterial response.

1993 • 106 citations

Co- and post-translational processing of the hevein preproprotein of latex of the rubber tree (Hevea brasiliensis)

1991 • 105 citations

TheFusarium solani-Induced Expression of a Pea Gene Family Encoding High Cysteine Content Proteins

1991 • 105 citations

Primary structure of the hydrophobic plant protein crambin

1981 • 103 citations

A flower-specific cDNA encoding a novel thionin in tobacco

1992 • 102 citations

The gene for the major cuticular wax‐associated protein and three homologous genes from broccoli (Brassica oleracea) and their expression patterns

1995 • 102 citations

Characterization and Localization of New Antifungal Cysteine-Rich Proteins fromBeta vulgaris

1995 • 100 citations

Expression pattern of a tobacco lipid transfer protein gene within the shoot apex

1992 • 96 citations

Isolation and characterization of cDNAs coding for leaf-specific thionins closely related to the endosperm-specific hordothionin of barley (Hordeum vulgare L.)

1987 • 96 citations

Solution Structure ofAce-AMP1, a Potent Antimicrobial Protein Extracted from Onion Seeds. Structural Analogies with Plant Nonspecific Lipid Transfer Proteins

1998 • 94 citations

Purification and Molecular Cloning of cDNA for an Inducible Antibacterial Protein from Larvae of the Coleopteran, Tenebrio molitor1

1994 • 93 citations

A toxic thionin from Pyrularia pubera: Purification, properties, and amino acid sequence

1985 • 90 citations

Biodiversity of apidaecin-type peptide antibiotics. Prospects of manipulating the antibacterial spectrum and combating acquired resistance

1994 • 90 citations

Nature and regulation of pistil-expressed genes in tomato

1995 • 87 citations

Intracellular Thionins of Barley

1989 • 86 citations

A crystalline polypeptide from the seed of Crambe abyssinica

1965 • 86 citations

Cloning and nucleotide sequence of a cDNA encoding the precursor of the barley toxin alpha-hordothionin

1986 • 78 citations

ESTs reveal a multigene family for plant defensins inArabidopsis thaliana

1997 • 76 citations

Mutants of Ralstonia (Pseudomonas) solanacearum sensitive to antimicrobial peptides are altered in their lipopolysaccharide structure and are avirulent in tobacco

1997 • 76 citations

Differential effects of five types of antipathogenic plant peptides on model membranes

1997 • 73 citations

Thionin genes specifically expressed in barley leaves

1987 • 71 citations

How bacteria resist killing by host-defense peptides

1994 • 69 citations

Phosphate efflux through the channels formed by colicins and phage T5 in Escherichia coli cells is responsible for the fall in cytoplasmic ATP.

1993 • 68 citations

Synthesis and processing of thionin precursors in developing endosperm from barley (Hordeum vulgare L.)

1983 • 67 citations

¹H NMR and fluorescence studies of the complexation of DMPG by wheat non‐specific lipid transfer protein. Global fold of the complex

1997 • 66 citations

The Thionins: A Protein Family That Includes Purothionins, Viscotoxins And Crambins

1990 • 66 citations

Characterization of a predominantly pistil-expressed gene encoding a ?-thionin-like protein of Petunia inflata

1994 • 65 citations

Solution of a Protein Crystal Structure with a Model Obtained from NMR Interproton Distance Restraints

1987 • 64 citations

Purothionin analogues from barley flour

1969 • 62 citations

Differential expression of a lipid transfer protein gene in cotton fiber

1995 • 61 citations

High-level expression of a viscotoxin in Arabidopsis thaliana gives enhanced resistance against Plasmodiophora brassicae.

