Analogs of Tetrahydrofolic Acid XV

Direct Evidence for the Presence of Histidine in the Active Center of Chymotrypsin^*

1963 • 649 citations

Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

1961 • 389 citations

LACTIC DEHYDROGENASE

1958 • 187 citations

Interaction of Aromatic Compounds With α-Chymotrypsin^*

1963 • 110 citations

Potential Anticancer Agents --L. Non-Classical Antimetabolites--II. Some Factors in the Design of Exo-Alkylating Enzyme Inhibitors, partcularly of Lactic Dehydrogenase

1960 • 63 citations

The Mechanism of Binding of Folate Analogues by Folate Reductase

1963 • 60 citations

Analogs of Tetrahydrofolic Acid. X.^1,2 Synthetic and Enzymic Studies on the Contribution of the p-Aminobenzoyl-L-glutamate Moiety of Pyrimidyl Analogs to Binding to Some Folic Cofactor Area Enzymes

1964 • 59 citations

The Cleavage of Sulfonamides¹

1953 • 56 citations

Analogs of tetrahydrofolic acid. XII. On the relative contribution by the 2‐amino and 4‐hydroxy groups of 2‐amino‐5‐(3‐anilinopropyl)‐6‐methyl‐4‐pyrimidinol to inhibition of folic reductase and thymidylate synthetase

1964 • 52 citations

Potential Anticancer Agents.¹ XLII. Tetrahydroquinazoline Analogs of Tetrahydrofolic Acid. III. An Improved Synthesis of 5,8-Dideaza-5,6,7,8-tetrahydrofolic Acid

1961 • 30 citations

Analogs of tetrahydrofolic acid. XIII. On the mode of binding of the anilino group of 2‐amino‐5‐(3‐anilinopropyl)‐6‐methyl‐4‐pyrimidinol to dihydrofolic reductase and thymidylate synthetase

1964 • 26 citations

Analogs of Tetrahydrofolic Acid. VIII.^1,2 Synthesis of N-[1-(2-Amino-4-mercapto-6-methyl-5-pyrimidyl)-3-propyl]-p- aminobenzoyl-L-glutamic Acid, a Mercapto Analog

1963 • 25 citations

Relationship between Basicity of Certain Folate Analogues and Their Affinities for Folate Reductase

1963 • 22 citations

212. Some 2 : 6-diamino- and 2-amino-6-hydroxy-derivatives of 5-aryl-4 : 5-dihydropyrimidines. A new synthesis of 4-alkyl-5-arylpyrimidines

1956 • 21 citations

Some New Syntheses of Amino- and Alkylaminopyrimidines and -pteridines

1963 • 20 citations

Potential Anticancer Agents.¹ XVIII. Synthesis of Substituted 4,5-Trimethylenepyrimidines

1959 • 19 citations

Potential Anticancer Agents.¹ LXIX. Tetrahydroquinazoline Analogs of Tetrahydrofolic Acid. IV. The Synthesis of 5,8-Dideaza-5,6,7,8-tetrahydroaminopterin

1962 • 16 citations

515. The preparation and reactions of 4-amino-2-(carboxy-methylthio)pyrimidines

1949 • 4 citations