Involvement of matrix metalloproteinase-2 activity in invasion and metastasis of pancreatic carcinoma

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

1980 • 1,991 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion and metastasis

1993 • 606 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Metalloproteinases and cancer invasion.

1990 • 399 citations

Stromal expression of 72 kda type IV collagenase (MMP-2) and TIMP-2 mRNAs in colorectal neoplasia.

1992 • 333 citations

Association Between Expression of Activated 72-Kilodalton Gelatinase and Tumor Spread in Non-Small-Cell Lung Carcinoma

1993 • 278 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Expression and in‐situ localization of genes coding for extracellular matrix proteins and extracellular matrix degrading proteases in pancreatic cancer

1995 • 234 citations

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1996 • 232 citations

Interstitial Collagenase Is Required for Angiogenesis in Vitro

1994 • 231 citations

Expression of genes encoding type IV collagen-degrading metalloproteinases and tissue inhibitors of metalloproteinases in various human tumor cells.

1992 • 228 citations

Inhibition of the metastatic spread and growth of B16‐BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor

1994 • 218 citations

Association of MMP-2 Activation Potential With Metastatic Progression in Human Breast Cancer Cell Lines Independent of MMP-2 Production

1993 • 216 citations

Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94).

1996 • 195 citations

Inhibition of organ invasion by the matrix metalloproteinase inhibitor batimastat (BB-94) in two human colon carcinoma metastasis models.

1995 • 184 citations

A one-step sandwich enzyme immunoassay for human matrix metalloproteinase 2 (72-kDa gelatinase/type IV collagenase) using monoclonal antibodies

1993 • 172 citations

High level of MT-MMP expression is associated with invasiveness of cervical cancer cells

1996 • 165 citations

A one-step sandwich enzyme immunoassay for tissue inhibitor of metalloproteinases-2 using monoclonal antibodies

1993 • 115 citations

Characterization of extracellular matrix-degrading proteinase and its inhibitor in gynecologic cancer tissues with clinically different metastatic form

1995 • 49 citations

Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: Not an invariant correlation with metastasis

1992 • 46 citations

Occurrence of an active form of gelatinase in human gastric and colorectal carcinoma tissues

1991 • 46 citations

Expression of Bcl-2 and PCNA in Duct Cells After Pancreatic Duct Ligation in Rats

1997 • 30 citations

Different pattern of zymography between human gynecologic normal and malignant tissues

1994 • 25 citations