The hr-t gene of polyoma virus

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Autocrine Secretion and Malignant Transformation of Cells

1980 • 1,370 citations

Agar suspension culture for the selective assay of cells transformed by polyoma virus

1964 • 1,265 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

Insulin Stimulates the Phosphorylation of the 95,000-Dalton Subunit of Its Own Receptor

1982 • 1,138 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

The Genome of Simian Virus 40

1978 • 948 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein

1978 • 673 citations

Plaque production by the polyoma virus

1959 • 649 citations

An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates

1979 • 540 citations

Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine

1980 • 539 citations

Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.

1979 • 530 citations

Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein

1981 • 435 citations

RNA-Directed DNA Synthesis and RNA Tumor Viruses

1972 • 420 citations

The genome of human papovavirus BKV

1979 • 378 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

Construction and analysis of viable deletion mutants of simian virus 40

1976 • 355 citations

Host-range mutants of adenovirus type 5 defective for growth in HeLa cells

1977 • 330 citations

Quantitation of simian virus 40 sequences in African green monkey, mouse and virus-transformed cell genomes

1971 • 292 citations

Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA

1979 • 292 citations

Complementation and transformation by temperature-sensitive mutants of polyoma virus

1969 • 212 citations

Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus

1977 • 211 citations

Characterization of t antigens in polyoma-infected and transformed cells

1978 • 208 citations

BK Virus DNA: Complete Nucleotide Sequence of a Human Tumor Virus

1979 • 204 citations

Transplantation of Polyoma Virus-induced Tumors in Mice

1961 • 199 citations

Phosphorylation of polyoma T antigens

1979 • 186 citations

Studies on transformation of hamster cells by polyoma virus in vitro

1961 • 178 citations

Polyoma gene function required for viral DNA synthesis

1973 • 175 citations

Protein kinase activity associated with polyoma virus middle T antigen in vitro

1979 • 174 citations

Virus-specific RNA in cells productively infected or transformed by polyoma virus

1966 • 171 citations

The nucleotide sequence and genome organization of the polyoma early region: Extensive nucleotide and amino acid homology with SV40

1979 • 162 citations

Abortive Transformation by Polyoma Virus

1968 • 156 citations

Studies on cells rendered neoplastic by polyoma virus: the problem of the presence of virus-related materials

1962 • 152 citations

Temperature-sensitive mutants of polyoma virus

1969 • 148 citations

Tumor antigens induced by nontransforming mutants of polyoma virus

1978 • 141 citations

Comparison of phosphorylation of two polyoma virus middle T antigens in vivo and in vitro

1981 • 138 citations

Hormonally induced cell shape changes in cultured rat ovarian granulosa cells.

1979 • 137 citations

Specific complement-fixing antigens in polyoma tumors and transformed cells

1965 • 123 citations

New classes of viable deletion mutants in the early region of polyoma virus

1979 • 116 citations

Comparisons of two early gene functions essential for transformation in polyoma virus and SV-40

1979 • 115 citations

Isolation of temperature-sensitive mutants of polyoma virus

1965 • 107 citations

α-amanitin-resistant D. melanogaster with an altered RNA polymerase II

1979 • 106 citations

Construction of the genetic map of the polyoma genome

1976 • 99 citations

Cellular alterations dependent upon the polyoma virus hr-t function: Separation of mitogenic from transforming capacities

1978 • 93 citations

The high affinity binding site on polyoma virus DNA for the viral large-T protein

1981 • 91 citations

Hr-t and ts-a: Two early gene functions of polyoma virus

1977 • 91 citations

Host range selection of transformation-defective hr-t mutants of polyoma virus

1977 • 91 citations

Transformation by Polyoma Virus and Simian Virus 40

1981 • 89 citations

Inactivation, by UV-, X-, and γ-radiations, of the infecting and transforming capacities of polyoma virus

1967 • 85 citations

Three species of polyoma virus tumor antigens share common peptides probably near the amino termini of the proteins

1978 • 84 citations

Construction and analysis of viable deletion mutants of polyoma virus

1979 • 80 citations

Nucleotide sequence of the DNA replication origin for human papovavirus BKV: sequence and structural homology with SV40

1978 • 78 citations

Antigenic and Immunogenic Characteristics of Nuclear and Membrane-Associated Simian Virus 40 Tumor Antigen

1980 • 77 citations

Analysis of host range of nontransforming polyoma virus mutants

1975 • 77 citations

The Polyoma virus 100K large T-antigen is not required for the maintenance of transformation

1980 • 73 citations

Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformation

1982 • 73 citations

Polyoma virus middle T antigen: relationship to cell membranes and apparent lack of ATP-binding activity.

