Regulation of primary response and specific genes in adrenal cells by peptide hormones and growth factors

The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins

1988 • 3,479 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

The Cloning of a Family of Genes That Encode the Melanocortin Receptors

1992 • 1,616 citations

Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor

1991 • 1,247 citations

PRIMARY RESPONSE GENES INDUCED BY GROWTH FACTORS AND TUMOR PROMOTERS

1991 • 1,078 citations

Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor

1991 • 808 citations

Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.

1993 • 767 citations

Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.

1993 • 713 citations

Jun-B differs in its biological properties from, and is a negative regulator of, c-Jun

1989 • 698 citations

Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers

1989 • 676 citations

Parallel Association of Fos and Jun Leucine Zippers Juxtaposes DNA Binding Domains

1989 • 607 citations

jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun

1989 • 488 citations

Regulation of the Synthesis of Steroidogenic Enzymes in Adrenal Cortical Cells by ACTH

1988 • 488 citations

TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a fos binding sequence

1990 • 444 citations

Nuclear Proto-Oncogenes Fos and Jun

1990 • 392 citations

JunB differs from c-Jun in its DNA-binding and dimerization domains, and represses c-Jun by formation of inactive heterodimers.

1993 • 323 citations

ANTISENSE RNA

1991 • 256 citations

67th ANNUAL MEETING OF THE ENDOCRINE SOCIETY

1985 • 233 citations

Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1

1990 • 221 citations

Enhanced jun gene expression is an early genomic response to transforming growth factor beta stimulation.

1989 • 213 citations

Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence.

1986 • 211 citations

ACTH induces up-regulation of ACTH receptor mRNA in mouse and human adrenocortical cell lines

1994 • 170 citations

Regulation of corticotropin receptor number and messenger RNA in cultured human adrenocortical cells by corticotropin and angiotensin II.

1994 • 155 citations

Corticotropin positively regulates its own receptors and cAMP response in cultured bovine adrenal cells.

1989 • 147 citations

Biochemical diversity of cAMP-dependent transcription of steroid hydroxylase genes in the adrenal cortex.

1994 • 135 citations

Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE).

1990 • 134 citations

Characterization of Insulin-Like Growth Factor I and Insulin Receptors on Cultured Bovine Adrenal Fasciculata Cells. Role of these Peptides on Adrenal Cell Function*

1988 • 126 citations

Tissue-Specific, Cyclic Adenosine 3′,5′-Monophosphate-lnduced, and Phorbol Ester-Repressed Transcription from the Human P450c17 Promoter in Mouse Cells

1990 • 122 citations

Processing of Angiotensin II (A-II) and (Sar¹Ala⁸)A-II by Cultured Bovine Adrenocortical Cells*

1986 • 95 citations

Different members of the jun proto-oncogene family exhibit distinct patterns of expression in response to type beta transforming growth factor.

1990 • 91 citations

Negative regulation of gene expression by TGF‐β

1992 • 71 citations

Regulation of angiotensin II receptors and steroidogenic responsiveness in cultured bovine fasciculata and glomerulosa adrenal cells

1988 • 69 citations

Type beta transforming growth factor affects adrenocortical cell-differentiated functions.

1987 • 68 citations

Regulation of type 1 angiotensin II receptor messenger ribonucleic acid expression in human adrenocortical carcinoma H295 cells.

1994 • 64 citations

Transforming Growth Factor β₁is a Negative Regulator of Steroid 17α-Hydroxylase Expression in Bovine Adrenocortical Cells*

1991 • 63 citations

Transforming growth factor β treatment decreases ACTH receptors on ovine adrenocortical cells

1989 • 61 citations

A cAMP-regulatory sequence (CRS1) of CYP17 is a cellular target for the homeodomain protein Pbx1.

1994 • 58 citations

Regulation of c-fos, c-jun and jun-B messenger ribonucleic acids by angiotensin-II and corticotropin in ovine and bovine adrenocortical cells.

