Ethical and Scientific Implications of the Globalization of Clinical Research

The price of innovation: new estimates of drug development costs

2003 • 4,276 citations

International Prevalence, Recognition, and Treatment of Cardiovascular Risk Factors in Outpatients With Atherothrombosis

2006 • 1,567 citations

The Global Burden of Asthma

2006 • 1,153 citations

Coronary Intervention for Persistent Occlusion after Myocardial Infarction

2006 • 729 citations

Trends in the globalization of clinical trials

2007 • 349 citations

Pharmacogenetics goes genomic

2003 • 318 citations

Rebuilding the R&D engine in big pharma.

2008 • 232 citations

Ethical Issues in the Design and Conduct of Clinical Trials in Developing Countries

2001 • 209 citations

Ethical review of health research: a perspective from developing country researchers

2004 • 203 citations

Design of the Future REvascularization Evaluation in patients with Diabetes mellitus: Optimal management of Multivessel disease (FREEDOM) Trial

2008 • 194 citations

A National Survey of Provisions in Clinical-Trial Agreements between Medical Schools and Industry Sponsors

2002 • 184 citations

A New Colonialism? — Conducting Clinical Trials in India

2005 • 182 citations

Sensible approaches for reducing clinical trial costs

2008 • 171 citations

Specific barriers to the conduct of randomized trials

2008 • 163 citations

Invisible Barriers to Clinical Trials: The Impact of Structural, Infrastructural, and Procedural Barriers to Opening Oncology Clinical Trials

2006 • 161 citations

Human rights and maternal-fetal HIV transmission prevention trials in Africa.

1998 • 139 citations

Commercializing Clinical Trials — Risks and Benefits of the CRO Boom

2007 • 126 citations

Structural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase

2007 • 105 citations

Alcohol and Cancer

2001 • 95 citations

Processes to Activate Phase III Clinical Trials in a Cooperative Oncology Group: The Case of Cancer and Leukemia Group B

2006 • 75 citations

Ethical Oversight of Public Health Research: Can Rules and IRBs Make a Difference in Developing Countries?

2002 • 71 citations

An assessment of the quality of randomised controlled trials conducted in China

2008 • 70 citations

Informed consent in Ghana: what do participants really understand?

2007 • 69 citations

Sensible guidelines for the conduct of large randomized trials

2008 • 56 citations

Broadening the Debate

2003 • 54 citations

Ethics of clinical research in the developing world

2002 • 39 citations

The Experience with Voluntary Genomic Data Submissions at the FDA and a Vision for the Future of the Voluntary Data Submission Program

2007 • 38 citations

Clinical Trials Seen Shifting Overseas

2004 • 34 citations

Globalization of cardiovascular clinical research: The balance between meeting medical needs and maintaining scientific standards

2007 • 32 citations

Indian regulations fail to monitor growing stem-cell use in clinics

2005 • 29 citations

Medical research in India

2006 • 20 citations

Ethics of medical research in developing countries: the role of international codes of conduct

2000 • 17 citations

Drug companies cut costs with foreign clinical trials.

2005 • 14 citations

Industry-sponsored research in developing countries

2007 • 7 citations

From bench to bedside and back?

2001 • 3 citations

Deleted Work

1955 • 0 citations