1982 • 73 citations

Complementation between temperature-sensitive (ts) and host range nontransforming (hr-t) mutants of polyoma virus

1977 • 71 citations

Untransformed rat cells containing free and integrated dna of a polyoma nontransforming (Hr-t) mutant

1979 • 69 citations

Identification of DNA sequence changes leading to loss of transforming ability in polyoma virus.

1980 • 68 citations

Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences

1978 • 68 citations

Human chorionic gonadotropin. Amino acid sequence of the hormone-specific COOH-terminal region.

1977 • 65 citations

Relationship of polyoma virus and tumor in vivo

1960 • 61 citations

Immunoprecipitation of protein kinase activity from adenovirus 5-infected cells using antiserum directed against tumour antigens

1979 • 60 citations

Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation

1981 • 57 citations

DNA sequence alterations in Hr-t deletion mutants of polyoma virus

1979 • 56 citations

Morphogenetic genes C and Nu3 overlap in bacteriophage λ

1980 • 54 citations

Abortive Transformation by the Tsa Mutant of Polyoma Virus

1969 • 54 citations

Viable deletion mutant in the medium and large T-antigen-coding sequences of the polyoma virus genome

1980 • 53 citations

Transformation By Polyoma Virus And Simian Virus 40

1973 • 45 citations

SV40-transformed cells express SV40 T antigen-related antigens on the cell surface

1981 • 44 citations

Characterization of gonadotropin binding sites in the intracellular organelles of bovine corpora lutea and comparison with plasma membrane sites.

1981 • 44 citations

Sequences from the genome of a non-transforming mutant of polyoma virus

1978 • 42 citations

Two polyoma virus gene functions involved in the expression of the transformed phenotype in FR 3T3 rat cells I. Localization of a transformation maintenance function in the proximal half of the large T coding region

1981 • 40 citations

Requirement for the C-terminal region of middle T-antigen in cellular transformation by virus

1981 • 36 citations

Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters

1981 • 34 citations

Perspectives on genes and the molecular biology of cancer

1983 • 31 citations

25th annual symposium of fundamental cancer research

1971 • 29 citations

Transformation of rat fibroblast cells with early mutants of polyoma (tsa) and simian virus 40 (tsA30): occurrence of either A or N transformants depends on the multiplicity of infection

1980 • 27 citations

Growth and Persistence of Polyoma Early Region Deletion Mutants in Mice

1981 • 25 citations

Specific thymus-derived (T) cell recognition of papova virus-transformed cells.

1982 • 21 citations

Regions of the polyoma genome coding for T antigens

1979 • 20 citations

Polyoma T (tumor) antigen species in abortively and stably transformed cells

1979 • 16 citations

Cellular and C-type viral factors in infections by polyoma virus hr-t mutants

1979 • 15 citations

Two polyoma virus gene functions involved in the expression of the transformed phenotype in FR 3T3 rat cells II. The presence of the 56K middle-T protein in the cell membrane is not sufficient for maintenance

1981 • 10 citations

Transfer of conversion gene(s) between different Salmonella phages g341 and ϵ15

1969 • 10 citations

Absence of homology between polyoma or SV40 viral DNA and mitochondrial DNA from virus-induced tumors

1968 • 10 citations

Tumor viruses and cellular gene expression.

1976 • 8 citations

Host Cell-Modified T-Antigen in Membranes of Simian Virus 40-Transformed Hamster Cells<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 7 citations

Isolation of transformation-defective host-range mutants of polyoma virus on normal mouse cells

1982 • 7 citations