1992 • 58 citations

Regulation of bovine adrenal cell corticotropin receptor mRNA levels by corticotropin (ACTH) and angiotensin-II (A-II)

1994 • 56 citations

Effects of transforming growth factor-beta 1 on human adrenocortical fasciculata-reticularis cell differentiated functions.

1994 • 56 citations

Transforming Growth Factor-β Inhibits Steroid 17α-Hydroxylase Cytochrome P-450 Expression in Ovine Adrenocortical Cells*

1990 • 55 citations

Effects of transforming growth factor beta on ovine adrenocortical cells

1988 • 54 citations

Regulation of corticotropin and steroidogenic enzyme mRNAs in human fetal adrenal cells by corticotropin, angiotensin-II and transforming growth factor β1

1994 • 52 citations

Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C.

1992 • 52 citations

Regulation of 3β-Hydroxysteroid Dehydrogenase in Adrenocortical Cells: Effects of Angiotensin-II and Transforming Growth Factor Beta

1991 • 51 citations

Regulation of c-fos, c-jun,jun-B, and c-mycMessenger Ribonucleic Acids by Gonadotropin and Growth Factors in Cultured Pig Leydig Cell^*

1991 • 48 citations

Characterization and regulation of the angiotensin II type‐1 receptor (binding and mRNA) in human adrenal fasciculata‐reticularis cells

1993 • 45 citations

Ovine Fetal Adrenal Synthesis of Cortisol: Regulation by Adrenocorticotropic Angiotensin II and Transforming Growth Factor-β*

1991 • 43 citations

Synergistic effects of corticotropin and insulin-like growth factor I on corticotropin receptors and corticotropin responsiveness in cultured bovine adrenocortical cells

1989 • 43 citations

Transforming Growth Factor ß1: An Autocrine Regulator of Adrenocortical Steroidogenesis

1991 • 40 citations

Prolonged ACTH infusion suppresses aldosterone secretion in spite of high renin activity

1985 • 40 citations

Interaction of Phorbol Ester and Adrenocorticotropin in the Regulation of Steroidogenic P450 Genes in Human Fetal and Adult Adrenal Cell Cultures*

1991 • 38 citations

Regulation of 11β- and 17α-Hydroxylases in Cultured Bovine Adrenocortical Cells: 3′,5′-Cyclic Adenosine Monophosphate, Insulin-Like Growth Factor-I, and Activators of Protein Kinase C*

1990 • 38 citations

Characterization and coupling of angiotensin-II receptor subtypes in cultured bovine adrenal fasciculata cells

1992 • 37 citations

Up regulation of corticotrophin receptors by ACTH1–24 in normal and hypophysectomized rabbits

1980 • 36 citations

Phorbol ester mimics ACTH action in corticoadrenal cells stimulating steroidogenesis, blocking cell cycle, changing cell shape, and inducing c-fos proto-oncogene expression.

1990 • 36 citations

Identification and characterization of angiotensin-II receptor subtypes in cultured bovine and human adrenal fasciculata cells and PC12W cells.

1993 • 35 citations

Adrenocorticotropin Increases Expression of c-fos and β-Actin Genes in the Rat Adrenals*

1990 • 34 citations

Expression of 11 beta-hydroxylase and 21-hydroxylase in long-term cultures of bovine adrenocortical cells requires extracellular matrix factors.

1992 • 34 citations

Regulation of 3β-Hydroxysteroid Dehydrogenase/Δ_5→4- Isomerase Expression by Adrenocorticotropin in Bovine Adrenocortical Cells*

1991 • 31 citations

Transiently Elevated Levels of c-fosand c-mycOncogene Messenger Ribonucleic Acids in Cultured Murine Leydig Tumor Cells after Addition of Human Chorionic Gonadotropin

1989 • 30 citations

Administration of adrenocorticotropic hormone (ACTH) enhances Fos expression in the rat adrenal cortex

1990 • 29 citations

Regulation of type 1 angiotensin II receptor messenger ribonucleic acid expression in human adrenocortical carcinoma H295 cells

