Costimulatory molecule OX40L is critical for both Th1 and Th2 responses in allergic inflammation

Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.

1996 • 1,382 citations

Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysmography

1997 • 1,294 citations

OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

2001 • 638 citations

Ox-40 Ligand: A Potent Costimulatory Molecule for Sustaining Primary CD4 T Cell Responses

1998 • 515 citations

Antigens of activated rat T lymphocytes including a molecule of 50,000 Mr detected only on CD4 positive T blasts

1987 • 453 citations

Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells

1995 • 398 citations

The OX40 Costimulatory Receptor Determines the Development of CD4 Memory by Regulating Primary Clonal Expansion

2000 • 395 citations

CD4 T Cell Cytokine Differentiation: The B Cell Activation Molecule, OX40 Ligand, Instructs CD4 T Cells to Express Interleukin 4 and Upregulates Expression of the Chemokine Receptor, Blr-1

1998 • 358 citations

T cell co-stimulatory molecules other than CD28

1999 • 349 citations

Ox40-Ligand Has a Critical Costimulatory Role in Dendritic Cell:T Cell Interactions

1999 • 320 citations

Blocking OX-40/OX-40 Ligand Interaction In Vitro and In Vivo Leads to Decreased T Cell Function and Amelioration of Experimental Allergic Encephalomyelitis

1999 • 250 citations

OX40 Costimulation Enhances Interleukin-4 (IL-4) Expression at Priming and Promotes the Differentiation of Naive Human CD4+ T Cells Into High IL-4–Producing Effectors

1998 • 247 citations

Critical Contribution of Ox40 Ligand to T Helper Cell Type 2 Differentiation in Experimental Leishmaniasis

2000 • 235 citations

Accessory Molecule and Costimulation Requirements for CD4 T Cell Response

1997 • 231 citations

CD134L Expression on Dendritic Cells in the Mesenteric Lymph Nodes Drives Colitis in T Cell-Restored SCID Mice

2001 • 207 citations

Development of Allergic Inflammation in a Murine Model of Asthma Is Dependent on the Costimulatory Receptor Ox40

2001 • 204 citations

Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness – a murine model

1999 • 202 citations

Therapeutic efficacy of OX-40 receptor antibody depends on tumor immunogenicity and anatomic site of tumor growth.

2000 • 196 citations

IL-13 and IFN-γ: Interactions in Lung Inflammation

2001 • 182 citations

CD28-Independent Costimulation of T Cells by OX40 Ligand and CD70 on Activated B Cells

1999 • 180 citations

B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens.

1997 • 172 citations

Eotaxin

1999 • 168 citations

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model.

1996 • 139 citations

4-1BBL Cooperates with B7-1 and B7-2 in Converting a B Cell Lymphoma Cell Line into a Long-Lasting Antitumor Vaccine

1999 • 130 citations

NF-kappa B/Rel transcription factors: c-Rel promotes airway hyperresponsiveness and allergic pulmonary inflammation.

1999 • 127 citations

OX40: targeted immunotherapy - implications for tempering autoimmunity and enhancing vaccines

2002 • 112 citations

Amelioration of Experimental Autoimmune Encephalomyelitis with Anti-OX40 Ligand Monoclonal Antibody: A Critical Role for OX40 Ligand in Migration, But Not Development, of Pathogenic T Cells

2001 • 110 citations

Critical Involvement of OX40 Ligand Signals in the T Cell Priming Events During Experimental Autoimmune Encephalomyelitis

2001 • 108 citations

Interleukin‐5 and eosinophils induce airway damage and bronchial hyperreactivity during allergic airway inflammation in BALB/c mice

1997 • 107 citations

B7 Costimulation Is Required for IL-5 and IL-13 Secretion by Bronchial Biopsy Tissue of Atopic Asthmatic Subjects in Response to Allergen Stimulation

1999 • 91 citations

Chemokines and chemokine receptors: their role in allergic airway disease.

1999 • 86 citations

CD28 Interactions with Either CD80 or CD86 Are Sufficient to Induce Allergic Airway Inflammation in Mice

1999 • 85 citations

The OX-40 receptor provides a potent co-stimulatory signal capable of inducing encephalitogenicity in myelin-specific CD4+ T cells

1998 • 67 citations

T cell activation in a murine model of asthma

1996 • 57 citations

Expression of eotaxin, an eosinophil-selective chemokine, parallels eosinophil accumulation in the vesiculobullous stage of incontinentia pigmenti

2002 • 56 citations

B7-1 (CD80) and B7-2 (CD86) Have Complementary Roles in Mediating Allergic Pulmonary Inflammation and Airway Hyperresponsiveness

2000 • 54 citations

Role of the Th2 Cytokines in the Development of Allergen–Induced Airway Inflammation and Hyperresponsiveness

1999 • 52 citations

Both CD80 and CD86 co-stimulatory molecules regulate allergic pulmonary inflammation

1998 • 50 citations

Alterations in lung collectins in an adaptive allergic immune response

2002 • 36 citations

Administration of Pentoxifylline During Allergen Sensitization Dissociates Pulmonary Allergic Inflammation from Airway Hyperresponsiveness

2001 • 32 citations