Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

FLUORESCENCE OF CATECHOL AMINES AND RELATED COMPOUNDS CONDENSED WITH FORMALDEHYDE

1962 • 2,684 citations

CLONAL GROWTH OF MAMMALIAN CELLS IN VITRO

1956 • 1,130 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Dopamine Systems

1978 • 920 citations

The Nerve Growth Factor: Biochemistry, Synthesis, and Mechanism of Action

1980 • 733 citations

Neurotransmitter Synthesis by Neuroblastoma Clones

1972 • 695 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. II. Late ontogeny

1981 • 497 citations

A system of nomenclature for band patterns of mouse chromosomes

1973 • 368 citations

A genetic analysis of extinction: Trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells

1984 • 365 citations

Light‐microscopic immunocytochemical localization of tyrosine hydroxylase in prenatal rat brain. I. Early ontogeny

1981 • 349 citations

MPTP

1986 • 293 citations

MPTP Toxicity: Implications for Research in Parkinson's Disease

1988 • 287 citations

New Neuronal Growth Factors

1984 • 269 citations

[18] PC12 pheochromocytoma cells: culture, nerve growth factor treatment, and experimental exploitation

1987 • 243 citations

MPTP: current concepts and controversies.

1986 • 234 citations

THE DEVELOPMENT OF SOME EXTERNAL FEATURES IN MOUSE EMBRYOS

1943 • 231 citations

Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—2. Action potential generating mechanisms and morphological correlates

1983 • 227 citations

Neuronal traits of clonal cell lines derived by fusion of dorsal root ganglia neurons with neuroblastoma cells.

1985 • 203 citations

MPTP

1986 • 193 citations

Developments in neuronal cell culture

1988 • 193 citations

The effects of alpha-methyl-DOPA and alpha-methyl-metatyrosine on the metabolism of norepinephrine and serotonin in vivo.

1961 • 193 citations

Electrical membrane properties of rat substantia nigra compacta neurons in an in vitro slice preparation

1986 • 187 citations

Reconstruction of brain tissue from cell suspensions

1972 • 180 citations

Membrane patches and whole‐cell membranes: a comparison of electrical properties in rat clonal pituitary (GH3) cells.

1984 • 179 citations

Patch clamp characterization of sodium channels expressed from rat brain cDNA

1987 • 178 citations

Immortalization of Neural Cells Via Retrovirus-Mediated Oncogene Transduction

1989 • 151 citations

Target neuron-specific process formation by embryonic mesencephalic dopamine neurons in vitro.

1981 • 135 citations

Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice

1990 • 128 citations

Monoclonal antibodies recognize individual neurofilament triplet proteins.

1982 • 121 citations

DOPA decar☐ylase in the developing rat brain

1972 • 114 citations

Conservation of autosomal gene synteny groups in mouse and man

1978 • 114 citations

Immunofluorescence analysis of the time-course of extinction, reexpression, and activation of albumin production in rat hepatoma-mouse fibroblast heterokaryons and hybrids.

1981 • 114 citations

Development and characterization of clonal cell lines derived from septal cholinergic neurons

1990 • 110 citations

REGIONAL DEVELOPMENT OF CATECHOLAMINE BIBSYNTHESIS IN RAT BRAIN¹

1972 • 107 citations

Neuronal Properties of Clonal Hybrid Cell Lines Derived from Central Cholinergic Neurons

1986 • 105 citations

Immortalized young adult neurons from the septal region: generation and characterization

1990 • 78 citations

A comparison of eight different chromogen protocols for the demonstration of immunoreactive neurofilaments or glial filaments in rat cerebellum using the peroxidase-antiperoxidase method and monoclonal antibodies.

1983 • 77 citations

Different forms of tyrosine hydroxylase in central dopaminergic and noradrenergic neurons and sympathetic ganglia

1975 • 73 citations

Analysis of the 5’Region of the Human Tyrosine Hydroxylase Gene: Combinatorial Patterns of Exon Splicing Generate Multiple Regulated Tyrosine Hydroxylase Isoforms

1988 • 72 citations

Enhanced dopamine cell survival in reaggregates containing telencephalic target cells

1983 • 72 citations

Neural Transplantation: A Call for Patience Rather Than Patients

1988 • 71 citations

Neuronal properties of hybrid neuroblastoma X sympathetic ganglion cells.

1975 • 63 citations

Neuroblastoma cells in neural transplants: a neuroanatomical and behavioral analysis

1987 • 60 citations

Immunocytochemical study of PC12 cells grafted to the brain of immature rats

1985 • 57 citations

Kinetic properties of tyrosine hydroxylase purified from bovine adrenal medulla and bovine caudate nucleus

1982 • 56 citations

Application of a novel cation-exchange reagent, Igepon T-77 (N-methyl oleoyl taurate), to microbore separations of alumina extracts of catecholamines from cerebrospinal fluid, plasma, urine and brain tissue with amperometric detection

1987 • 50 citations

Evidence for the Existence of Homologous Gene Coding Regions for the Catecholamine Biosynthetic Enzymes

1983 • 49 citations

Selection for Neuroblastoma Cells that Synthesize Certain Transmitters

1974 • 45 citations

The biochemical and morphological development of differentiating dopamine neurons co-aggregated with their target cells of the corpus striatum in vitro

1982 • 40 citations

Neurotrophic effects of hippocampal target cells on developing septal cholinergic neurons in culture

1987 • 33 citations

Release of dopamine from coaggregate cultures of mesencephalic tegmentum and corpus striatum

1983 • 30 citations

A fluorometric determination of N-methyl-4-phenylpyridinium ion, using high-performance liquid chromatography

1987 • 29 citations

Effect of N‐Methyl‐4‐Phenylpyridinium Ion on Monoamine Oxidase in a Clonal Rat Pheochromocytoma Cell Line, PC 12h

1987 • 21 citations

Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP‐32‐containing cells in three‐dimensional reaggregate tissue culture

1989 • 20 citations

Quantitation of neurochemically identified neurons in reaggregate tissue cultures

1988 • 12 citations

Biochemical and morphological studies on GABA neurons in reaggregate culture

1987 • 5 citations