The radiation-induced bystander effect: evidence and significance

Induction of sister chromatid exchanges by extremely low doses of alpha-particles.

1992 • 979 citations

Transmission of chromosomal instability after plutonium α-particle irradiation

1992 • 603 citations

Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells

1997 • 592 citations

Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells

2001 • 586 citations

Non-targeted and Delayed Effects of Exposure to Ionizing Radiation: II. Radiation-Induced Genomic Instability and Bystander EffectsIn Vivo,Clastogenic Factors and Transgenerational Effects

2003 • 535 citations

Radiation-Induced Bystander Effects: Past History and Future Directions

2001 • 496 citations

Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells.

1997 • 445 citations

Studies of bystander effects in human fibroblasts using a charged particle microbeam

1998 • 410 citations

Factors underlying the cell growth-related bystander responses to alpha particles.

2000 • 346 citations

Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alpha-particle-irradiated normal human fibroblast cultures.

2002 • 325 citations

The Bystander Effect in Radiation Oncogenesis: I. Transformation in C3H 10T½ CellsIn Vitrocan be Initiated in the Unirradiated Neighbors of Irradiated Cells

2001 • 308 citations

Alpha-Particle-Induced Sister Chromatid Exchange in Normal Human Lung Fibroblasts: Evidence for an Extranuclear Target

1996 • 286 citations

Unexpected Sensitivity to the Induction of Mutations by Very Low Doses of Alpha-Particle Radiation: Evidence for a Bystander Effect

1999 • 265 citations

Radiation abscopal antitumor effect is mediated through p53.

2003 • 243 citations

Induction of Radioresistance by a Nitric Oxide-Mediated Bystander Effect

2001 • 232 citations

Chromosomal instability in unirradiated cells induced in vivo by a bystander effect of ionizing radiation.

2000 • 211 citations

Bystander effect produced by radiolabeled tumor cells in vivo

2002 • 193 citations

Partial volume rat lung irradiation: An evaluation of early DNA damage

1998 • 164 citations

Alpha-particle-induced p53 protein expression in a rat lung epithelial cell strain.

1994 • 161 citations

Adaptive Response and the Bystander Effect Induced by Radiation in C3H 10T½ Cells in Culture

2001 • 146 citations

Stress-induced secretion of growth inhibitors: a novel tumor suppressor function of p53

1998 • 142 citations

Alpha-Particle-Induced Increases in the Radioresistance of Normal Human Bystander Cells

2002 • 132 citations

Bystander Effects: Intercellular Transmission of Radiation Damage Signals

2002 • 130 citations

Evidence for Pronounced Bystander Effects Caused by Nonuniform Distributions of Radioactivity using a Novel Three-Dimensional Tissue Culture Model

1999 • 126 citations

Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect.

2003 • 119 citations

Bystander and Delayed Effects after Fractionated Radiation Exposure

2002 • 118 citations

High and low fluences of alpha-particles induce a G1 checkpoint in human diploid fibroblasts.

2000 • 102 citations

Effect of 239 PuO 2 Particle Number and Size on the Frequency and Distribution of Chromosome Aberrations in the Liver of the Chinese Hamster

1974 • 58 citations

Bystander effects caused by nonuniform distributions of DNA-incorporated 125I

2002 • 47 citations

Flow cytometry as a strategy to study radiation‐induced bystander effects in co‐culture systems

2003 • 36 citations