Regulation of Cell-Mediated Immunity in Leishmaniasis

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

Two types of mouse helper T-cell clone

1987 • 813 citations

Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens.

1988 • 713 citations

Progress in immunology

1968 • 577 citations

A functional dichotomy in CD4+ T lymphocytes

1988 • 369 citations

Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes.

1988 • 236 citations

Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice.

1985 • 225 citations

Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection.

1977 • 225 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Cell-mediated immunity in American visceral leishmaniasis: reversible immunosuppression during acute infection

1981 • 215 citations

Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes.

1987 • 212 citations

Immunological regulation of experimental cutaneous leishmaniasis. IV. Prophylactic effect of sublethal irradiation as a result of abrogation of suppressor T cell generation in mice genetically susceptible to leishmania tropica

1981 • 199 citations

IMMUNE RESPONSE TO CHEMICALLY MODIFIED FLAGELLIN

1972 • 196 citations

Functional heterogeneity of CD4+ T cells in leishmaniasis

1989 • 171 citations

Murine cutaneous leishmaniasis: resistance correlates with the capacity to generate interferon-gamma in response to Leishmania antigens in vitro.

1986 • 169 citations

Molecular cloning of the major surface antigen of leishmania.

1988 • 169 citations

Cell-mediated immune response in Indian kala-azar and post-kala-azar dermal leishmaniasis

1983 • 167 citations

Immunologic regulation of experimental cutaneous leishmaniasis. V. Characterization of effector and specific suppressor T cells.

1982 • 163 citations

Role of L3T4+ and LyT-2+ cells in experimental visceral leishmaniasis.

1988 • 162 citations

Cutaneous leishmaniasis in anti-IgM-treated mice: enhanced resistance due to functional depletion of a B cell-dependent T cell involved in the suppressor pathway.

1984 • 153 citations

Phenotypic and functional heterogeneity of CD4+ T cells

1988 • 142 citations

Mechanism of lethal effect of human serum upon Leishmania donovani.

1980 • 142 citations

Exacerbation of murine cutaneous leishmaniasis by adoptive transfer of parasite-specific helper T cell populations capable of mediating Leishmania major-specific delayed-type hypersensitivity.

1984 • 140 citations

Suppressive effect of cyclosporin A on the development of Leishmania tropica-induced lesions in genetically susceptible BALB/c mice.

1986 • 138 citations

Immunosuppression in Kenyan visceral leishmaniasis.

1983 • 133 citations

Macrophage activation by interferon‐γ from host‐protective T cells is inhibited by interleukin (IL) 3 and IL 4 produced by disease‐promoting T cells in leishmaniasis

1989 • 130 citations

Prophylactic immunization against experimental leishmaniasis: I. Protection induced in mice genetically vulnerable to fatal Leishmania tropica infection.

1982 • 118 citations

Involvement of specific Lyt‐2⁺ T cells in the immunological control of experimentally induced murine cutaneous leishmaniasis

1987 • 108 citations

Experimental cutaneous leishmaniasis. V. Protective immunity in subclinical and self-healing infection in the mouse.

1976 • 101 citations

The present and future of vaccination for cutaneous leishmaniasis.

1980 • 101 citations

Experimental cutaneous leishmaniasis. 3. Effects of thymectomy on the course of infection of CBA mice with Leishmania tropica.

1972 • 97 citations

Antigen-specific and nonspecific mediators of T cell/B cell cooperation. I. Evidence for their production by different T cells.

1975 • 94 citations

RESISTANCE AND ABROGATION OF RESISTANCE TO CUTANEOUS LEISHMANIASIS IN RECONSTITUTED BALB/c NUDE MICE

1981 • 83 citations

Prophylactic immunization against experimental leishmaniasis. III. Protection against fatal Leishmania tropica infection induced by irradiated promastigotes involves Lyt-1+2- T cells that do not mediate cutaneous DTH.

1984 • 79 citations

Cellular cooperation during in vivo anti-hapten antibody responses. I. The effect of cell number on the response.

1975 • 77 citations

Interleukin 2 deficiency in murine Leishmaniasis donovani and its relationship to depressed spleen cell responses to phytohemagglutinin.

