Clostridium histolyticum collagenase: development of new thio ester, fluorogenic, and depsipeptide substrates and new inhibitors

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

A modified ninhydrin colorimetric analysis for amino acids

1957 • 2,207 citations

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1967 • 978 citations

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

1977 • 900 citations

Studies on plant amylases

1932 • 727 citations

A new class of angiotensin-converting enzyme inhibitors

1980 • 704 citations

Zur quantitativen Bestimmung der Kollagenase

1963 • 352 citations

A continuous spectrophotometric assay for Clostridium histolyticum collagenase

1981 • 236 citations

Design of potent reversible inhibitors for thermolysin. Peptides containing zinc coordinating ligands and their use in affinity chromatography

1979 • 151 citations

Pseudomonas aeruginosa elastase. Development of a new substrate, inhibitors, and an affinity ligand.

1980 • 141 citations

Inhibition of thermolysin and carboxypeptidase A by phosphoramidates

1979 • 138 citations

Design of potent and specific inhibitors of carboxypeptidases A and B

1979 • 117 citations

Peptide hydroxamic acids as inhibitors of thermolysin

1978 • 116 citations

Clostridium histolyticum collagenase: Its purification and properties

1958 • 100 citations

Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II, bovine chymotrypsin A.alpha., and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates

1984 • 91 citations

Metal-coordinating substrate analogs as inhibitors of metalloenzymes.

1979 • 81 citations

Hydrolysis of synthetic peptides by collagenase

1960 • 65 citations

Fluorescence determination of carboxypeptidase A activity based on electronic energy transfer

1972 • 61 citations

Collagenase enzymes from Clostridium: characterization of individual enzymes

1976 • 54 citations

Quantitativer kolorimetrischer Test auf Kollagenase

1960 • 54 citations

A neutral protease in rheumatoid synovial fluid capable of attacking the telopeptide regions of polymeric collagen fibrils

1975 • 53 citations

Active site directed irreversible inhibition of thermolysin

1978 • 50 citations

18 The Collagenases

1971 • 50 citations

Affinity labeling of bovine carboxypeptidase A γ Leu by N-bromoacetyl-N-methyl-L-phenylalanine. II. Sites of modification

1971 • 49 citations

Use of substrates with fluorescent donor and acceptor chromophores for the kinetic assay of hydrolases

1973 • 47 citations

A reproducible quantitative collagenase radiofibril assay

1972 • 44 citations

Reactivity of bovine blood coagulation factor IXa.beta., factor Xa.beta., and factor XIa toward fluorogenic peptides containing the activation site sequences of bovine factor IX and factor X

1983 • 34 citations

Kinetic Studies on the Action of Collagenase

1965 • 32 citations

[91] Collagenase from Clostridium histolyticum

1962 • 31 citations

A fluorogenic substrate for angiotensin-converting enzyme

1977 • 30 citations

Evidence for a Carboxyl Group at the Active Center of Bovine Carboxypeptidase B

1971 • 27 citations

Specificity of bacterial collagenase: Studies with peptides newly synthesized using the solid-phase method

1972 • 26 citations

Inhibition of the collagenase from Clostridium histolyticum by phosphoric and phosphonic amides

1983 • 25 citations

The geometry of the thioester group and its implications for the chemistry of acyl coenzyme a

1983 • 17 citations

A New Method for the Assay of Tissue Collagenase

1972 • 16 citations

The thiolesterase activity of leucine aminopeptidase

1972 • 10 citations

Evidence for a difference in mechanism between the reactions with carboxypeptidase A of the (−) and (+)-enantiomers of a thiolester substrate

1975 • 8 citations