Radiation-induced apoptosis in human ovarian carcinoma cells growing as a monolayer and as multicell spheroids

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Disruption of epithelial cell-matrix interactions induces apoptosis

1994 • 3,167 citations

Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis

1984 • 1,586 citations

p53 Status and the Efficacy of Cancer Therapy in Vivo

1994 • 1,483 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.

1993 • 403 citations

Induction of DNA strand breaks associated with apoptosis during treatment of leukemias.

1993 • 292 citations

Acquired multicellular-mediated resistance to alkylating agents in cancer.

1993 • 280 citations

Radiation-Induced Apoptosis Measured in TK6 Human B Lymphoblast Cells Using the Comet Assay

1993 • 265 citations

Apoptosis induced by inhibition of intercellular contact.

1994 • 256 citations

Heterogeneity in the Development of Apoptosis in Irradiated Murine Tumours of Different Histologies

1993 • 203 citations

Apoptosis in irradiated murine tumors.

1991 • 199 citations

The S-phase cytotoxicity of camptothecin

1991 • 190 citations

To pop or not to pop: p53 as a critical modulator of tumour responsiveness to therapy in vivo?

1995 • 168 citations

Apoptosis in Irradiated Murine Tumors

1991 • 150 citations

Development of apoptosis in irradiated murine tumors as a function of time and dose.

1993 • 117 citations

Development of Apoptosis in Irradiated Murine Tumors as a Function of Time and Dose

1993 • 80 citations

Correlation of Tumor Sensitivity to Low-Dose-Rate Irradiation with G 2 /M-Phase Block and Other Radiobiological Parameters

1993 • 74 citations

Radiation-induced apoptosis: effects of cell age and dose fractionation.

1995 • 47 citations

Reemergence of apoptotic cells between fractionated doses in irradiated murine tumors

1994 • 39 citations

Radiation‐induced apoptosis in human sarcoma and glioma cell lines

1995 • 36 citations

Differential effects of dose rate and superfractionation on survival and cell cycle of V79 cells from spheroid and monolayer culture

1996 • 33 citations

Use of multi‐cell spheroids of ovarian carcinoma as an intraperitoneal radio‐immunotherapy model: Uptake, retention kinetics and dosimetric evaluation

1992 • 31 citations

Tumour cell kinetics and heterogeneity: insights from multicell spheroids.

1992 • 17 citations

Induction of apoptotic or lytic death in an ovarian adenocarcinoma cell line by antibodies generated against a synthetic N-terminal extracellular domain gonadotropin-releasing hormone receptor peptide

1994 • 13 citations

Relationship between cell kinetics and radiation-induced arrest of proliferating cells in G2: relevance to efficacy of radiotherapy.

1989 • 7 citations