1983 • 73 citations

Experimental cutaneous leishmaniasis. I. Nonspecific immunodepression in BALB/c mice infected with Leishmania tropica.

1981 • 71 citations

Genetically determined susceptibility to Leishmania tropica infection is expressed by haematopoietic donor cells in mouse radiation chimaeras

1980 • 68 citations

B lymphocytes are required for the generation of T cells that mediate healing of cutaneous leishmaniasis.

1986 • 68 citations

Immunological Features of Kala-Azar

1978 • 66 citations

Leishmania donovani infection in heterozygous and recombinant H-2 haplotype mice

1983 • 62 citations

Antigen-Specific and Nonspecific Mediators of T Cell/B Cell Cooperation

1975 • 55 citations

Prophylactic treatment of BALB/c mice with cyclosporine A and its analog B-5-49 enhances resistance to Leishmania major.

1986 • 53 citations

Cellular Cooperation During in Vivo Anti-Hapten Antibody Responses

1975 • 51 citations

Prophylactic immunization against experimental leishmaniasis. V. Mechanism of the anti-protective blocking effect induced by subcutaneous immunization against Leishmania major infection.

1985 • 51 citations

Suppression of interleukin-2 production by macrophages in genetically susceptible mice infected with Leishmania major

1986 • 49 citations

Monocyte suppression of antigen-specific lymphocyte responses in diffuse cutaneous leishmaniasis patients from the Dominican Republic.

1984 • 48 citations

Identification of Leishmania genes encoding proteins containing tandemly repeating peptides.

1987 • 48 citations

Distinctive cellular immunity in genetically susceptible BALB/c mice recovered from Leishmania major infection or after subcutaneous immunization with killed parasites.

1987 • 45 citations

LACK OF A CORRELATION BETWEEN CELL-MEDIATED IMMUNITY TO THE CARRIER AND THE CARRIER-HAPTEN HELPER EFFECT

1974 • 44 citations

Immunization of susceptible BALB/c mice against Leishmania braziliensis,

1985 • 43 citations

Cell-mediated immunity in experimental cutaneous leishmaniasis

1986 • 43 citations

Specific suppression of responses to Leishmania tropica by a cloned T-cell line

1983 • 43 citations

Suppression of IL-2 production by cryopreserved peripheral blood mononuclear cells from patients with active visceral leishmaniasis in Sicily.

1988 • 43 citations

Variable expression of the murine natural resistance gene Lsh in different macrophage populations infected in vitro with Leishmania donovani

1987 • 41 citations

Susceptibility to murine cutaneous leishmaniasis correlates with the capacity to generate interleukin 3 in response to leishmania antigen in vitro

1988 • 41 citations

Immunological responses of L. donovani infection in mice and significance of T cell in resistance to experimental leishmaniasis.

1980 • 40 citations

New Developments with Human and Veterinary Vaccines

1981 • 40 citations

Dissociation of T Cell Helper Function and Delayed Hypersensitivity

1974 • 33 citations

New developments with human and veterinary vaccines

1981 • 33 citations

T-lymphocytes recognise Leishmania glycoconjugates

1985 • 33 citations

An H-11-linked gene has a parallel effect on Leishmania major and L. donovani infections in mice

1985 • 29 citations

Response of BALB/c Mice to Leishmanial Infection

1985 • 29 citations

Cytophilic and Opsonic Antibodies in Visceral Leishmaniasis in Mice

1980 • 28 citations

Cercariometry and the epidemiology of schistosomiasis

1986 • 26 citations

Immunization of susceptible BALB/c mice against Leishmania braziliensis,

1985 • 25 citations

Reversibility of acute alcohol cardiac depression: ³¹ P NMR in hamsters

1988 • 18 citations

Prophylactic immunization against experimental leishmaniasis. VI. Comparison of protective and disease-promoting T cells.

1987 • 16 citations

Do sugar residues contribute to the antigenic determinants responsible for protection and/or abolition of protection in Leishmania-infected BALB/c mice?

1986 • 13 citations

The Role of Specific T Cell Subpopulations in Murine Cutaneous Leishmaniasis

1986 • 11 citations

Distinct IL-3 activation profile induced by intravenous versus subcutaneous routes of immunization

1989 • 10 citations