1994 • 28 citations

Corticotropin regulation of 3β-hydroxysteroid dehydrogenase/Δ5→4-isomerase in ovine adrenocortical cells: Inhibition by transforming growth factor β

1991 • 27 citations

Insulin-like growth factor-I and insulin increase the stimulatory guanine nucleotide binding protein (Gs) in cultured bovine adrenal cells

1989 • 26 citations

Regulation of c-fos, c-jun and jun-B messenger ribonucleic acids by angiotensin-II and corticotropin in ovine and bovine adrenocortical cells

1992 • 26 citations

Regulation of acth receptor mrna and binding sites by acth and angiotensin II in cultured human and bovine adrenal fasciculata cells.

1995 • 25 citations

Cooperative stimulation of specific gene transcription by epidermal growth factor and transforming growth factor type beta 1.

1990 • 24 citations

A 3',5'-cyclic adenosine monophosphate-dependent pathway is responsible for a rapid increase in c-fos messenger ribonucleic acid by adrenocorticotropin.

1992 • 24 citations

Effects of transforming growth factor-beta 1 on human adrenocortical fasciculata-reticularis cell differentiated functions

1994 • 24 citations

Stimulatory Effect of Insulin and Insulin-Like Growth Factor I on G_iProteins and Angiotensin-II-Induced Phosphoinositide Breakdown in Cultured Bovine Adrenal Cells*

1990 • 24 citations

Induction of c-fos-like protein in the rat adrenal cortex by acute stress —immunocytochemical evidence

1989 • 22 citations

A novel 3',5'-cyclic adenosine monophosphate-responsive sequence in the bovine CYP17 gene is a target of negative regulation by protein kinase C.

1992 • 20 citations

Regulation of Guanine Nucleotide Binding Regulatory Proteins in Cultured Adrenal Cells by Adrenocorticotropin and Angiotensin-II*

1991 • 20 citations

Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C

1992 • 20 citations

Opposite effects of angiotensin-II and corticotropin on bovine adrenocortical cell steroidogenic responsiveness

1991 • 19 citations

Angiotensin‐II‐induced expression of proto‐oncogene (c‐fos, jun‐B and c‐jun) mRNA in bovine adrenocortical fasciculata cells (BAC) is mediated by AT‐1 receptors

1992 • 17 citations

The Response of 21-Hydroxylase Messenger Ribonucleic Acid Levels to Adenosine 3′,5′-Monophosphate and 12-O-Tetradecanoylphorbol-13-Acetate in Bovine Adrenocortical Cells Is Dependent on Culture Conditions*

1991 • 16 citations

Regulation by growth factors of angiotensin II type-1 receptor and the alpha subunit of Gq and G11 in bovine adrenal cells.

1994 • 15 citations

ADRENOCORTICAL RESPONSE UPON REPEATED STIMULATION WITH CORTICOTROPHIN IN PATIENTS LACKING ENDOGENOUS CORTICOTROPHIN SECRETION

1977 • 14 citations

Expression of 11 beta-hydroxylase and 21-hydroxylase in long-term cultures of bovine adrenocortical cells requires extracellular matrix factors

1992 • 13 citations

A 3',5'-cyclic adenosine monophosphate-dependent pathway is responsible for a rapid increase in c-fos messenger ribonucleic acid by adrenocorticotropin

1992 • 12 citations

A novel 3',5'-cyclic adenosine monophosphate-responsive sequence in the bovine CYP17 gene is a target of negative regulation by protein kinase C

1992 • 12 citations

Identification and characterization of angiotensin-II receptor subtypes in cultured bovine and human adrenal fasciculata cells and PC12W cells

1993 • 11 citations

The sequence of the 5'-end of the rat CYP17 gene, the transcription initiation site and a comparison with the homologous genes of other species

1993 • 8 citations

Regulation by growth factors of angiotensin II type-1 receptor and the alpha subunit of Gq and G11 in bovine adrenal cells

1994 • 6 citations

Characterization and regulation of corticotropin and angiotensin-II receptors in human and bovine adrenal cells

1996 • 1 citations