Natural killing and antibody-dependent cytotoxicity by lymphocyte subpopulations in young and aging humans

„Natural”︁ killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype

1975 • 1,743 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity

1975 • 1,308 citations

Natural Cell-Mediated Immunity

1978 • 1,063 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells

1975 • 844 citations

Natural Cytotoxic Reactivity of Human Lymphocytes Against a Myeloid Cell Line: Characterization of Effector Cells

1977 • 493 citations

AGEING, IMMUNE RESPONSE, AND MORTALITY

1974 • 480 citations

Frequency of Pathological Proteins (M‐components) in 6,995 Sera from an Adult Population

1966 • 444 citations

Reactivity of lymphocytes from normal persons on cultured tumor cells.

1973 • 383 citations

Developmental immunobiology

1978 • 378 citations

Impaired Lymphocyte Function in Aged Humans

1974 • 350 citations

Lymphocyte Phytohemagglutinin Responsiveness, Immunoglobulins and Autoantibodies in Aging Humans

1973 • 286 citations

Natural Killer Cells in the Mouse: An Alternative Immune Surveillance Mechanism?

1978 • 205 citations

Mitogenic Effect of Phytohaemagglutinin at Different Ages

1967 • 204 citations

Cytotoxic lymphocytes from normal donors. A functional marker of human non-T lymphocytes.

1975 • 193 citations

Destruction of Human Lymphoid Tissue-Culture Cell Lines by Human Peripheral Lymphocytes in 51Cr-Release Cellular Cytotoxicity Assays2

1974 • 183 citations

Subpopulations of human T lymphocytes

1977 • 178 citations

Killer cells: a functional comparison between natural, immune T-cell and antibody-dependent in vitro systems.

1976 • 174 citations

Suppressor Lymphocytes in Young and Aged Humans

1977 • 169 citations

Activation of Human Natural Killer Cells Cytotoxic for Human Leukemia Cells by Purified Interferon

1979 • 168 citations

ENZYMATIC OR PHARMACOLOGICAL FIBRINOLYSIS?

1964 • 154 citations

RECIPROCAL CHANGE WITH AGE IN ANTIBODY TO EXTRINSIC AND INTRINSIC ANTIGENS

1968 • 151 citations

Loss of Fc receptors for IgG from human T lymphocytes exposed to IgG immune complexes

1978 • 146 citations

Lymphocyte cytotoxicity reactions to leukemia‐associated antigens in identical twins

1972 • 143 citations

Genetically determined immune deficiency as the predisposing cause of “autoimmunity” and lymphoid neoplasia

1971 • 138 citations

Direct evidence that natural killer cells in nonimmune spleen cell populations prevent tumor growth in vivo

1979 • 136 citations

Antibody-Dependent Cytotoxicity Mediated by Human Fc-Receptor-Bearing Cells Lacking Markers for B- and T-Lymphocytes

1974 • 131 citations

Defective spontaneous and antibody-dependent cytotoxicity mediated by E-rosette-positive and E-rosette-negative cells in untreated patients with chronic lymphocytic leukemia: augmentation by in vitro treatment with interferon.

1980 • 130 citations

Humoral immunity in aged mice. II. Increased suppressor T cell activity in immunologically deficient old mice.

1976 • 124 citations

Depression of cell-mediated immunity in old age and the immunopathic diseases, lupus erythematosus, chronic hepatitis and rheumatoid arthritis.

1973 • 124 citations

Immunologic studies of aging. V. Impaired proliferation of PHA responsive human lymphocytes in culture.

1980 • 116 citations

Immunobiology of aging: Evaluation of current status

1976 • 115 citations

Effect of age on cell-mediated immunity in long-lived mice.

1975 • 93 citations

Age-Related Decline in Response to Phytohemagglutinin and Pokeweed Mitogen by Spleen Cells from Hamsters and a Long-Lived Mouse Strain

1973 • 87 citations

Spontaneous and antibody-dependent cell-mediated cytotoxicity by human T cell subpopulations.

1978 • 85 citations

Evidence that Natural Cytotoxicity and Antibody-Dependent Cellular Cytotoxicity Are Mediated in Humans by the Same Effector Cell Populations

1979 • 82 citations

ASSOCIATION BETWEEN PRE-TRANSPLANT NATURAL KILL AND GRAFT-VERSUS-HOST DISEASE AFTER STEM-CELL TRANSPLANTATION

1979 • 74 citations

Cellular Microcytotoxicity in Human Tumor Systems: Analysis of Results2

1975 • 73 citations

Subpopulations of human T lymphocytes. X. Alterations in T, B, third population cells, and T cells with receptors for immunoglobulin M (Tmu) or G (Tgamma) in aging humans.

1979 • 72 citations

Heterogeneity of human natural killer cell populations

1978 • 71 citations

Humoral Immunity in Aged Mice

1976 • 69 citations

Effects of metabolic inhibitors on spontaneous and interferon-boosted human natural killer cell activity.

1980 • 64 citations

Progressive loss in vitro of cellular immunity with ageing in strains of mice susceptible to autoimmune disease.

1971 • 60 citations

Fc receptors on human T lymphocytes

1979 • 52 citations

Natural Killing of Measles-Infected Cells by Human Lymphocytes

1979 • 50 citations

Circulating suppressor cells in man as a function of age

1978 • 50 citations

The Requirement for Macrophages in the Augmentation of Natural Killer Cell Activity by BCG

1979 • 47 citations

Age and genetic influence on immunity in NZB and autoimmune—Resistant mice

1976 • 42 citations

Depletion of NK by Cellular Immunoadsorption

1979 • 39 citations

Quantitative comparison of K cell potential in human T and null cells

1978 • 37 citations

Immunoglobulin-Independent Natural Cytotoxicity of Fc Receptor-Bearing Human Blood Lymphocytes to Mumps Virus-Infected Target Cells

1978 • 34 citations

Subpopulations of Human T Lymphocytes

1979 • 33 citations

Natural cell‐mediated cytotoxicity in hamsters

1979 • 31 citations

ANTIBODY-DEPENDENT LYMPHOCYTE KILLER FUNCTION AND AGE

1973 • 29 citations

Immunoregulation in aged humans

1980 • 29 citations

Antibody-dependent lymphocyte killer function and age.

1973 • 28 citations

Immunologicc activity of the aged.

1971 • 27 citations

Evidence for antibody-dependent cell-mediated cytotoxicity by T cells bearing receptors for IgG.

1979 • 23 citations

Human Lymphocyte Sub-Populations and K Cells

1976 • 21 citations

INHIBITION AS WELL AS AUGMENTATION OF MOUSE NK ACTIVITY BY PYRAN COPOLYMER AND ADRIAMYCIN

1980 • 20 citations

Concanavalin A-induced suppressor cell activity for T-cell proliferative responses: Autologous and allogeneic suppression in aging humans

1980 • 19 citations

Restriction of immunoglobulin heterogeneity, autoimmunity and serum protein levels in aged people.

1976 • 18 citations

Autoimmunity, immunoglobulins and T lymphocyte population in old age.

1973 • 11 citations

Natural killer cells—Immunologist's fancy?

1980 • 9 citations