1998 • 59 citations

Cloning and characterization of a cDNA encoding an antimicrobial chitin-binding protein from amaranth,Amaranthus caudatus

1993 • 56 citations

Mistletoe Toxins

1973 • 55 citations

Cultivar-related differences in the distribution of cell-wall-bound thionins in compatible and incompatible interactions between barley and powdery mildew

1989 • 54 citations

GENE EXPRESSION IN ALLOPLOIDS: GENETIC CONTROL OF LIPOPUROTHIONINS IN WHEAT

1976 • 52 citations

Structural Studies of Impatiens balsamina Antimicrobial Protein (Ib-AMP1)

1998 • 52 citations

Extreme divergence of a novel wheat thionin generated by a mutational burst specifically affecting the mature protein domain of the precursor

1992 • 52 citations

Characterization and Analysis of Thionin Genes

1992 • 52 citations

Refinement of purothionins reveals solute particles important for lattice formation and toxicity. Part 2: structure of β-purothionin at 1.7 Å resolution

1995 • 51 citations

Polyadenylation site heterogeneity in mRNA encoding the precursor of the barley toxin β‐hordothionin

1986 • 50 citations

Stored mRNA in cotyledons of Vigna unguiculata seeds: nucleotide sequence of cloned cDNA for a stored mRNA and induction of its synthesis by precocious germination

1990 • 50 citations

Nucleotide sequence and endosperm-specific expression of the structural gene for the toxin α-hordothionin in barley (Hordeum vulgare L.)

1988 • 48 citations

Purothionin: a seed protein with thioredoxin activity

1981 • 43 citations

Prohevein is poorly processed but shows enhanced resistance to a chitin-binding fungus in transgenic tomato plants.

1995 • 42 citations

Analysis of the toxicity of purothionins and hordothionins for plant pathogenic bacteria

1993 • 42 citations

Lipid transfer protein genes specifically expressed in barley leaves and coleoptiles

1994 • 40 citations

Organ-Specific Occurrence and Expression of the Isoforms of Nonspecific Lipid Transfer Protein in Castor Bean Seedlings, and Molecular Cloning of a Full-Length cDNA for a Cotyledon-Specific Isoform1

1991 • 39 citations

Comparison of solution and crystal structures of maize nonspecific lipid transfer protein: A model for a potential in vivo lipid carrier protein

1998 • 39 citations

A new α-helical motif in membrane active peptides

1991 • 39 citations

The effect of light on the biosynthesis of leaf‐specific thionins in barley, Hordeum vulgare

1989 • 38 citations

¹H‐nmr studies on the structure of a new thionin from barley endosperm

1995 • 37 citations

Refinement of purothionins reveals solute particles important for lattice formation and toxicity. Part 1: α₁-purothionin revisited

1995 • 36 citations

Cloning and characterization of a cotton lipid transfer protein gene specifically expressed in fiber cells

1997 • 36 citations

Processing of Thionin Precursors in Barley Leaves by a Vacuolar Proteinase

1997 • 35 citations

Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L.

1995 • 34 citations

Organ-specific expression of highly divergent thionin variants that are distinct from the seed-specific crambin in the crucifer Crambe abyssinica

1994 • 32 citations

Effects of thionins on β‐glucuronidase in vitro and in plant protoplasts

1992 • 30 citations

The effect of chemical stress on the polypeptide composition of the intercellular fluid of barley leaves

1989 • 30 citations

Purothionins inAegilops-Triticum spp.

1969 • 29 citations

Antifungal activity of synthetic 15-mer peptides based on the Rs-AFP2 (Raphanus sativus antifungal protein 2) sequence.

1996 • 23 citations

cDNA-derived identification of novel thionin precursors in Viscum album that contain highly divergent thionin domains but conserved signal and acidic polypeptide domains

1993 • 23 citations

Homoeologous chromosomal location of the genes encoding thionins in wheat and rye

1979 • 23 citations

Selective disulphide linkage of plant thionins with other proteins

1995 • 22 citations

¹H NMR characterization of two crambin species

1987 • 22 citations

Interactions of Thionin from Pyrularia pubera with Dipalmitoylphosphatidylglycerol Large Unilamellar Vesicles

1997 • 21 citations

Subcellular localization of type I thionins in the endosperms of wheat and barley

1993 • 21 citations

Epidermis-Specific Transcripts (Nucleotide Sequence of a Full-Length cDNA of EPI12, Encoding a Putative Lipid Transfer Protein)

1993 • 16 citations

High Conservation among Sequences Encoding Type-V Thionins in Wheat and Aegilops

1995 • 13 citations

Engineering plants against pathogens: A general strategy

1996 • 10 citations