Requirements for the solubilization of immune aggregates by complement: assembly of a factor B-dependent C3-convertase on the immune complexes.

THE PREPARATION OF 131I-LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC RADIOACTIVITY

1963 • 10,322 citations

A Method of Trace Iodination of Proteins for Immunologic Studies

1966 • 2,148 citations

Complement

1975 • 594 citations

Third component of human complement: purification from plasma and physicochemical characterization

1976 • 523 citations

Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase.

1975 • 474 citations

ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUM

1969 • 430 citations

A new complement function: solubilization of antigen-antibody aggregates.

1975 • 303 citations

FORMATION AND FUNCTIONAL SIGNIFICANCE OF A MOLECULAR COMPLEX DERIVED FROM THE SECOND AND THE FOURTH COMPONENT OF HUMAN COMPLEMENT

1967 • 244 citations

Studies on the mechanism of solubilization of immune precipitates by serum.

1976 • 162 citations

Properties of highly purified human properdin.

1968 • 158 citations

C'1 ESTERASE EFFECT ON ACTIVITY AND PHYSICOCHEMICAL PROPERTIES OF THE FOURTH COMPONENT OF COMPLEMENT

1965 • 131 citations

THE ROLE OF PROPERDIN IN THE ALTERNATE PATHWAY OF COMPLEMENT ACTIVATION

1974 • 118 citations

Properdin- and nephritic factor-dependent C3 convertases: requirement of native C3 for enzyme formation and the function of bound C3b as properdin receptor.

1975 • 115 citations

REACTION MECHANISM OF THE ALTERNATIVE PATHWAY OF COMPLEMENT FIXATION

1973 • 110 citations

A molecular concept of the properdin pathway.

1976 • 98 citations

Properdin: initiation of alternative complement pathway.

1975 • 84 citations

The reaction of zymosan with the properdin system in normal and C4-deficienct guinea pig serum. Demonstration of C3- and C5-cleaving multi-unit enzymes, both containing factor B, and acceleration of their formation by the classical complement pathway.

1973 • 62 citations

Mechanism of Solubilization of Immune Aggregates by Complement. Implications for Immunopathology

1976 • 59 citations

Studies on the sub-unit structure of human properdin

1974 • 53 citations

Reversible adsorption of C′2 by EAC′4: Role of Mg2+, enumeration of competent SAC′4, two-step nature of C′2a fixation and estimation of its efficiency

1966 • 47 citations

The Reaction of Zymosan with the Properdin System: Isolation of Purified Factor D from Guinea Pig Serum and Study of Its Reaction Characteristics

1974 • 42 citations

Multiple sedimenting species of properdin in human serum and interaction of purified properdin with the third component of complement.

1976 • 40 citations

Solid phase radioimmunoassay of properdin

1973 • 30 citations

Antibody-Complement Complexes

1965 • 29 citations

Loss of Precipitating Activity of Antibody without Destruction of Binding Sites

1958 • 28 citations