Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1990 • 1,955 citations

Autoimmunity to two forms of glutamate decarboxylase in insulin-dependent diabetes mellitus.

1992 • 494 citations

Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.

1992 • 487 citations

Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons

1988 • 455 citations

Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase

1988 • 334 citations

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes.

1987 • 319 citations

Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10.

1991 • 281 citations

Response of peripheral-blood mononuclear cells to glutamate decarboxylase in insulin-dependent diabetes

1992 • 275 citations

γ‐Aminobutyric Acid Outside the Mammalian Brain

1990 • 256 citations

NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse

1991 • 254 citations

The diabetic syndrome of the ?BB? Wistar rat: Possible relevance to Type 1 (insulin-dependent) diabetes in man

1982 • 249 citations

Structural and Functional Considerations of GABA in Islets of Langerhans: β-Cells and Nerves

1991 • 157 citations

Autoantibodies to a 64-Kilodalton Islet Cell Protein Precede the Onset of Spontaneous Diabetes in the BB Rat

1984 • 147 citations

The localization of laminin mRNA and protein in the postimplantation embryo and placenta of the mouse: anin situhybridization and immunocytochemical study

1988 • 141 citations

Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble.

1991 • 118 citations

Glucose regulation of the autoantigen GAD65 in human pancreatic islets.

1992 • 100 citations

High-Glucose Stimulation of 64,000-Mr Islet Cell Autoantigen Expression

1989 • 98 citations

Islet cell antigens in insulin-dependent diabetes: Pandora's box revisited

1992 • 97 citations

Recombinant Glutamic Acid Decarboxylase (Representing the Single Isoform Expressed in Human Islets) Detects IDDM-Associated 64,000-Mr Autoantibodies

1992 • 95 citations

Molecular Identification of the 62 kd Form of Glutamic Acid Decarboxylase from the Mouse

1990 • 88 citations

Autoantibodies in Nonobese Diabetic Mice Immunoprecipitate 64,000-Mr Islet Antigen

1988 • 86 citations

Glutamate Decarboxylases in Nonneural Cells of Rat Testis and Oviduct: Differential Expression of GAD₆₅ and GAD₆₇

1992 • 85 citations

Expression of Preprotachykinin-A and Neuropeptide-Y Messenger RNA in the Thymus

1990 • 76 citations

Binding of antibodies in sera from Type 1 (insulin-dependent) diabetic patients to glutamate decarboxylase from rat tissues. Evidence for antigenic and non-antigenic forms of the enzyme

1992 • 52 citations

Localization of GAD-like immunoreactivity in the pancreas and stomach of the rat and mouse

1991 • 52 citations

Molecular cloning and amino acid sequence of brain L-glutamate decarboxylase.

1990 • 49 citations

An ELISA for Antibodies to Recombinant Glutamic Acid Decarboxylase in IDDM

1992 • 40 citations

Cloning and partial nucleotide sequence of human glutamic acid decarboxylase cDNA from brain and pancreatic islets

1991 • 31 citations

Cellular and subcellular immunolocalization of L-glutamate decarboxylase in rat pancreatic islets.

1988 • 27 citations

Glutamic acid decarboxylase in insulin‐dependent diabetes mellitus

1992 • 25 citations

Ultrastructural immunocytochemical localization of l-glutamate decarboxylase and GABA in rat pancreatic zymogen granules

1988 • 13 citations

Molecular Cloning of Full-Length Glutamic Acid Decarboxylase 67 from Human Pancreas and Islets

1993 • 10 citations