Autoimmune Lymphoproliferative Syndrome with Defective Fas: Genotype Influences Penetrance

Apoptosis by Death Factor

1997 • 5,038 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Textbook of Rheumatology

1985 • 1,671 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand

1994 • 1,549 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

1991 • 1,027 citations

Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism

1995 • 543 citations

FasGene Mutations in the Canale–Smith Syndrome, an Inherited Lymphoproliferative Disorder Associated with Autoimmunity

1996 • 486 citations

Textbook of Rheumatology

1994 • 434 citations

Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing.

1995 • 398 citations

Induction of various autoantibodies by mutant gene lpr in several strains of mice.

1984 • 390 citations

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

1996 • 379 citations

Clinical, Immunologic, and Genetic Features of an Autoimmune Lymphoproliferative Syndrome Associated With Abnormal Lymphocyte Apoptosis

1997 • 374 citations

Human gene mutation

1993 • 316 citations

A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.

1992 • 310 citations

Mutation of the signal peptide-encoding region of the preproparathyroid hormone gene in familial isolated hypoparathyroidism.

1990 • 293 citations

Mutations in the Fas Antigen in Patients With Multiple Myeloma

1997 • 228 citations

Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.

1986 • 224 citations

A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha

1994 • 220 citations

Dideoxy fingerprinting (ddF): A rapid and efficient screen for the presence of mutations

1992 • 212 citations

An N-terminal domain shared by Fas/Apo-1 (CD95) soluble variants prevents cell death in vitro.

1996 • 199 citations

Mutations in the Fas Antigen in Patients With Multiple Myeloma

1997 • 183 citations

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: a molecular and immunological analysis.

1997 • 177 citations

Missense Mutations in the Fas Gene Resulting in Autoimmune Lymphoproliferative Syndrome: A Molecular and Immunological Analysis

1997 • 168 citations

Structure of the human APO‐1 gene

1994 • 165 citations

Mutation Analysis of IL2RG in Human X-Linked Severe Combined Immunodeficiency

1997 • 156 citations

A promoter polymorphism of tumor necrosis factor α associated with systemic lupus erythematosus in African‐Americans

1997 • 141 citations

Characterization of human Fas gene. Exon/intron organization and promoter region.

1995 • 130 citations

Increased Frequency of the Uncommon Allele of a Tumour Necrosis Factor Alpha Gene Polymorphism in Rheumatoid Arthritis and Systemic Lupus Erythematosus

1994 • 122 citations

CD95 (APO-1/Fas) Mutations in Childhood T-Lineage Acute Lymphoblastic Leukemia

1998 • 121 citations

The clinical spectrum in a large kindred with autoimmune lymphoproliferative syndrome caused by a Fas mutation that impairs lymphocyte apoptosis

1998 • 112 citations

Possible involvement of inefficient cleavage of preprovasopressin by signal peptidase as a cause for familial central diabetes insipidus.

1993 • 105 citations

Tumor necrosis factor alpha (TNF-?) gene polymorphism in alopecia areata

1995 • 102 citations

Novel Fas (CD95/APO-1) mutations in infants with a lymphoproliferative disorder.

1998 • 99 citations

Functional analysis of T cell subsets from mice bearing the lpr gene.

1985 • 87 citations

Assignment of the human fas antigen gene (FAS) to 10q24.1

1992 • 86 citations

Differential expression of human Fas mRNA species upon peripheral blood mononuclear cell activation

1995 • 82 citations

Clinical features of SLE

1989 • 76 citations

Review:Death Domain Receptors and Their Role in Cell Demise

1998 • 62 citations

Fas/Apo1 mutations and autoimmune lymphoproliferative syndrome in a patient with type 2 autoimmune hepatitis

1997 • 62 citations

Detection of polymorphisms within the FAS cDNA gene sequence by GC-clamp denaturing gradient gel eletrophoresis

1994 • 48 citations

Autoimmunity in Mice Bearing lpr^cs: A Novel Mutant Gene

1994 • 41 citations

Factor XSanto Domingo. Evidence that the severe clinical phenotype arises from a mutation blocking secretion.

1991 • 36 citations

Polymorphism of the Tumor Necrosis Factor Genes in Patients with Dermatitis herpetiformis

1994 • 22 citations

Distinctive Expression of Iprcg in the Heterozygous State on Different Genetic Backgrounds

1993 • 16 citations

HLA Class II Associations in African-American Female Patients with Graves' Disease

1996 • 15 citations