Inhibition of Intimal Thickening After Balloon Angioplasty in Porcine Coronary Arteries by Targeting Regulators of the Cell Cycle

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1993 • 3,680 citations

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Antisense Oligonucleotides as Therapeutic Agents—Is the Bullet Really Magical?

1993 • 1,306 citations

Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation

1989 • 990 citations

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.

1995 • 959 citations

lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin

1994 • 903 citations

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

1992 • 749 citations

Rapamycin-FKBP Inhibits Cell Cycle Regulators of Proliferation in Vascular Smooth Muscle Cells

1995 • 592 citations

Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia.

1995 • 549 citations

Does the new angiotensin converting enzyme inhibitor cilazapril prevent restenosis after percutaneous transluminal coronary angioplasty? Results of the MERCATOR study: a multicenter, randomized, double-blind placebo-controlled trial. Multicenter European Research Trial with Cilazapril after Angioplasty to Prevent Transluminal Coronary Obstruction and Restenosis (MERCATOR) Study Group.

1992 • 548 citations

Rapamycin inhibits vascular smooth muscle cell migration.

1996 • 504 citations

Cytostatic Gene Therapy for Vascular Proliferative Disorders with a Constitutively Active form of the Retinoblastoma Gene Product

1995 • 455 citations

Percutaneous Transluminal Coronary Angioplasty

1994 • 450 citations

Gene Therapy for Vascular Smooth Muscle Cell Proliferation After Arterial Injury

1994 • 443 citations

Restenosis after balloon angioplasty. A practical proliferative model in porcine coronary arteries.

1990 • 415 citations

A Signaling Pathway to Translational Control

1996 • 370 citations

Coumadin and aspirin in prevention of recurrence after transluminal coronary angioplasty: a randomized study.

1984 • 363 citations

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty.

1995 • 363 citations

Effect of 18- to 24-hour heparin administration for prevention of restenosis after uncomplicated coronary angioplasty

1989 • 315 citations

Intimal hyperplasia after vascular injury is inhibited by antisense cdk 2 kinase oligonucleotides.

1994 • 290 citations

Experimental models of coronary artery restenosis

1992 • 216 citations

Rapamycin Resistance Tied to Defective Regulation of p27^Kip1

1996 • 213 citations

RAPAMYCIN INHIBITS ARTERIAL INTIMAL THICKENING CAUSED BY BOTH ALLOIMMUNE AND MECHANICAL INJURY

1993 • 204 citations

Downregulation of cyclin-dependent kinase 2 activity and cyclin A promoter activity in vascular smooth muscle cells by p27(KIP1), an inhibitor of neointima formation in the rat carotid artery.

1997 • 192 citations

In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene.

1994 • 184 citations

Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells.

1993 • 138 citations

Effects of cyclosporin, FK506, and rapamycin on graft-vessel disease

1991 • 133 citations

Effects of Antisense c- myb Oligonucleotides on Vascular Smooth Muscle Cell Proliferation and Response to Vessel Wall Injury

1995 • 133 citations

Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line.

1993 • 105 citations

The Three Processes Leading to Post PTCA Restenosis: Dependence on the Lesion Substrate

1995 • 101 citations

Prolonged Thrombin Inhibition Reduces Restenosis After Balloon Angioplasty in Porcine Coronary Arteries

1998 • 95 citations

Colchicine and antineoplastic therapy for the prevention of restenosis after percutaneous coronary interventions

1991 • 71 citations

Adenovirus-Mediated Transfer of the Herpes Simplex Virus Thymidine Kinase Gene Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation Following Balloon Angioplasty of the Rat Carotid Artery

1995 • 71 citations

Molecular biology: Insight into the causes and prevention of restenosis after arterial intervention

1993 • 53 citations

The Porcine Model for the Understanding of Thrombogenesis and Atherogenesis

1991 • 49 citations

Tissue-specific expression of calcium channels

1993 • 39 citations

RAPAMYCIN

1993 • 29 citations

Molecular biology of intimal proliferation

1993 • 20 citations

Molecular atherectomy for restenosis

1993 • 10 citations