A Chinese hamster ovary cell mutant with a heat-sensitive, conditional-lethal defect in vacuolar function.

Endocytosis and the recycling of plasma membrane.

1983 • 1,447 citations

Intracellular site of asialoglycoprotein receptor-ligand uncoupling: Double-label immunoelectron microscopy during receptor-mediated endocytosis

1983 • 816 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

NAD-dependent inhibition of protein synthesis by Pseudomonas aeruginosa toxin,.

1975 • 619 citations

Receptor-mediated endocytosis of transferrin in K562 cells.

1983 • 576 citations

Kinetics of internalization and recycling of transferrin and the transferrin receptor in a human hepatoma cell line. Effect of lysosomotropic agents.

1983 • 558 citations

Diphtheria toxin: mode of action and structure

1975 • 552 citations

Receptor-mediated endocytosis of transferrin in developmentally totipotent mouse teratocarcinoma stem cells.

1981 • 497 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

The receptosome: An intermediate organelle of receptor-mediated endocytosis in cultured fibroblasts

1980 • 398 citations

Identification and characterization of a proton pump on lysosomes by fluorescein-isothiocyanate-dextran fluorescence.

1982 • 379 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.

1981 • 341 citations

Acidification of macrophage and fibroblast endocytic vesicles in vitro.

1983 • 331 citations

Golgi membranes contain an electrogenic H+ pump in parallel to a chloride conductance.

1983 • 310 citations

Toxic lectins and related proteins

1982 • 305 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

1981 • 281 citations

An ATP-driven proton pump in clathrin-coated vesicles.

1983 • 253 citations

Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles.

1982 • 234 citations

Receptor-mediated internalization of pseudomonas toxin by mouse fibroblasts

1980 • 176 citations

The proton translocating ATPase responsible for urinary acidification.

1982 • 164 citations

Defective acidification of endosomes in Chinese hamster ovary cell mutants "cross-resistant" to toxins and viruses.

1983 • 153 citations

Mutant Chinese hamster ovary cells pleiotropically defective in receptor-mediated endocytosis.

1983 • 116 citations

The entry of viruses into animal cells

1980 • 96 citations

Receptor-mediated internalization and degradation of diphtheria toxin by monkey kidney cells.

1979 • 90 citations

Monensin blocks the transport of diphtheria toxin to the cell cytoplasm.

1982 • 86 citations

Strains of CHO-K1 cells resistant to Pseudomonas exotoxin A and cross-resistant to diphtheria toxin and viruses

1983 • 84 citations

Failure to release iron from transferrin in a Chinese hamster ovary cell mutant pleiotropically defective in endocytosis.

1984 • 80 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells

1979 • 75 citations

Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments.

1984 • 71 citations

Insertion of diphtheria toxin into and across membranes: role of phosphoinositide asymmetry

1982 • 65 citations

Binding and uptake of diphtheria toxin by toxin-resistant Chinese hamster ovary and mouse cells.

1983 • 51 citations

Immunoprecipitation and partial characterization of diphtheria toxin-binding glycoproteins from surface of guinea pig cells.

1979 • 50 citations

Comparative Toxicities of Diphtherial Toxin and Pseudomonas aeruginosa Exotoxin A: Evidence for Different Cell Receptors

1978 • 39 citations

Chinese hamster ovary cell mutants defective in the internalization of ricin.

1982 • 28 citations

Identification of a cold-sensitive step in the mechanism of modeccin action.

1984 • 24 citations

Binding and Uptake of Diphtheria Toxin by Toxin-Resistant Chinese Hamster Ovary and Mouse Cells

1983 • 11 citations

Chinese Hamster Ovary Cell Mutants Defective in the Internalization of Ricin

1982 • 7 citations